Jentashapir Journal of Cellular and Molecular Biology
Volume:5 Issue: 6, Dec 2014

Pleomorphic adenoma (mixed tumor) is the most common neoplasm of the salivary gland. It is usually a benign, slow-growing and well-circumscribed tumor. However, there are rare reports of a subset of these tumors metastasizing to distant sites without undergoing malignant transformation. Here we describe a case of pleomorphic adenoma of the parotid gland that metastasied to the cervical lymph node coincidentally with similar appearance of the primary lesion in the ipsilateral parotid gland.. A 78-year-old male with right sided cervical lymph node and ipsilateral parotid mass from one year ago came to Imam Khomeini hospital. Physical examination, a painless firm mass was found within year, the parotid and lymph node of the neck concomitantly with no other organs abnormalities. A diagnosis of pleomorphic adenoma was made from completion parotidectomy and cervical lymphadenectomy. No histologic characteristic of malignancy were seen in either specimen; therefore a diagnosis of benign metastasizing mixed tumor was rendered.. Benign metastasizing pleomorphic adenoma is a rare and controversial but distinct clinical entity. Although the definition of the term benign precludes metastatic disease, these tumors do not demonstrate any malignant features yet metastasized to distinct sites. It remains to be determined whether this benign metastasizing pleomorphic adenoma is really low grade salivary malignancy..

Fat, oil and grease (FOG) in municipal wastewater treatment plant (MWWTP) caused many problems.. This study aimed to determine the removal efficiency of FOG in Shiraz MWWTP.. The removal efficiencies of FOG in the MWWTP were studied from June 2011 to September 2011 in Shiraz (Iran). The influent and effluent wastewater samples were collected in a volume of one liter (4 samples per week) and analyzed according to the standard methods. Samples are transferred to the laboratory immediately. The concentration of FOG was determined using the solvent extraction and separating funnel and then compared with the effluent standards. To analyze the data, SPSS (version 11.5), Chi-square test and t test were used.. The results showed that the FOG amount in input raw sewage in the MWWTP from June 2011 to September 2011 was around 25.5 mg/L and the amount in treated wastewater was about 8.1 mg/L. The FOG removal efficiency in this refinery was about 70% and met the environmental standards for the discharge (less than 10 mg/L) (P < 0.05).. The effluent can be discharged to surface waters or used for irrigation. In order to the FOG concentration met the effluent standards, it is very crucial to control the entrance of industrial wastewater to the municipal wastewater collection networks. Otherwise, the MWWTP should be upgraded and the special techniques used to reduce FOG..

The species of the genus Malassezia are lipophilic and dimorphic yeasts that are regarded as part of the normal flora of the skin of humans and warm-blooded animals. These organisms are the cause of superficial mycosis in humans and other animals, and are common in pityriasis versicolor and seborrheic dermatitis.. The purpose of this study was to determine the frequency of common Malassezia species in patients affected by pityriasis versicolor and seborrheic dermatitis using of the nested PCR method, in the city of Ahvaz..Patients and In the present study, 85 samples from patients with pityriasis versicolor and seborrheic dermatitis were analyzed by the nested-PCR method. During the first stage, the internal transcribed spacer (ITS) region from the ribosomal DNA was reproduced using primers ITS4-R and ITS1F-N. During the second stage, the product of the first step was used as DNA and using three special primer pairs, including Mf-F, 5.8SR and M.gl-F, 5.8SR and M.rt-F and M.rt-R, the inner part of the first phase was detected.. The most common isolate was Malassezia furfur (51.3%) followed by M. globosa (35.2%) and M. restricta (13.5%). Amongst the 30 patients with seborrheic dermatitis, in 15 cases (65.2%) M. restricta, in six cases (26.1%) M. globosa and in two cases (8.7%) M. furfur was detected and in seven patients no isolate was detected.. The nested-PCR is a rapid and repeatable method for identification of important Malassezia species and this method is recommended for use on more patients. In addition the most common agents of pityriasis versicolor and seborrheic dermatitis were M. furfur and M. restricta, respectively..

The current studies showed that obesity could lead to hyperhomocysteinemia as well as migraine.. Thus, this study aimed to assess the association between abdominal obesity and serum levels of homocysteine in migraine patients..Patients and This cross-sectional study was conducted on 120 migraine patients, aged 15-67 years, who were referred to Isfahan Korshid and Imam Mosua Sader clinics in 2013. Abdominal obesity indicators such as waist circumference (WC), hip circumstance (HC), waist-hip ratio (WHR) and waist-height ratio (WHtR) as well as fasting homocysteine concentration were measured for all patients. Data was analyzed by the SPSS 19 software using t-test, χ2 and regression.. In this study, 7.7% of men and 18.8% of women had hyperhomocysteinemia. Abdominal obesity was prevalent in 3.8% of men and 27.1% of women. In the entire population, homocysteine concentration was positively associated with WC (P ≤ 0.001), WHR (P ≤ 0.001) and WHtR (P ≤ 0.001), either in crude or adjusted models. In addition, such relationship was seen in women. Amongst men, a significant association was found between WC and homocysteine levels (P = 0.03), yet the association between WHR (P = 0.06), WHtR (P = 0.08) and homocysteine concentration was marginally significant.. Waist circumference, WHR and WHtR were positively associated with homocysteine concentration in migraine patients. However, further studies particularly of prospective nature are required to confirm our findings..

Sphenoid sinus is surrounded by many vital vascular and nervous structures. In more than 20% of patients with chronic sinusitis, involvement of sphenoid sinus has been observed. Besides, sphenoid sinus is an appropriate route to access anterior and middle cranial fossa in surgery. Therefore, it is important to have an adequate knowledge about the contents of sphenoid sinus and its proximity for nasal endoscopy, sinus surgeries and neurosurgeries.. The aim of this study was to study sphenoid sinus proximity with carotid artery and the optic nerve using computerized tomographic imaging.. In this prospective study, computerized tomographic images of sphenoid sinus of patients referred to Imam Khomeini and Apadana hospitals were studied. The images were studied regarding any bulging, as well as not having a bone covering in sphenoid sinus regarding internal carotid artery and optic nerve. Furthermore, unilateralness or bilateralness of their relationships was studied.. Among 468 coronal and axial CT scan images of sphenoid sinus, 365 (78%) showed post-sellar pneumatization and 103 (22%) pre-sellar pneumatization. Regarding existence of internal septa, 346 (74%) cases showed multiple septation, and the remaining images were reported to have a single septum. According to the reports of CT scan images, the existence of bulging as a result of internal carotid artery and uncovered artery were 4.22% and 5.8% in the right sinus, 4.9% and 5.4% in the left sinus, and 4.34% and 4.6% in both sinuses, respectively. According to the reports of CT scan images, existence of bulging as a result of optic nerve and uncovered nerve were 5.7% and 4.3% in the right sinus, 6% and 5.4% in the left sinus, and 12% and 3.2% in both sinuses, respectively.. Due to variability of sphenoid sinus pneumatization and the separator blade of the two sinus cavities, careful attention is required during sinus surgery to avoid damage to neural and vascular structures in its proximity.

Myofascial trigger point is one of the most common causes of musculoskeletal disorders. Myofascial trigger point in upper trapezius has been reported as a symptom in patients with neck and upper thoracic pain.. The purpose of this study was to investigate the effect of dry needling compared with ischemic pressure on trigger point in upper trapezius muscle.. 28 subjects with myofascial trigger point in upper trapezius participated in this study. The subjects were randomly assigned to two groups: dry needling (n = 13) and ischemic pressure (n = 15). The neck lateral flexion range of motion was measured before and after treatment in both groups using a standard goniometer. Paired t-test was used to determine any significant difference in range of motion after treatment sessions compared with pre-treatment score in control and experimental group. Analysis of Covariance (ANCOVA) was calculated to determine the significance of differences between the control and experimental groups in post-test scores, with pre-treatment scores used as covariates in the analysis.. Statistical analysis (paired t-test) revealed significant increase in neck lateral flexion range of motion in contra-lateral side after treatment sessions in control and experimental group compared with pre-treatment score (P < 0.05). However, only dry needling was effective in increase of range of motion in Ipsi-lateral side (P = 0.001). In the ANCOVA, controlling for pre-test scores, no significant difference was found between the two groups in the after treatment sessions (P = 0.06) and (P = 0.15).. The application of DN produces an improvement in ILF and CLF can be prescribed for subjects with MTP in UT muscles..

Premenstrual syndrome (PMS) is a group of disorders that many girls and women suffer from. It is well known that an appropriate diet as well as environmental factors plays a major role in quality of life.. This study evaluates food patterns for university student girls who suffer from PMS and are healthy.. Eighty-six university student girls from Ahvaz Jundishapur University of Medical Sciences participated in the survey and PMS was diagnosed using the diagnostic criteria of the American College of Obstetricians and Gynecologists. They completed a daily symptom-rating questionnaire for PMS symptoms. The score of categorical symptoms (mood-emotional and gastrointestinal disorders, pain, fatigue-focus, and other disorders) were determined separately. Student food pattern was determined according to the Iranian food pyramid. The correlation between symptom scores and food group servings was determined by the Pearson correlation coefficient.. The score for each categorical symptom showed significant differences between healthy and students who suffered from PMS (P < 0.001). A significant negative relationship was observed between milk consumption and pain score (P = 0.038, r = -0.224), and between total dairy consumption and pain score (P = 0.019, r = -0.253). Total disorder scores showed a significant negative relationship with total dairy product (P = 0.024, r = -0.243).. The results of the survey indicate that PMS symptoms are related to consuming less milk or dairy products. Therefore, an appropriate intake of foods according to standard food patterns (like the Iranian food pyramid) is recommended.

Lung biopsy is the gold standard for definitive diagnosis of interstitial lung diseases (ILD). A biopsy is usually performed by non-anatomical wedge resection as an open or thoracoscopy approach.. We aimed to compare minithoracotomy approach with thoracoscopy in ILD..Patients and Overall, 43 patients with ILD who had referred to Imam Khomeini Hospital for open lung biopsy from 2008 to 2013, were enrolled, and their clinical findings, chest radiography, high resolution computed tomography (HRCT) and spirometry were considered before referral.. A total of 43 (12 males and 31 females, with mean age of 41.90 ± 8.64 years) patients underwent minithoracotomy for open lung biopsy. Minithoracotomy mortality rate was 0% compared to the 0 - 5.2% reported for thoracoscopy. The mean hospital stay for minithoracotomy was 2.3 ± 0.97 days compared to 4.9 ± 1.53 days reported for thoracoscopy (P < 0.05). The complication rate was 0.05% and mean length of operation time was 35 minutes.. Minithoracotomy had fewer complications, shorter length of operation and no operative mortality compared to thoracoscopy. Minithoracotomy may be the method of choice even in patients with severe shortness of breath..

Pregnant women should be under evaluation through screening tests during 11 - 14 weeks of pregnancy. Increased awareness level of physicians is of great importance in referring pregnant women for screening in the first trimester of pregnancy. In addition, patients’ awareness is of great importance for early discovery of chromosomal abnormalities and fetal mental retardation. Verification of these anomalies using more diagnostic tests can lead to early awareness and prohibition from the birth of malformed infants.. The aim of this study was to examine the extent of awareness of physicians and patients from the first trimester screening tests..Patients and In this descriptive cross-sectional study, 100 physicians (65 general physicians and 37 gynecologists) as well as 385 females, 18 - 45 years old, referred to the Women''s Clinic of Ahvaz Imam Khomeini Hospital participated. Two separate questionnaires containing two demographic and profile sections and questions related to general knowledge were used in this study. The data collected were analyzed using descriptive statistics (frequency distribution, average, standard deviation) and SPSS version 18.. The average age of patients was 29 (18 - 45 years) and 38 ± 6 (24 - 52). A total of 81 patients (21%) were illiterate, 217 (56.4%) had diploma or below, and 87 (22.6%) had higher education; 234 and 151 participants were respectively employed and unemployed. In a comparison of patients’ awareness of the first trimester screening tests, 70.4%, 17.4% and 12.2% had poor, average and good scores, respectively. In addition, in a survey on physicians, 24%, 46%, and 30% achieved poor, average and good scores, respectively. A significant relationship existed between the patients'' awareness and their job and education (P = 0.01); in the physicians’ group, gynecologists had higher awareness due to the existing rules.. The results showed that awareness of patients and a few doctors about the first trimester screening tests was respectively weak and middle level, showing that there is an urgent need for greater awareness in this field, regarding the importance of detecting some chromosomal abnormalities prior to birth..