مجله دانشگاه علوم پزشکی رفسنجان
سال یازدهم شماره 5 (پیاپی 46، آذر و دی 1391)

Given the vital role of scientific journals in dissemination of knowledge especially within the health domain، correctly managing them is very important. The aim of the present study was to determine the fate of rejected articles by Rafsanjan University of Medical Sciences Journal (RUMSJ). In this follow up study، the fate of all rejected manuscripts during 2001 till 2007 was determined. In order to do that، three SID، Magiran، and IranMedex databases were searched using the titles and the names of the authors of each manuscript. During the years of the investigation، 1030 articles were submitted to the journal and after primary review، in the end 512 (49. 7%) of them were rejected. Out of these، 155 (30. 3%) have been published in other related journals. The titles of 96 (61. 9%) of published articles had slightly been changed. Twelve (7. 7%) of these articles were published before submission to JRUMS. Considerring the fact that over 70 percent of the manuscripts which were rejected by RUMSJ have not been published anywhere else، it could be concluded that this journal has functined reasonably well in the primary evaluation of the manuscripts.

Serotonergic system has a role in procedure of morphine dependence and withdrawal signs incidence. On the other hand it has been shown that antidepressants may reduce the abuse susceptibility of opioids. So، the aim of this study was to investigate the effect of citalopram as a selective serotonin reuptake inhibitor (SSRIs) antidepressant on morphine withdrawal signs in male mice. In this experimental study forty male NMRI mice (20-30 g) were used. Morphine dependency was induced using a four- day schedule method with 50، 50، 75 and 50 mg/kg dosing respectively. In the fourth day 2 hours after single dose of morphine، naloxone was injected (5 mg/kg) and withdrawal signs were recorded with number of jumping and diarrhea، grooming، wet dog shake، teeth chattering، writing، climbing based on the scores of 0 to 3 for 30min. Treatment group received different doses of citalopram (5، 10 and 20 mg/kg; Intraperitoneally). Different doses of citalopram dose-dependently and significantly decreased the morphine withdrawal signs (except diarrhea) in the experimental group. (p<0. 05 and p<0. 001)). The present study is in accordance with other reports indicated that 5-HT enhancing agents (e. g. SSRIs) may be promising treatments for morphine withdrawal signs.

Prescription is one of the most important phases of medication use and so much so that it could be said that high quality of prescription overall indicates high quality of care. The most frequent number of medication errors occurs during drug prescription which leads to patient injury or death in the hospitals. Present study was carried out to evaluate the prescription quality of medication chart of hospitalized patients in Rafsanjan hospitals، 2007. This descriptive cross sectional study was conducted in three months during the year 2007. Drug order sheets of 800 patients from 20 wards were studied by systematic randomized sampling. Data were collected using a researcher made check list، include demographic characteristics of physicians and 18 items related to quality of medication chart and medication related indicators. Data were analyzed using the SPSS version 18 software. The mean score of total of checklists was 12. 3±2. 84 which indicated desirable conditions. Mean score of medication chart related indicators was 3. 49 ± 0. 74 which showed desirable status. Patient allergies were not recorded. Medication related indicators mean score was 8. 89 ± 2. 4 which shows semi desirable status. Based on the findings، observance of prescription standards such as legibly writing of drug order، documentation of patient allergies، drug preparation and its special precaution had undesirable status which are potential risk factors for medication errors.

Nowadays، researchers regard sport as one of the reinforcing methods to the growth of psychological dimensions. The objective of the present study was to examine the role of hardiness and forgiveness in predicting hope among athletes. This descriptive-analytic type of correlation study was carried out on and the 60 athletic students (30 males and 30 females) from Mohaghgh Ardabil University who voluntarily participated in the study and answered Snyder hope scale، Ahvaz hardiness scale and Walker and Garsokh forgiveness scale. The data collected from the sample were analyzed using the statistical methods of correlation and regression. Subjects mean age was 20. 65±1/83 year. The obtained results revealed that hope positively correlated with hardiness (r= 0. 54) and with forgiveness (r= 0. 50). Also، hardiness positively and significantly (p=0. 001، R2= 0. 34) predicted the changes related to hope. This study indicated that from two variables of hardiness and forgiveness، personality construct of hardiness can predict changes of hope in athletes.

Food is very important for health and treatment. The inctease of food residuals specially in hospitals can lead to the decreas of food intake and also increase cost the of treatment and hospitalization. The goal of this study was to determine the effect of food services training on amount of food residual in Tehran Boali Hospital to improve hospital catering. This Research was a practical and semi-experimental study. All of the food staff (15 persons) were trained in the form of direct teaching by using educational pamphlets about food services. To determine the food service situation and assess the amount of food residual the study was performed on 130 persons (in-patients and personnel). The other tools of this study were satisfaction questioner and food residual observational checklist. To compare the amount of food residual before and after training paired t-test was applied. Most of the participants were dissatisfied with food services and significant differences were shown between the amount of food residual befor and after personel training (t=-5.36 p=0.001). The average amount of food remaining at breakfast from 1.8 in pre-teaching was deacrease to 0.7 and at lunch from 2.09 to 1.89 and in dinner time from 2.2 to 1.6 reduced. It seems that educational planning for personels can indicated and raise their knowledg about their duties and their weaknesses and Strengths to improve quality performance which will lead to customer satisfaction and hospital profitability.

Retinoic acid has a major role in a variety of biological processes including growth and differentiation. One of these effects is epithelialization seen in blastema tissue exposed to different concentration of retinoic acid، due to its embryo-like cells. The main objective of this research was to investigate an experimental studies of employed different concentration of retinoic acid on embryonic- like tissue as an experimental model in vitro. This research is interventional study. The blastema tissue was prepared as the rings by punching pinna of New Zealand white rabbits with professional ethics. Then blastema tissues were cultured with different dose of retinoic acid (10-5 µl/ml، 10-4 µl/ml، 10-3 µl/ml) and evaluated in days of 3، 7، 14، 21 and 28 by histotechniques such as hematoxylin and eosin and Masson''s trichrome staining. The results showed that epithelialization process occurs at the day of 14 in control specimen (without retinoic acid) but samples treated with RA in concentration of 10-5 µl/ml show increases in epithelialization. Cell death was seen with concentration of 10-3 µl/ml. Results revealed that retinoic acid has an effect on epithelialization of dynamic tissues such as blastema which has an embryonic- like cells and tissues properties.

Zymosan is the name given to a yeast cell wall fraction having the specific immunomodulatoryl property، e. g stimulation of phagocytosis and reticuloendothelial system. Interest in this fraction is derived from positive results of zymosan administration. Recently zymosan has been used more fragmentaly in various clinical investigation، for example in transplantation and autoimmunity disease. Our aim was to find a rapid and new procedure for isolation of zymosan from candida abicans cell wall. In this laboratory study، Candida albicans was cultured on GYEP Yeast and harvested،then Cell wall of the yeast candida albicans after disintegration، centrifugation and repeat washing were suspended in 0. 5m Na2Hpo4، as a %5 of suspension. The suspension was boiled for 3h، purified by repeated washing with water and ethanol. Finaly the product was freeze deried. Zymosan purification was confirmed using complement fixation test، LAL test and SDS-PAGE. The yield of zymosan was about 1. 8 percent of original yeast by dry weight. This yeast fraction had property of inactivating the complement. Result of L. A. L test have demonstrated that zymosan product had glucan. also zymosan bound was deteced. This study suggested that this method is fast and usefull (in comparison to Saccharomyces Cervisiae) for preparation of zymosan from candida albians cell wall. Regarding to the results of complement fixtion test، the zymosan was preserved its biological properties.

With no cure or effective vaccine، education is the only means of controlling AIDS. Barbers and beauticians can play an effective role for preventing and controling disease. Therefore this study has been done to determine the knowledge and attitude of Birjand barbers and beauticians about AIDS. This quasi experimental (before-after study design) study was performed on Birjand ''barbers and beauticians. After assessment Validity and calculating Cronbach''s α coefficient، the level of knowledge and attitude was evaluated first by using a questionnaire. Educational program was performed in the health centers. After one month knowledge and attitude was determined again and then was compared with pretest information. Data was analyzed by Independet and paired T tests and ANOVA test. From a total of 123 barbers and beauticians with mean age (31. 4 ± 8. 5) 23 were males and 100 were females. After the education the mean scale of knowledge was increased from 28. 2 ± 7. 8 to 38. 1 ± 6. 2 (p=0. 001) and attitude from 53. 7 ± 7. 8 to 57. 6 ± 6. 7 (p=0. 001) respectively. Before intervention 20. 3% of samples had good knowledge and 22. 7% of them had positive attitude about AIDS. Which after the intervention was increased to 73. 2% and 39% respectively (p=0. 001). The results of the Study indicated that health education program was effective in promotion of the positive knowledge and attitude of the barbers and beauticians. Educational programs should be considered by health mangers to increase the knowledge of the beauticians and barbers about contagiouse disease especially AIDS.

Many people have a kind of obsession with their appearance. If the concerns are causing severe damage to the social functions، occupational and other aspects of life it is diagnosed as body dysmorphic disorder. This study investigates the relationship between obsessive - compulsive disorder and body dysmorphic disorder in a nonclinical female samples in the year 2007. In this descriptive study، female students of medical sciences in Tehran participated and using SPss software، using Chi square test، Mann-Whitney Test and Fisher test were examined. The study involved 456 female students 18 to 26. Mean age was 20. 5±1. 8. The results showed a significant correlation between BDD and OCD. (p=0. 031) Given the significant prevalence of symptoms of BDD in this study، screening for this disorder in high-risk groups reduces many costs resulting from inappropriate treatments. Chance of body dysmorphic disorder symptoms in those with symptoms of obsessive - compulsive was 3. 5 times more than the people without symptoms of the disorder، suggests the obcessive nature of body dysmorphic disorder in the study group.

Central giant cell granuloma formerly called «giant cell reparative granuloma،» is a non-neoplastic lesion. Some lesions demonstrate aggressive behaviors similar to that of a neoplasm. The mandibular / maxillary ratio has been reported as being from 2:1 to 3:1. Lesions are more common in the anterior portions of the jaws An 11-year old girl was referred with a chief complaint of chin expansion without pain. The radiographic exam ination showed a multilocular radiolucent lesion extended to lower border of the mandible. The histopathological examination showed a highly vascularized fibrous stroma with several multinucleated giant cells. Because of size of lesion، surgical approach was preferred. Most giant cell granulomas of the jaws are asymptomatic and usually first come to attention during a routine radiographic examination or as a result of painless expansion of the affected bone. So early diagnosis is very important in the prognosis.