مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران
سال شصت و هفتم شماره 5 (پیاپی 101، امرداد 1388)

Occult hepatitis B infection (OBI) is a form of hepatitis in which despite absence of detectable HBsAg, HBV-DNA is present in peripheral blood of patients. The responsible mechanisms for progression of OBI yet to be clarified, but some investigators believed that the genetics and immunological parameters are different in resistant individuals and patients. Vitamin D3 and its receptor interaction could be involved in anti-viral immune response. The aim of this study was to investigate the association between polymorphisms in intron 8 of VDR with OBI. In this experimental study, the plasma samples of 3700 blood donors were collected and tested for HBsAg and anti-HBs by ELISA

Learning and memory are the complicated agents of central nervous system that various regions of brain can be involved in these phenomena, especially regions like hippocamp. Various agents like nitric oxide and morphine can influence learning and memory. About the effects of morphine with other components there was not clear reports so in this study the effect of co-administration of L-Arginine (precursor of nitric oxide) and morphine in hippocampal CA3 area on spatial learning and memory in male rats was investigated

Gastric cancer is the second most common cancer and known as the second cause of death due to cancers worldwide. Adenocarcinoma is the most fatal cancer in Iran and a patient with this kind of cancer, has a lower lifetime than others. In this research, the survival of patients with gastric carcinoma who were registered at Taleghani Hospital, were studied. 291 patients with gastric carcinoma who had received care, chemotherapy or chemoradiotherapy, at Taleghani Hospital in Tehran from 2002 to 2007 were studied as a historical cohort. Their survival rates and its relationship with 12 risk factors were assessed. Of the 291 patients, 70.1 percent were men and others (29.9%) were women

Muscle weakness and fatigue are two factors that cause muscle injuries. The roll of motor control is important in regulation and reduction of this effect. Repetition of motion after muscle fatigue is due to the significant role of motor control system. The aim of this study was to evaluate the quality of roll control of central nervous system following fatigue in order to answer primary questions in therapeutic exercises. Twenty voluntary healthy subjects participated in this study. Dominant abductor policis brevis after surface electromyography (SEMG) of maximal voluntary contraction (MVC) fatigued by maximum three minutes isometric contraction in specific hand splint monitored by dynamometer until reduction of

The insertion depth of tracheal tube differs based on sex, age, position of head and neck, type of surgery, and anatomical consideration. The aim of this study was to determine the airway related distances in Iranian patients with a non-invasive, and accurate method, the computerized reconstruction of High Resolution CT (HRCT); Virtual Bronchoscopy. A total of 140 Iranian patients who became candidate for sinus and chest tomography, were enrolled in a cross- sectional study in Imam Khomeini Hospital Complex, Tehran, Iran, from 2006 to 2008. After reconstruction of airway related distances, Incisor- Vocal cord (IVD), Vocal cord- Carina (VCD) and Incisor- Carinal (ICD) Distances were determined

Surgical methods for treatment of tricuspid valve (TV) endocarditis include repair, replacement and partial or complete exicion. The aim of this study was to assess the results of these different techniques. Sixty seven patients were enrolled in this retrospective study. This study was carried-out between April 1997 and July 2007 in Imam Khomeini hospital. Decision of methods of choice for surgery was according to intraoperative findings. The mean age was 25.52±7.35 years and 74.36% were male. The most common bacteria was Staphylococcus areus (62.30%). Most of patients (74.60%) were IV drug abuser

Many studies have demonstrated that pre-term neonates gained more weight over the 10 days stimulation period. This research has been conducted to determine the effects of five days Tactile- Kinesthetic stimulation (TKS) on weight gaining of pre-term infants hospitalized in Fatemiye neonatal intensive care unit. Fifty one babies who graduated from the NICU to the intermediate care nursery were randomly allocated into test and control groups (24 and 27 neonate respectively). TKS was provided for three 20 minute periods per day for five consecutive days to the test group, with the massages

Kidney transplantation had been evaluated in some researches in Iran mainly with clinical approach. In this research we evaluated graft survival in kidney recipients and factors impacting on survival rate. Artificial neural networks have a good ability in modeling complex relationships, so we used this ability to demonstrate a model for prediction of 5yr graft survival after kidney transplantation. This retrospective study was done on 316 kidney transplants from 1984 through 2006 in Isfahan. Graft survival was calculated by Kaplan-meire method. Cox regression and artificial neural

Zinc is one of the elements necessary for growth and health in human. Some evidences indicate that zinc deficiency is one of real difficulties for the public health in both developed and developing countries. Since the pregnant women are more at risk of zinc deficiency, the objective of this study was to determine the rate of zinc deficiency in pregnant women in the 3 trimesters and to compare these data with that of the healthy controls. This research was an analytic- descriptive study which was done on 677 pregnant women in 3 Trimesters and 140 non pregnant groups who referred to clinic of Tehran University. Blood sample were taken And serum zinc was assessed By Enzymatic technique

Seroma formation, or the subcutaneous collection of fluid, is a common problem after surgery for the breast cancer. It may lead to wound-related complications and also can delay adjuvant therapy. The aim of this study was to investigate the effect of various clinical and therapeutic variables on seroma formation. A prospective cross sectional study of patients who underwent surgical therapy for breast cancer was carried out. Modified radical mastectomy was performed on 67 patients (65%) and 28 patients (27.2%) underwent breast conservative surgery. Simple extended mastectomy was done for the remaining 8 patients (7.8%).

Increased total plasma homocysteine (Hcy) is an accepted risk factor of cardiovascular disease (CVD), stroke, preclampsia, recurrent abortion and diabetes type I and II. The aim of the current study was to assess serum homocysteine and its relation with serum folat, vitamine B12 and lipid profile in gestational diabetes mellitus and to compare these with those of pregnant women. In a prospective controlled survey 80 pregnant women (24-28 weeks) with uncomplicated pregnancies were evaluated. They were assigned to one of two groups according to the results of 100g-OGTT. In the case group there were pregnant women with gestational diabetes mellitus according to the OGTT

Iranian researchers and scientists in the fields of psychiatry and psychology undoubtedly need to spend more time and make considerable efforts to prepare and validate Persian versions of measurements. The present study was designed to validate HADS in Iranian clinically anxious and depressed patients compared to normal population. 261 anxious and depressed patients referred to the inpatient clinic of Rouzbeh Psychiatric Hospital, Tehran, and 261 healthy volunteers (matched for their sex) were tested using HADS, and two additional clinical tools, ie., BDI & BAI. Then the patients