مجله دانشگاه علوم پزشکی گرگان
سال دوازدهم شماره 3 (پیاپی 35، پاییز 1389)

Post dural puncture headache (PDPH) is a relatively common complication in spinal anesthesia. Several regimens had explained for treatment of this problem. The aim of this study was to determine the effect of intravenous single dose of Aminophylline (1.5mg/kg/body weight) on the incidence of PDPH in cesarean section under spinal anesthesia.

In a double blind randomized trial study, 120 patients undergone spinal anesthesia for the elective cesarean section in Motahhari hospital of Marvdasht in Fars province in south of Iran during 2008. After umbilical cord clamping 1.5mg/kg/body weight of Aminophylline injected slowly and intravenously in 60 patients. In placebo group (n=60) normal saline injected intravenously. At the 1st, 4th, 24th and 48th hour after surgery, PDPH in patients were evaluated.

The incidence of PDPH was significantly lower in cases compared with controls during the first 24 hours post operation (5% vs. 31.7%, P<0.001). Incidence of PDPH in case and control groups after 48 hours was 5% and 23.3% respectively (P<0.004).

This study revealed that the intravenous single dose of Aminophylline (1.5mg/kg/body weight) significantly reduced PDPH after spinal anesthesia in cesarean section

Lichen planus presents with chronic, inflammatory mucocutaneous lesions; with almost 1-2% prevalency without any relation to demographic variables. This study was done to describe the clinical pathologic features of lichen planus patients in Mashhad, Iran.

In this descriptive study, demographic data (age and sex) and some factors such as histology, form and anatomical zone of lesions were recruited from patient’s medical records and pathological slides revised. Data analyzed by using SPSS-13 software and chi-square and T student tests.

309 patients (177 male, 132 female) were enrolled. Mean age was 40.12±16.3 years-old and patients were categorized mostly in 41-50 years age group. Clinical presentation in 44% was plaque and 41.7% with papules, 23.9% hyper pigmented, 26.9% scaled, 4.9% annular form and 2.9% linear. 45.6% of patients had classic histo-morphology and 25.9% of them had hypertrophic form. There was not any relationship between lesion histopathology with either sex or age. Anatomical zone had a significant relation with histopathology of lesion (P<0.05).

This study showed that the prevalence of genital and mucousal lesions was lower than reported in other studies in various parts of the world.

Helicobacter pylori (H.pylori) with positive Cytotoxin associated Gene A (CagA) have higher potential for pathogenesis. Cytotoxin associated Gene A (CagA) accelerate the pathogenecity of bacteria due to cytotoxin production stimulation. The aim of this study was to determine the prevalence of the anti-CagA antibody among H. pylori infected persons in Golestan province-North of Iran.

This descriptive study was carried out on 676 H. pylori positive subjects in Golestan province, northern Iran during 2008. Anti CagA antibody were determined in H.pylori positive subjects. Data analyzed by SPSS-16 software and chi-square test.

Prevalence of anti CagA in Helicobacter pylori infected cases was 57.7% (390 cases: 179 males and 211 females) (95% CI: 53.9-61.4). According to age the highest and lowest cases of anti CagA antibody were seen in, 15-24 (63.4%) and under 5 years old (26.3%). The level of anti CagA antibody in Sistanian ethnicity group (67.2%) was more than other ethnic group. Anti CagA antibody in Rural area was more than urban regions. Sero prevalence of anti CagA antibody was highest in Minudasht twon (78%), located in East of province in comparison with Bandar Gaz (44%) in west of province.

This study showed the prevalence of CagA positive Helicobacter pylori strains in this region is similar to other regions of Iran, Asia and Europe and higher than African population.

Adolescence is a critical period which has physical, sexual and psychosocial changes. Scientists believe that adolescent must aware from necessary knowledge at critical time, because unawareness causes more sexual deviation. Thus in this study parents and teacher's view had been assessed about the best time and appropriate method for reproductive health education for female adolescents.

In this descriptive study 400 parents and 50 teachers from girl's high school were chosen by multiple sampling in Gorgan-Iran. Information collected by a questionnaire which consisted of two parts of demographic characteristics and polling which contains three parts: fertilization and pregnancy, family planning, HIV and STDs. Descriptive statistic was used for analysis the Data by SPSS-9 software.

43.5% of mothers and 38.5% of fathers believed that the best time for fertilization and pregnancy education is at marriage time, and 46% of teachers believed grade III high school and pre- university is suitable time. Majority of teachers and parents believed that the best time to teach family planning is at marriage time. 32% of mothers believed that the most suitable time. for teaching HIV and STDs is grade 3 at high school and pre- university but about 30.7% of fathers and 38% of teachers noted the best time is grade I and II at high school. About the most suitable education method, 45% of mothers and 44% of teachers believed that attending a midwife at school is necessary.

This study showed that majority of parents and teachers agree with reproductive health education during high school and marriage time and they mentioned that the best education method should be done at school with attending a midwife as a counselor.