Relation of Total Antioxidant Capacity with Static Volumes as Lung Function in Adult Males with Chronic Asthma

Recent evidence has shown that the asthma patients have lower antioxidant capacity (TAC) than healthy individuals. However, little information on the influence of TAC on lung function is available in these patients. This study aimed to determine relation of TAC with Spirometric markers in these patients.
For this purpose, thirty sedentary adult males with mild to moderate asthma aged 40 ± 7 years were enrolled to study by targeted sampling. Fasting blood samples were collected with regard to measuring TAC of all patients. Anthropometric and spirometry markers (FVC, FEV1, FEV1/FVC) were also measured in all patients. Data from TAC and other variables were analyzed by Pearson correlation.
Data showed that TAC was positively correlated with FVC (P=0.036, r=0.48), FEV1 (P=0.002, r=0.73) and FEV1/FVc (P=0.001, r=0.77) in studied patients.
Based on these data, it is concluded that TAC is a suitable marker for predict lung function and disease intensity in males with asthma.