Journal of Inflammatory Diseases
Volume:19 Issue: 5, 2016

There are reports that essential oils of different species of eucalyptus have special properties including anti-bacterial, antiviral, anticancer and insecticidal activities. Most of plant essential oils are dissolved in polar or non-polar solvents before examination. The aim of this study was to determine the cytotoxic effects of different solvents and essential oil of eucalyptus on human fibroblast cells. This experimental study was performed in the Institute of Biotechnology affiliated to Iranian Research Organization for Science and Technology during 2013-2014. The studied solvents were including ethanol, propylene glycol, dichloromethane, and dimethyl sulfoxide. Fibroblast cells were seeded in 96-well plates. After 24 h incubation at 37ºC, the cells were treated with different concentrations of the solvents or essential oil of eucalyptus (0.05-1 mg/ml). The viability of the cells was determined by the colorimetric MTT assay. Data were analyzed using T-test and One-way ANOVA. The lowest cytotoxic effect against fibroblast cells was related to 1% ethanol and propylene glycol, while the highest cytotoxic effect was related to 10% dimethyl sulfoxide that decreased cell survival by 47%. Essential oil of eucalyptus also induced fibroblast cell death at concentrations higher than 0.05 mg/ml. For clinical application of essential oil of eucalyptus, using solvent with appropriate concentration is necessary to prevent its cytotoxic effects.

Investigating effects of stress in animal models may suggest clinical treatments or prevention protocols for effects of stress in humans. The aim of this study was to determine the histological effects of chronic multiple stress on rat ovary. This experimental study was conducted in 18 adult female Wistar rats that were randomly divided into two equal groups in Qazvin University of Medical Sciences during 2014. The mice were exposed to different stress including food deprivation, water deprivation, immobility at 4 º c, forced swimming, and isolation for 10 days in the under stress group while the mice in the control group were kept in their cages without any intervention. After the intervention period, the mice were anesthesized, the ovary of the animals were removed and weighed, and the ovary samples were prepared for light microscopic study. The number and diameter of corpus luteum, and the number of antral and preantral follicles were determined using Image Tool software. Data were analyzed using T-test. The mean number and diameter of corpus luteum significantly reduced in the under stress group compared to the control group. The mean number of antral and preantral follicles significantly reduced in the under stress group compared to the control group. With regards to the results, it seems that chronic multiple stress can have negative effects on rat ovary by reducing the diameter and number of corpus luteum and the number of antral and preantral follicles.

Apelin and omentin are adipose tissue-secreted hormones and affect the metabolism.

The aim of this study was to investigate the effects of long-term aerobic activity with different intensities on plasma levels of apelin and omentin in female rats.

This experimental study was conducted on 60 Sprague-Dawley female rats (2 -month-old) in laboratory affiliated to Shiraz University of Medical Sciences during 2014. Blood samples were taken from15 rats in the pre-test group to measure the variables of interest. The remaining rats were divided into three groups based on treadmill speed (12, 14, and 16m/min). After a single 45-min session of treadmill running, blood samples were taken. Data were analyzed using two-way ANOVA.

The plasma levels of apelin and omentin were not significantly different between the three post-test groups. But the difference between the pre-test group and the post-test groups was statistically significant.

With regards to the results, adipokines response (apelin and omentin) to a single-session exercise is not the same and the secretion of each one occurs at a specific intensity and duration threshold of sports activity.

Studies have shown that melatonin consumption can decrease weight and body fat mass percentage. The aim of this study was to determine the effects of melatonin supplementation on weight and body fat mass percentage in overweight or obese people. This clinical trial was carried out on 38 overweight or class-I obese adults (8 men and 30 women) in Tehran in 2013. Subjects were allocated to melatonin or placebo groups. The intervention period was 12 weeks and 3 mg/day melatonin was administered. Data were analyzed using repeated measure ANOVA and paired T-test. Weight and body mass index was significantly decreased in both groups in the study period, but these changes were only significant in the first six weeks of the study. Body fat mass percentage was significantly decreased in the melatonin group. Salivary melatonin level was not significantly different in both groups after the study period. With regards to the results, it seems that supplementation with 3 mg/day melatonin does not make a significant decrease in weight and body mass index, but decrease body fat mass percentage. More investigations are required to confirm the findings.

Due to the short half-life of parathyroid hormone (PTH), intra-operative quick PTH measurement (immediately after removal of adenoma) is beneficial to identify and evaluate the adequacy of tissue removal and to reduce reoperation and more extensive surgery.

The aim of this study was to compare pre-and postoperative parathyroid hormone levels with frozen section during parathyroidectomy.

This analytical study was conducted on 25 patients with primary hyperparathyroidism referred to Velayat Hospital in Qazvin for parathyroidectomy during 2013. Serum PTH levels were measured before surgery and 10 minutes after surgical removal of adenomas and the results were compared with the results of frozen section during surgery. Data were analyzed using paired T-test.

Mean PTH level was 222±68.5 before surgery and was 56±57.7 after removal of the adenomas. The difference was statistically significant. These results were consistent with the results of frozen section.

With regards to the results, it seems that frozen section technique is an appropriate method to assess the surgery and to reduce the extent of surgery.

Insufficient sleep or poor sleep quality affect learning, memory and performance and cause behavioral disorders. Watching television (TV), using computer and internet, playing computer games, and caffeine intake are of factors affecting sleep quality. The aim of this study was to determine the association of sleep quality with watching TV, computer games and caffeine intake in adolescents of Minoodar district, Qazvin. This cross sectional study was conducted in 319 adolescents (10 to 18 years old) that were selected by multistage cluster random sampling method during 2010-2011. Demographic data and data on duration of playing computer games and watching TV were collected. Food frequency questionnaire and BEARS questionnaire were completed. Data were analyzed using Chi-square test, logistic regression analysis and ANOVA. Mean age was15±2.43 years. Of 319 adolescents, 162 (50.8%) were female. The duration of watching TV or video was not significantly different between boys and girls. The duration of playing computer or video games was statistically different between boys and girls. There was no correlation between sleep quality and duration of watching TV or videos in a day, duration of playing computer or video games in a day, and caffeine intake in adolescents. With regards to the results, it seems that there is no association between sleep quality and watching TV, playing computer games and caffeine intake.

Smile is one of the most important factors determining the attractiveness of a person and has an important role in his mood and influence on others. The aim of this study was to evaluate the smile satisfaction and its related indicators in the students of School of Dentistry affiliated to Qazvin University of Medical Sciences. This cross sectional study was conducted on 80 students of School of Dentistry in Qazvin during 2013-2014. Digital photograph was provided from students’ smile. Smile esthetics of pictures was evaluated by three faculty members of restorative and orthodontics departments based on visual analogue scale. Smile satisfaction was evaluated by the students. Smile line ratio, buccal corridor ratio and symmetric ratio were measured by Photo shop CS5 software. Data were analyzed using Pearson’s correlation coefficient. Mean smile esthetics score was 59 ± 10.5 and 71 ± 9.4 in male and female students, respectively and the difference was statistically significant. Mean self-reported smile satisfaction was 73.7 ± 7.8% and 72.4 ± 17.9% in male and female students, respectively and the difference was not statistically significant. Smile line ratio was significantly different between male and female students, but the differences in buccal corridor ratio and symmetric ratio was not statistically significant. There was positive significant correlation between smile line ratio and smile esthetics score. Among the morphometric indices, only smile line ratio had significant correlation with smile satisfaction in male students. The correlation between smile line ratio and smile satisfaction indicates the high capability of this morphometric index for evaluating smile satisfaction.

Identifying the psychological factors involved in psychological problems of patients with cancer is very important. The aim of this study was to determine the role of alexithymia in predicting psychological symptoms in patients with cancer. This cross sectional study was conducted in 102 patients with cancer selected by convenience sampling method in Ardabil during 2014. The measurement tools were the Persian version of Toronto Alexithymia Scale (TAS-20) and the Hopkins Symptom Checklist-25 (SCL-25). Data were analyzed using Pearson's correlation coefficient and regression analysis. There was significantly positive correlation between alexithymia and all psychological symptoms. In regression analysis, alexithymia was predictor of all psychological symptoms. With regards to the results, it seems that alexithymia is able to predict psychological symptoms. Therefore, paying more attention to psychological determinants in patients with cancer and providing appropriate treatment strategies can be effective to alleviate the mental suffering.

Pulsatile tinnitus is the result of blood flow related sounds transmitted to the inner ear and coincides with heartbeat. Although pulsatile tinnitus is a rare entity, this symptom is most often indicative of a serious underlying disease in central nervous system. Unfortunately, this symptom is often not properly assessed by clinician that leads to delayed diagnosis of underlying brain pathology. In this report, a patient is presented with chief complaint of tinnitus that had many medical visits for 2 years. Finally, a cerebral vascular malformation was diagnosed with regards to physical examination and neuroimaging findings.

The aim of this analytical study was to investigate the association of social security feeling and Demographic factors in women heading households of Qazvin in 2014. The study subjects were 310 women heads of households selected by random sampling method. Data were collected through a standardized questionnaire for social security feeling. Mean communication security score was 2.13. Mean emotional, physical, and financial security scores were 2.71, 2.54, and 2.27, respectively. Mean social security score was 2.41 in women heading households. The association of heads’ income, family size, and heads’ education level with social security feeling was statistically significant. It seems that providing free consultation is effective to increase communication security in women heading households and providing job opportunities appropriate for their financial needs is effective to promote social security feeling.