مجله زنان مامائی و نازائی ایران
سال شانزدهم شماره 56 (هفته دوم تیر 1392)

Nausea and vomiting are the second most common complaints reported in the postoperative period and can lead to rare but serious medical complications. The aim of this study was better prevention of postoperative nausea and vomiting following gynecologic laparoscopic surgeries. This clinical trial was done in Qhaem and Emam Reza hospital of Mashhad، Iran during 2010 and 2012. 150 patients who were candidate for gynecologic laparoscopic surgeries were divided randomly into three groups. All patients received Dexamethasone immediately after anesthesia. 15 minutes before extubation، one group were given Granisotron and second group were given Ondostron and the third group (control) were given normal saline as placebo. The patients who had postoperative nausea and vomiting were treated with the same antiemetic drugs that they were given preopertively but with reduced dose of 25%. All patients were assessed for signs of nausea and vomiting. Data were analyzed using SPSS software version 11 and one-sample kolmogorov-Smirnov، one-way ANOVA and Kruskal-Wallis tests. P value less than 0. 05 was considered significant. Vomiting in the first one hour and 1-6 hours after operation was more in Granisetron-Dexamethasone group than Ondansetron-Dexamethasone group. The difference was statistically significant between two groups (p<0. 019) and the difference of vomiting was statistically significant between two groups and control group (p<0. 045) Granisetron-Dexamethasone is more effective than Ondansetron-Dexamethasone and or placebo in control of postoperative nausea and vomiting after gynecologic laparoscopic surgeries، 1 hour and 1-6 hours after operation. It is recommended to use these drugs pre-operatively.

Premenstrual Syndrome (PMS) is a common disorder in women that causes emotional، physical and behavioral dysfunctions، particularly in their family relationships، social and educational activities. Because of researchers are interested to identify factors associated with PMS، this study was done to determine the relationship between PMS and personality type in female students of Bushehr Universities.

In this cross-sectional study، 478 female students of Bushehr University of Medical Sciences and Persian Gulf University were selected through census sampling in 2011. A series of valid and reliable questionnaire include “type A and B personality questionnaire” and an instrument for assess PMS symptom were used for data collection. Data were analyzed using SPSS software version 15 and descriptive statistics tests، chi-square and ANOVA tests. P value less than 0. 05 was considered significant.

Moderate to severe Premenstrual Syndrome was reported in 92 students (32%) of Medical Sciences University and in 66 students (34. 8%) of Persian Gulf University. 237 students (85. 5%) with type A personality and 177 students (88%) with type B personality had PMS. Severity of syndrome in students with type B personality was significantly higher than students with type A personality (p<0. 02).

The severity of PMS is different in types A and B personality. The results of the study indicated that identifying personality characteristics should be considered in women’s health planning and dealing with them during PMS.

Hypericum perforatum is one of the most commonly used herbal drugs which is traditionally used in many cases including treatment of bacterial vaginosis. Although in-vitro studies indicate a strong antibacterial activity of Hypericum perforatum، no study was found regarding its effects on bacterial infections in human. Therefore، this study was done to determine the effect of hypericum perforatum vaginal gel in treatment of bacterial vaginosis.

This pre- and post-test single group interventional study was conducted on 82 married women with bacterial vaginosis who were not suffered from other vaginal infections and referred to Jolfa and Hadishahr cities of Azarbayjan Sharghi، Iran، during March 2012 to November 2012. They got 5 gr of hypericum perforatum vaginal gel 3% daily for 5 days. Participants were evaluated before and 10-12 days after starting the treatment and patient complaints، clinical signs and Amsel criteria were assessed. Data were analyzed using SPSS software version 13 and McNemar test. P value less than 0. 05 was considered significant.

67 participants (82%) were cured 10-12 days after treatment. The most common complaints of participants at baseline were malodorous discharge (94%)، vaginal burning during couitus (45%)، vaginal itching (40%) and lower abdominal pain (35%). 10-12 days after treatment، frequency of the complaints were reduced to 4%، 8%، 5% and 11%، respectively (p<0. 001). 11 women (13%) had reported experience of mild vaginal burning that had not resulted in cessation of drug use.

Hypericum perforatum vaginal gel has high efficacy in treatment of bacterial vaginosis، reduction in patients complaints and improvement of the Amsel criteria and can use as an alternative treatment in drug resistance and herbal treatment.