فهرست مطالب

Journal of Applied Organometallic Chemistry
Volume:2 Issue: 1, Jan 2022

  • تاریخ انتشار: 1400/10/11
  • تعداد عناوین: 6
|
  • Sadashiv Nagre, Namdeo Dhokale, Navnath Dalvi, Satish Kale, Shankaraiah Konda * Pages 1-6

    In this present investigation, an efficient protocol for the synthesis of bundle of novel substituted benzo[h]quinazoline-2(3H)-thione derivatives was reported. The acetic acid catalyzed benzo[h]quinazoline-2(3H)-thione derivatives were prepared from 2-(substituted arylidene)-1-tetralones, thiourea and green solvent polyethylene glycol-400 with efficient and milder reaction condition. All the novel scaffolds were confirmed by the spectroscopic methods (IR, 1H NMR, Mass and Elemental analysis). The superiority of present method was operational simplicity, easy purification; high yields, easy available catalyst, environmental friendly solvent.

    Keywords: acetic acid, PEG-400, Arylidene-1-tetralones, Thiourea, Benzo[h]quinazoline- 2(3H)-thiones, Green reaction solvent
  • Milind Gaikwad *, Ravina Jadhav, Monika Dalvi, Anil Nagane Pages 7-14
    We have demonstrated novel and eco-friendly acceptable green methods for the synthesis of numerous 1-H-indazole by grinding protocol using NH4Cl  milder acids in an EtOH solvent.  The substituted 1-H-indazole synthesized from the grinding of ortho-hydroxybenzaldehyde with hydrazine hydrate in an Ethanol solvent and NH4Cl  milder acids.  The methods give good yield within less time. The protocol is practically green, milder, higher yield, with short reaction times.
    Keywords: 1-H-indazole EtOH, Hydrazine hydrate, NH4Cl, Grinding
  • Ganesh Pund, Sambhaji Dhumal, Madhav Hebade, Mazahar Farooqui, Bhagwansing Dobhal * Pages 15-23
    An efficient and simple one-pot synthetic protocol has been developed for the first time to synthesize the series of Ethyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylates. This was achieved by the cyclocondensation of aromatic aldehydes, malononitrile, and ethylacetoacetate in the presence of the catalytic amount of Maglumine as a readily available, reusable, and biodegradable catalyst. This technique is very promising asit provides mild reaction conditions, an environmentally benign greener approach, easy workup process, high yield, less reaction time, low cost, and recycled up to five catalytic cycles without substantial loss of catalytic activity or product yield.
    Keywords: Meglumine, Recyclable, Ethyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylates, Reusable, Cyclocondensation
  • Sunil Gaikwad *, Murali Venkata Basavanag Unnamatla Pages 24-30
    The one-pot multicomponent efficient and easily operational protocol has been developed for the synthesis of tetrahydropyrano[2,3-c]pyrazole-5-carbonitrile derivatives. The methods work via the multicomponent reaction between 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one , aldehyde and malononitrile  catalyzed by the silica-supported dodeca tungstophosphoric acid (DTP/SiO2) catalyst. The protocol is practically green, milder reaction condition, higher yield, with short reaction times and recyclability of the catalyst.
    Keywords: DTP, SiO2, Greener solvent, one-pot multicomponant, carbazole-3-carbonitrile
  • Somnath Udgire, Milind Gaikwad, Prakash Patil * Pages 31-38
    A simple, eco-friendly friendly and efficient procedure for the synthesis of Mannich Baseshas been developed via multi-component and one-pot reactions of various aldehydes with aniline, and acetophenone and catalytic amount of Bi(OTf)3 reagent in a DCM solvent.The Bi(OTf)3 acts as a highly potent catalyst ( 0.5 to 1 mol%) for a for the synthesis of Mannich base (1,3-diphenyl-3-(phenylamino)propan-1-one). This protocol is also compatible with a variety of hetero aldehyde carbonyl compounds in excellent yields. Thus, this practical method is developed as a notable medium for these derivatives via a multicomponent reaction.
    Keywords: Bi(OTf)3, one-pot three-component, greener, Mannich reaction
  • Ali Allahresani *, Fatemeh Ghorbanian, MohammadAli Nasseri, Milad Kazemnejadi Pages 39-53

    Bis(2-ethylheptyl) phthalate is an anti-oxidant and anticancer compound that was extracted from the Cynodon dactylon plant stem extract and fully identified and characterized by FTIR, CHN, 1HNMR, 13CNMR, along with various 2D NMR techniques. The phthalate compound was modified and functionalized by polyethylene glycol (PEG) chains followed by complexation to Cu(II) ions. The resultant complex was applied as an efficient and strong recyclable homogeneous catalyst for the preparation of 1,8-dioxo-octahydroxanthenes under mild conditions. The homogeneous catalyst could be recovered and reused for several times.

    Keywords: Xanthene, Copper complex, Trans-esterification, Homogeneous catalyst