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Nanochemistry Research - Volume:9 Issue: 2, Spring 2024

Nanochemistry Research
Volume:9 Issue: 2, Spring 2024

  • تاریخ انتشار: 1403/02/23
  • تعداد عناوین: 8
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  • Mojgan Taebi, Mahnaz Amiri, Niloofar Rashidi, Mahsa Sistani, Sanaz Hadizadeh, Razieh Razavi *, Ali Reza Farzinnejad, Meysam Ahmadi Zeidabadi, Somayeh Karami Mohajeri Pages 77-90
    The utilization of silver nanoparticles (AgNPs) in diverse fields, including medicine, is on the rise, leading to the development of a non-toxic and environmentally friendly synthesis method. This study presents a straightforward and stable one-step synthesis of AgNPs using an aqueous extract of Amygdalus lycioides as both a reducing and stabilizing agent. The experimental findings demonstrated that the presence of Amygdalus lycioides extract results in the formation of AgNPs with smaller size, uniformity, and well-dispersed nanostructures. The synthesis process is significantly influenced by certain reaction parameters such as the molar ratio of AgNO3, temperature, and extract volume. Characterization of the nanostructures was performed using XRD, UV-Vis, FT-IR, DLS, and SEM measurements. Furthermore, the AgNPs exhibited potent antibacterial effects, leading to cell death through increasing the membrane permeability and disrupting bacterial wall integrity. Additionally, this research explores the fungicidal characteristics of the colloidal solution of nanosized silver as a potential antifungal treatment against various plant pathogens. Based on the obtained results, AgNPs exhibit varying levels of antifungal activity against these plant pathogens. Molecular docking calculations revealed the binding energy between Ag metal and bacteria. These findings pave the way for effective and novel antimicrobial therapies as alternatives to traditional antifungal and antibacterial drugs, thereby addressing the challenges of microbial resistance and the difficulty of eradicating infections in the near future.
    Keywords: Silver nanoparticle, Green synthesis, Antifungal Effect, Antibacterial Activity, Cytotoxicity, Herbal extract, Molecular docking
  • Mohammad Mahdi Safikhani, Azadeh Asefnejad *, Rouhollah Mehdinavaz Aghdam, Sadegh Rahmati Pages 91-102
    This research aimed to investigate the potential of combining tissue engineering with conventional treatment methods to address cardiovascular diseases (CVD). The study focused on designing and 3D printing polymeric scaffolds using a composition of sodium alginate/hyaluronic acid/gelatin (SA/HA/Gel), incorporating heparin as a cardiovascular drug. Scaffolds were printed at different angles (30°, 45°, 60°, and 90°) to assess their physical properties. Various analyses, including scanning electron microscopy (SEM), examined factors such as swelling, porosity, degradability, contact angle, and surface morphology. Chemical changes were evaluated using Fourier-transform infrared (FTIR) testing. Biocompatibility was assessed through cell adhesion and survival rate analyses using L929 cells. Results showed that higher contact angles increased porosity (42-60%) and improved mechanical properties (47 MPa to 85 MPa). Swelling and contact angle were minimally affected by the printing angle. The release model coefficients and diffusion coefficient varied with the contact angle, suggesting alterations in the drug release mechanism. The controlled release rate of heparin aligned with scaffold degradation, ensuring efficient delivery during tissue repair. Biological evaluation demonstrated satisfactory cell adhesion, biocompatibility, and absence of toxicity in the 3D-printed scaffolds. However, altering the printing angle could modify biological properties due to changes in scaffold characteristics. This study confirms that 3D-printed SA/HA/Gel scaffolds incorporating heparin exhibit desirable physicochemical and biological attributes, making them suitable for drug release systems in cardiovascular tissue applications.
    Keywords: 3D Printing, Scaffold, Drug release, Heparin, Heart tissue engineering Gelatin
  • Soheila Javadian *, Alireza Ramezani, S.Morteza Sadrpoor Pages 103-112
    The extracted crude typically contains water-in-oil (w/o) emulsions. In this regrd, a novel demulsifier was synthesized in this research through modifying silica with benzalkonium chloride (SBKC). This demulsifier serves as a low-cost and biodegradable solution for the treatment of w/o emulsions. The amphipathic demulsifier was characterized by various techniques such as scanning electron microscope (SEM) and X-ray diffraction (XRD). In addition, the effects of temperature, standing time, and optimal demulsifier dosage were systematically investigated. Silica was modified with varying contents of BKC. According to the bottle test results, SBKC-20 achieved complete water separation from crude oil in 50 minutes (compared to 75 minutes for pristine silica). The studies showed the considerable effect of temperature on demulsification efficiency, as SBKC-20 separated water in just 1 minute at 95°C. Interfacial tension (IFT), optical microscopy, and contact angle measurements were also employed to better understand the demulsification mechanism. The ability of SBKC-20 particles to penetrate the oil-water interface was confirmed by IFT and optical microscopy. For example, SBKC-20 decreased the IFT between water and crude oil from 18.6 to 6.9 mN.m-1.
    Keywords: Water in oil (w, o) emulsion, silica particles, demulsification, Surfactant
  • Yue Zhang, A.R.M Ariffin * Pages 113-137
    This study investigated the potential of retrofitting rainwater collection tanks (RWH) into the facades of student residential colleges to improve internal temperature control. Carbon nanomaterials, including carbon nanotubes (CNTs) and graphene, were incorporated into the RWH facades to enhance thermal conductivity and mechanical strength. The aim was to address urbanization and climate change challenges through passive cooling strategies. The study analyzed ambient temperature, relative humidity, and wall surface temperature based on heat transfer principles. Statistical attributes, such as maximum, minimum, and average values, as well as daily fluctuations were examined. Heat transmission from external to internal walls was also quantified.   Materials analysis in this study involved the utilization of X-ray diffraction (XRD) for phase analysis, scanning electron microscopy (SEM) for investigating the morphology of CNTs, and transmission electron microscopy (TEM) for further characterization. The results demonstrated the cooling effectiveness and thermal efficiency of the proposed RWH technology. The west-facing walls with RWH facades showed a remarkable cooling effect of up to 14.41°C compared to non-RWH counterparts. Similarly, east-facing walls equipped with RWH facades exhibited a maximum temperature reduction of 3.41°C. Carbon nanomaterials enhanced the structural integrity of the RWH facades, ensuring long-lasting reliability under challenging conditions. This study highlighted the effectiveness of RWH facades as passive cooling strategies for student residential colleges. The utilization of carbon nanomaterials further enhanced their thermal and mechanical properties. The results indicated valuable insights for improving internal temperature control and addressing climate change challenges in urban environments.
    Keywords: Retrofitting rainwater collection tanks, Internal temperature control, Passive cooling strategies Thermal efficiency, Energy
  • Mehdi Abdolmaleki * Pages 138-145
    In this work, we investigated the electrocatalytic activity of electrodeposited cobalt and CoMo alloy electrodes towards the oxidation of phenylhydrazine in 1 M sodium hydroxide aqueous solution. A previously proposed nontoxic tartrate electrolyte was employed to electrodeposit alloys. Electrochemical methods such as cyclic voltammetry (CV), chronoamperometry (CA), and electrochemical impedance spectroscopy (EIS) were used to study the electrooxidation of phenylhydrazine. When compared to pure cobalt electrodes, the voltammetric data for cobalt-molybdenum alloy electrodes indicated a lower peak potential and a higher peak current density. According to the EIS results, the polarization resistance of the Co-Mo alloy electrodes was much lower compared to the pure Co in 0.1 M phenylhydrazine basic solution. The CA results demonstrated that Co-Mo electrodes had greater stability than cobalt electrode. The Co-25 at % Mo and Co-33 at % Mo electrodes had higher catalytic activity among other synthesized electrodes for phenylhydrazine oxidation in an alkaline medium, the former being the best electrocatalysts for the phenylhydrazine electrooxidation.
    Keywords: Electrocatalytic properties, electrochemical impedance spectroscopy, Electronic effect, Nanostructured Co-Mo alloys, Phenylhydrazine electrooxidation
  • Farnaz Sadat Fattahi * Pages 146-152

    Gene therapy is a rapidly progressing field with vast prospective for fundamentally treating human diseases such as cancer, damaged tissues, and genetic syndromes. Between various approaches of gene delivery, there is a growing interest in oral administration of DNA as one of the safest and most straightforward methods. Nanoparticles are some of the important examples of nano-materials for molecule delivery (drugs, growth factors and DNA) used in biomedical applications. Several researchers have revealed the process of nanotechnology, specifically polymeric nanoparticles, as DNA delivery structures for transdermal routines. Polylactic acid (PLA) and its famous co-polymer polylactic-co-glycolic (PLGA) are biocompatible synthetic polymers widely used to produce nanoparticles. Biobased, biosourced, biodegradable biocompatible, and bioabsorbable polylactide nanoparticles are one of the most promising materials in gene therapy serving as DNA delivery vehicles. Polylactide nanoparticles are easily processable and undergo degradation into natural metabolites while matching its degradation rate with the healing time of damaged human tissues. This mini review presents the new developments in the applications of polylactide nanoparticles as DNA delivery systems. In addition, the release of DNA from these nanoplatforms will be reported briefly.

    Keywords: DNA, Polylactide, Gene delivery, Nanoparticle
  • Mostafa Yousefi, Younes Hanifehpour *, Mehdi Abdolmaleki, Negin Rahmani Pages 153-161
    In this research, tin sulfide compounds and their dope in different percentages with neodymium were prepared by the sonochemical method. Next, the surface and structure of the synthesized samples were thoroughly analyzed using different detection techniques such as scanning electron microscopy, X-ray energy scattering, X-ray photoelectron spectroscopy, and X-ray diffraction. The X-ray diffraction pattern showed that the crystalline phase of tin sulfide and its doping with neodymium was orthorhombic and the results of elemental analysis confirmed the presence of tin, sulfur, and neodymium elements. Based on SEM images, the morphology of the prepared SnS was crystalline and changed to a nanoflower structure after Nd doping. After examining the surface morphology and structure of the synthesized samples, diffuse reflectance spectroscopy (DRS) and 4-probe techniques were employed to study the optical properties and electrical conductivity of these compounds. Band gap calculations based on absorption spectrum data indicated that the band gap decreased with the increase in dopant amount. Additionally, with the increase in the amount of dopant and temperature, the electrical resistance declined and the electrical conductivity increased.
    Keywords: Tin sulfide, neodymium, Ultrasound-assisted, Bandgap, 4-probe, Diffuse reflectance spectroscopy
  • Aliakbar Dehno Khalaji * Pages 162-171
    In this work, α‑Fe2O3 nanoparticles were prepared by sonochemical‑assisted method along with calcination at two different temperatures 500 and 700°C for 3h. The α‑Fe2O3 nanoparticles were characterized by FT‑IR, XRD, VSM and TEM. All results show that the as‑prepared α‑Fe2O3 nanoparticles are of high purity with ferromagnetic behavior, uniform distribution, and low agglomeration. In addition, photocatalytic degradation of bisphenol A (BPA) was studied by α‑Fe2O3 nanoparticles at the presence of H2O2 as an electron trap. Photocatalytic results indicate that 98% and 90% of BPA with the initial concentration of 25 mg/L in the solution were degraded using 0.02 g α‑Fe2O3 nanoparticles within 330 min under the visible light irradiation.
    Keywords: α-Fe2O3, Sonochemical-assisted, Bisphenol A, Photocatalytic activity