فصلنامه طب مکمل
سال چهارم شماره 4 (پیاپی 13، زمستان 1393)

Premenstrual syndrome is the most common disorder in women of reproductive age. The causes of the premenstrual syndrome have not been clearly elucidated. In this regard، different methods have been suggested and one of them is traditional use of medicinal herbs. This study was aimed to assess the effect of valerian on severity of psychological and behavioral symptoms of premenstrual syndrome. In this double blind clinical trial، 120 students with premenstrual syndrome were randomly assigned to either the intervention or placebo groups. Subjects intervention group were received valerian capsule (530 mg Valerian root) twice a day for 2 months continuously. The control group received placebo capsule (50 mg of carbohydrate) using a similar protocol. Data collection was done via Dickerson questionnaire and the severity of premenstrual syndrome was detected before the intervention and it was compared with1 and 2 months after the intervention conditions. Data was analyzed with SPSS 22 software. Data showed that there were no significant differences between the two groups before intervention but 1 and 2 months after taking valerian capsules، the severity of psychological and behavioral symptoms was significantly lower than the control group (p<0. 00). Valerian significantly reduced the severity of psychological and behavioral symptoms in premenstrual syndrome. Therefore، its use is recommended for Premenstrual syndrome.

Angiogenesis, is an important process in physiological and pathological conditions as tumor growth and metastasis. Therefore, combinations that lead to inhibit angiogenesis may develop as an anti-cancer drug. In the present research, the anti-angiogenesis effect of Licorice root extract and Glycyrrhizic acid in Chorioallantoic membrane is investigated. In this experimental study, 45 ROSS fertilized eggs were randomly divided into three groups, Control, experimental 1 and 2. On the eighth day, Chorioallantoic membrane was soaked in control group with DMSO, in the first experimental group with extract of licorice and in the secondth, with Glycyrrhizic acid. Twelfth day photographed from samples whit using of photosteriomicroscope, the number, and length of vessels measured, also Drabkin test was performed to estimate the vessel density. Obtained data were analyzed by t-test (P<0.05). The mean number and length of vessels in samples treated with extract was showed a significant decrease compared to the control (P <0.001). The mean number and length of vessels in samples treated with Glycyrrhizic acid was showed a significant reduction compared to the control (P <0.05). Compare this parameters, in samples treated with Licorice extract to samples treated with Glycyrrhizic acid was showed a significant decrease (P <0.05). Both of, licorice extract and Glycyrrhizic acid have inhibitory effect on angiogenesis in Chick chorioallantoic membrane, however, The inhibitory effect of extract is stronger than Glycyrrhizic acid. Therefore licorice and Glycyrrhizic acid can be as suitable condidate on angiogenesis study.

In modern societies acceptability of treatment with complementary medicine has increased overtime. The purpose of this study was to determine the use of alternative and complementary medicine and its related factorsin residents of the Khorramabad city. This cross-sectional study was carried out using multi stage sampling method on 790 person over 15-year-old clients referring to a number of health and treatment centers and hospitals in Khorramabad town in 1393 (2014 A.D). Data collection, was self-made questionnaire to be confirmed of the validity and reliability. The information of questionnaire included demographic data on individual characteristic, using different kinds of complementary medicine until then and in the recent year and the level of satisfaction of these methods. Chi-square testwas used to data Analysis. In this study 790 subjects were surveyed using the questionnaire. The mean age of the study participants was 38.9±9.8 years.79.8% of the subjects had used at least one of the methods of complementary medicine. Among the participants, 58.2 %had used at least one of the complementary medicine in the previous year. Herbal medicine and prayers treatment had the highest use with 69.2% and 37.2%, respectively. The least used methods were chiropractics (0.8%), homeopathy (0.9%), and hypnotism (1.4%). Obesity (15.8%), migraine (14%) and arthritis (10.8%) were the most prevalent problems for which the participants resorted to complementary medicine. Given the high prevalence use of variety of complementary medicine methods, ensurethe effectiveness of these methods especially Herbal medicine for preventing and treating diseasesis Necessary.

patients undergoing hemodialysis repetitively experience pain and anxiety related toarterivenous fistula (AVF) punctures. Using of appropriate methods of pain relief in this patients is very important. The purpose of this study was to compare the effect of lidocaine gel and inhalation of lavender aromatherapy on pain intensity of arterivenous fistula puncture in heamodialysis patients. In this before and after clinical trial study, 40 heamodialysis patients were selectedthrough using of convenience sampling method.Pain intensity measured after needle insertion in AVF in three stages including without any intervention, after applyinglidocaine2% gel, and using of lavender aromatherapy in the three consecutive heamodialysis sessions of each stage. Visual analogue scalewas used to evaluate and determine pain intensity by patients immediately after cannulation. Data were analyzed using the SPSS version 16.0software and Repeated ANOVA test. Showed that the mean pain score in three stages of without any intervention, using lidocaine gel and inhalation of lavender aromatherapy were 5.54±1.94, 3.81±1.46 and 3.34±2 respectively. There was significant difference between the mean pain score in before and after using lidocaine gel (p˂0.001). There also was significant difference between pain score in before and after and inhalation of lavender aromatherapy (p˂0.001). However there was not any significant difference between pain score using lidocaine gel and inhalation of lavender aromatherapy (p꞊0.236). Venipuncture for AVF cannulation causes moderate pain in hemodialysis patients. Inhalation of lavender aromatherapy is as effective as lidocaine2% gel to decrease thispain in hemodialysis patients. Therefore, it recommends that nurses use this complementary pain relief method instead of pharmaceutical method.

The perineal pain resulting from episiotomy is a stressful factor in primiparous women which interferes with their ability of nursing and doing their duties as a mother. Cold therapy is a topical treatment which is effective in relieving inflammation and wound healing. Olive oil also increase the rate of wound healing. The present study has been conducted to evaluate and compare the effect cooling gel pads and topical olive oil on the intensity of episiotomy pain and wound healing in primiparous women referring to hospitals affiliated with the Gilan University of Medical Sciences in 2014. This randomized clinical trial was conducted on 90 primiparous women who referred to hospitals affiliated with the Gilan University of Medical Sciences. The participants were randomly allocated to two groups: those receiving cooling gel pads (for 20 minutes 12 hours after labor and in case necessary, for 10 days) and the topical olive oil (2 times a day, 12 hours after delivery and for 10 days). The two groups were evaluated interms of episiotomy pain intensity through visual analogue scale (VAS) and analgesics usage for 3 times: the 12 hours, 5th and 10th day after episiotomy. The two groups did not show any significant differences in demographic features and other intervening variables. There was a statistically significant difference in the intensity of perineal pain in two groups at 12 hours (p=0.04) and on the day 5 after episiotomy (p= 0.03). Using olive oil can reduce the pain of episiotomy be recommended in primiparous women. Futher studies are required to elucidate the antinociceptive effects of olive oil.

Infants perceive pain more than children and adults. Vaccination is one of the most common painful procedures in infants, so various methods have been proposed to assess the pain related vaccination and decrease the pain. The main object of this study is to compare the effects of seed therapy and breastfeeding on pain related vaccination in infants. Methods and materials: In a randomized clinical trial, 96 infants 6-12 months who were referred to health care center for HB, and DTP or MMR vaccination were allocated randomly. After parents consents they were assigned to one of the breastfeeding, seed therapy and control groups.Their pain were assessed by neonatal infant pain scale (NIPS) immediately after injection. Data were analyzed by descriptive analytic methods (T). The results showed that the means of pain score were significantly different between three groups (P<0/001). Post hoc LSD test showed that the differences between the breastfeeding and control groups (P<0/001), breastfeeding and seed therapy groups (P=0/002) and also control and seed therapy groups (P = 0/02) were statistically significant. Results showed that both methods of seed therapy and breastfeeding were effective for decreasing pain related vaccination in infants 6 and 12 months. In addition the effect of breastfeeding was significantly more than seed therapy.

As regards, about 80% of all latex allergy caused by latex gloves and the use of steroidsto treat this allergyis associated with local and systemic complications, therefore the research be necessary for treatment with fewer side effects. This study examined the impact of Alcea Althea on latex allergy in operating room personnel in hospitals of Arak city. This study was a double-blind clinical trial. Among operating staffs with allergies, samples were selected by simple random sampling. Then randomly divided into two: (intervention=33, control=33) groups. The intervention consisted of 5 mL topical solution from8%ofaqueous extract of Alcea Althea before and after the use of latex gloves for 30 days. Before and after intervention, samples were examined by a dermatologist. Samples completed self-assessment questionnaire of “Symptom Severity of Natural latex allergy”. The data were analyzed by SPSS 20 using Chi-square, Independent t-test, paired t-test and Analysis of Covariance. In this study, the mean age of staff was 32.45±6.69 in group control and 29.68±7.15 in intervention group. There was no significant different between groups in term of demographic. Results of this study showed that before intervention, severity of latex allergy symptoms between two groups didnt have any significant difference (P = 0.34), but after the intervention was seen significant difference (P= 0.013). Also before and after the intervention in control group, was not significantly difference in scores of symptoms severity of natural latex allergy (P= 0.11), however, for the control group was significantly difference (P= 0.008). According to Aqueous Extract of Alcea Althea reduce the symptoms of latex allergy, thus can be used as an effective herbal supplement helping to reduce the side effects of latex allergy.

Herbs are used in many domains, including medicine, nutrition, and flavonoides. Matricaria chamomilla have been recognized to have pharmaceutical properties, e.g. antioxidant, anti-inflammatory, antimicrobial, and anticarcinogenic effects. It has Polyphenols compounds with antioxidant activity. The purpose of this study was antioxidant properties of various extract (ethanolic, metanoli and hydroalcholic) and parts (stems & leavs and flower) of Matricaria chamomilla. Three extracts (ethanolic, metanoli and hydroalcholic in 1, 2, 5 and 10 PPM cocentration) were prepared. Then antioxidant activity of various extract (ethanolic, metanoli and hydroalcholic) and parts (stems & leavs and flower) of Matricaria chamomilla was measured by two DPPH and FRAP assays. The hydroalcholic extracts (10PPM concentration) of Matricaria chamomilla flower in FRAP and DPPH assay have highest antioxidant power. All extracts showed antioxidant activity in both methods but the results showed that hydroalcholic extract has better activity in antioxidant assays. Also, it can use for treatment many diseases.