فهرست مطالب

Nephro-Urology Monthly - Volume:7 Issue: 1, Jan 2015

Nephro-Urology Monthly
Volume:7 Issue: 1, Jan 2015

  • تاریخ انتشار: 1393/10/12
  • تعداد عناوین: 10
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  • Kaushal Kumar *, Ahsan Ahmad, Mahendra Singh, Amit Kumar, Rana Pratap Singh, Mumtaz Hussain Page 21736
    Introduction
    Renal lymphangiectasia is a rare disorder of the lymphatic system that might be confused with various other renal cystic diseases and urinoma. Clinical presentation is non-specific and characteristic findings in radiologic imaging are the mainstay of diagnosis..
    Case Presentation
    We reported a case of bilateral lymphangiectasia in a 32-year-old woman who presented with flank pain and hypertension..
    Discussion
    Renal lymphangiectasia is an uncommon benign condition. Most of the cases improve with conservative treatment. Surgery is rarely required, except in cases such as those with persistent pain refractory to medication..
    Keywords: Renal lymphangiectasia, Cyst, benign
  • Santosh Kumar *, Kumar Jayant Page 22297
    Introduction
    Here we report an unusual case of massive stone formation in augmented urinary bladder..
    Case Presentation
    A 25-year-old man presented with recurrent urinary tract infection ten years after augmentation cystoplasty after a complex pelvic fracture urethral distraction defect. On evaluation by ultrasonography, X-ray, and computed tomography of abdomen showed large burden of stones in the urinary bladder. Patent underwent an open cystolithotomy and forty stones weighing about 1400 g were removed. It was one of the largest reported stone burdens following augmented cystoplasty until now..
    Discussion
    Even though stone formation is a common complication after augmentation cystoplasty, it can be prevented by regular bladder wash and good follow-up..
    Keywords: Vesical Calculus, Augmentation Cystoplasty, Cystolithotomy
  • Mohammad Reza Ardalan * Page 22653
    Context: Renal Transplantation is the most effective treatment for patients with end-stage renal disease, which is fortunately available in the developing countries, even for poor people. Nonetheless, the way forward should be the implementation of advanced science of transplantation, allograft monitoring abilities, knowledge about the epidemiology of renal disease in any specific region, awareness about the influence of ethenic and genetic factors immunosuppressant bioavailability, and post-transplant complications all strongly affecting the patients and allograft survival..Evidence Acquisitions: In this process we searched mainly in PubMed, Web of Science and Google Scholar data bases for key words of renal allograft monitoring, post-transplant infections, renal/kidney transplantation and Iran. We followed the cross articles to follow our main idea to find a connection between modern advancement in renal allograft monitoring and our practice in developing countries. Another focus was on the special infectious and non-infection complication that do exist in specific region and need specific considerations..
    Results
    Implementation of modern techniques of immune monitoring, allograft function, awareness about the specific infectious and non-infectious disease in each region improves the quality of renal transplantation..
    Conclusions
    We need to combine the advance scientific vision with local vigilance to achieve the best outcome in renal allograft recipients.
    Keywords: Transplantation, Tissue Donors, Antibodies, MicroRNAs
  • Santosh Kumar *, Kumar Jayant, Seema Prasad, Swati Agrawal, Kalpesh Mahesh Parmar, Rajesh Roat, Kushal Kumar Page 22671
    Introduction
    Adrenal Myelolipoma is a rare benign neoplasm, which contains mature adipose tissue and variable amounts of haematopoietic elements. Most lesions are small and asymptomatic, discovered incidentally during autopsy or imaging studies performed for other reasons..
    Case Presentation
    Here we reported a series of two cases of giant myelolipomas of the adrenal gland; first one the largest tumor reported so far presented with massive hemorrhage and the second case introduced with its rare unreported presentation of adrenal myelolipomas i.e. a large abscess..
    Discussion
    Adrenal myelolipoma is a rare and asymptomatic tumor usually discovered incidentally in less than 1% of population on autopsy or imaging performed for other reasons. There is an increasing incidence of large adrenal myelolipoma (> 10 cm) presenting with life threatening and recurrent retroperitoneal hemorrhage along with other complications as abscess. To avoid such a life-threatening situation, authors recommend close monitoring and consideration of urgent surgical intervention for tumors larger than 4 cm at presentation or increase in size or change in appearance during follow-up..
    Keywords: Myelolipoma, Hemorrhage, Abscess
  • Amitis Ramezani, Mohammad Reza Aghasadeghi, Farrokhlagha Ahmadi, Effat Razeghi, Ali Eslamifar, Mohammad Banifazl, Masoomeh Sofian, Golnaz Bahramali, Soheila Hekmat, Arezoo Aghakhani * Page 22674
    Background
    Occult Hepatitis B virus (HBV) infection (OBI) is defined as the presence of HBV-DNA in the liver or serum with undetectable hepatitis B surface antigen (HBsAg). Hemodialysis (HD) patients are at risk of acquiring parenterally transmitted infections..
    Objectives
    The aim of this study was to assess the prevalence of OBI in HD patients..Patients and
    Methods
    A hundred HBsAg negative HD patients were included in this study from main dialysis units in Tehran, Iran. HBsAg, hepatitis B surface antibody (anti-HBs), hepatitis B core antibody (anti-HBc) and liver enzymes levels were examined in all subjects. The presence of HBV-DNA was determined in plasma samples using real-time PCR..
    Results
    A hundredpatients with a mean age of 58.5 ± 16.1 years were enrolled in this study. In total, 56.7% were male and 43.3% female. Anti-HBs, anti-HBc, anti-HCV and anti-HIV were detected in 56.7%, 2%, 5.2% and 1% of patients, respectively. Isolated anti-HBc was detected in 2% of cases. HBV-DNA was detected in 1% of HBsAg negative patients..
    Conclusions
    This study showed a low rate of isolated anti-HBc and occult HBV infection in HD patients. It can be due to improvement of people’s knowledge about HBV transmission routes, HBV vaccination of HD patients and regular surveillance of HBV infection..
    Keywords: Hepatitis B virus_Hemodialysis_Infection
  • Mohammad Nassaji *, Raheb Ghorbani, Mohammad Reza Tamadon, Masomeh Bitaraf Page 22712
    Background
    Overweight and obesity have become a global public health over the last decades. Obesity has been suggested to be a risk factor for some infections, but studies often showed controversial findings. Few studies examined the relationship between body mass index (BMI) and urinary tract infection (UTI), showing inconsistent results..
    Objectives
    The purpose of this study was to determine the relationship between BMI and UTI in adult patients..Patients and
    Methods
    Adult patients (≥ 18 years old) who were referred to clinics or admitted in hospital with diagnosis of UTI were considered for participation in the study. Control group were selected from healthy adult normal population whom underwent medical check-ups at the same hospital and without history of UTI. Data about age, gender, history of diabetes mellitus and BMI were registered for individuals who met inclusion criteria..
    Results
    A total of 116 patients with UTI and 156 people as the control group were included in the study. Two groups were matched for age, gender and history of diabetes mellitus. Mean BMI ± SD of patients was 25.2 ± 4.0 kg/m2 and the controls was 25.1 ± 3.6 kg/m2. There was no significant correlation between BMI and UTI (P = 0.757). Mean BMI ± SD of patients with upper UTI was 25.6 ± 4.1 kg/m2 and for lower UTI was 24.9 ± 4.0 kg/m2. There was no significant difference between BMI of controls and patients with any type of UTI (P = 0.573)..
    Conclusions
    Our findings did not found an association between BMI and UTI and does not support obesity as a risk factor for UTI in adult patients..
    Keywords: Urinary Tract Infection, Body Mass Index, Patients
  • Hadi Zamanian, Zahra Taheri Kharameh * Page 23152
    Background
    Hemodialysis patients have a high physical and psychosocial symptom burden. There is no valid and reliable tool for assessing symptoms of hemodialysis patients in Iran..
    Objectives
    The aim of this study was to determine psychometric properties of the Persian version of the dialysis symptom index (DSI)..Patients and
    Methods
    The forward-backward procedure was applied to translate the DSI from English into Persian (Iranian language). The scale (Persian Version) was tested with a convenience sample of 95 patients with end-stage renal disease referred to main hemodialysis centers from December 2012 to June 2013. Validity was assessed using content, face and convergent validity. To test reliability, the kappa values were calculated for test-retest stability and the Cronbach alpha coefficients were also calculated for internal consistency..
    Results
    The mean age of patients was 50.4 (SD = 15.72) years and % 61.1 of patients were male. The most commonly reported symptoms were fatigue, being irritable and nervous. Divergent validity was mostly supported by the pattern of association between DSI and SF-36 (r = -0.18– -0.48, P< 0.05). Cronbach’s alpha of the DSI was 0.90 and the weighted kappa ranged from 0.21 to 0.93, and it was greater than 0.4 for 25 of the 30 items..
    Conclusions
    The Iranian version of the DSI had good psychometric properties and can be used to assess symptoms of hemodialysis patients..
    Keywords: Dialysis, Hemodialysis, Patients
  • Omid Sedighi, Saeid Abediankenari *, Batoul Omranifar Page 23563
    Background
    Beta-2 microglobulin (B2M) is considered as a surrogate marker for middle molecule uremic toxins and a key component in dialysis-related amyloidosis. However, few studies have evaluated role of B2M in patients with chronic kidney disease (CKD)..
    Objectives
    The purpose of this study was to evaluate the association of plasma B2M level with some metabolic and cardiac performance factors in patients with CKD..Patients and
    Methods
    In this case-control study, we measured plasma B2M level in 86 patients with different stages of CKD and 78 age- and sex-matched individuals, as healthy control group. Then we investigated the association between plasma B2M level and left ventricular hypertrophy, ejection fraction (EF), and left ventricular end-diastolic diameter (LVEDD) in echocardiography and some inflammatory and metabolic factors in patients with CKD..
    Results
    Mean plasma B2M level was significantly higher in patients with CKD than in control group (P < 0.001). It was directly correlated with serum C-reactive protein (r = 0.167, P < 0.001), phosphate (r = 0.112, P < 0.001) levels, and left ventricular mass index (r = 0.438, P < 0.001) and LVEDD (r = 0.275, P < 0.001) in echocardiography. It was also inversely correlated with glomerular filtration rate (r = -0.033, P < 0.001), albumin (r = -0.521, P < 0.001), hemoglobin (r = -0.748, P < 0.001), and EF (r = -0.625, P < 0.001)..
    Conclusions
    Our findings suggested that plasma B2M level is inversely associated with GFR and EF and directly correlated with some metabolic and cardiac performance factors..
    Keywords: Chronic Kidney Disease, Cardiovascular Disease
  • Behzad Einollahi, Mohsen Motalebi *, Zohreh Rostami, Eghlim Nemati, Mahmood Salesi Page 23849
    Background
    Sleep disorders are prevalent complication in patients with end-stage renal disease undergoing hemodialysis (HD). The factors affecting sleep quality (SQ) of patients on HD have not been completely recognized yet. In addition, some studies have shown that poor SQ increases the risk of mortality in patients on HD..
    Objectives
    This study aimed to identify the prevalence of poor SQ and its associated risk factors in Iranian patients on HD..Patients and
    Methods
    This cross-sectional and multicenter study was conducted on 6878 patients on HD from 132 dialysis centers in Iran. Sleep domain of disease specific core of KDCS-SF questionnaire and generic core of this questionnaire (SF-36) were used to assess patients’ SQ and quality of life (QoL), respectively. A poor SQ was defined as a score of ≤ 61.2. Logistic and linear regression analyses were applied to assess predictors of SQ and their associations..
    Results
    The mean age of patients was 54.4 ± 17.1 years and 39.7% of patients were > 60 years old. The majority of our patients had poor SQ (60.6%). Patients with diabetes mellitus were significantly more likely to have poor quality of sleep (63.4%). In logistic regression analysis, there were significant correlation between good SQ and younger age, shorter dialysis vintage, less muscle cramp, high QoL, high cognitive function score, and high sexual function. In addition, linear regression showed a significant association among SQ, QoL, and hospital stay as an outcome..
    Conclusions
    With improving some factors and QoL of patients on HD, we can promote SQ in these patients that it might lead to reduction in length of hospital stay..
    Keywords: Sleep, Quality of Life, Hospitalization, Questionnaire
  • Arash Dehghan, Ghazal Sami *, Nika Eskandari Page 24308
    Introduction
    Leiomyosarcoma is a malignant soft tissue tumor that can arise from any tissue containing smooth muscle. Leiomyosarcomas of the spermatic cord are rare tumors of non-testicular origin, which drain into the retroperitoneal lymph nodes and have been reported in less than 150 cases in the literature until now. Radical inguinal orchiectomy and high ligation of the cord is the standard primary surgical procedure in spermatic cord leiomyosarcoma..
    Case Presentation
    Here we reported a 75-year-old man who presented with a painless lump in the right hemiscrotum. A right radical orchiectomy was performed. Histopathology confirmed a neoplastic tissue with mesenchymal origin in spermatic cord; further evaluation revealed a leiomyosarcoma of the spermatic cord. The patient was followed up for 1-year and shows no signs of recurrence.
    Conclusions
    Preoperative diagnosis of spermatic cord leiomyosarcma is difficult and commonly made by histological examination and immunochemical staining..
    Keywords: Urologic neoplasms, Leiomyosarcoma, Spermatic Cord