The Relationship between Fasting and Postprandial Blood Glucose with HbA1C in Type 2 Diabetes.

HbA1C measurement is a gold standard for controlling blood glucose in diabetic patients. There is little information about fasting and postprandial blood glucose effect on HbA1C. The aim of the present study was to investigate the relationship between fasting and postprandial blood glucose and some other factors with HbA1C on type 2 diabetic patient in Kermanshah Diabetes Research Center. 173 type 2 diabetic patients were selected in a sectional-analytic study by easy sampling. Information were completed using a questionnaire and blood glucose were measured before and 2 hours post-breakfast and at 4pm every 2-4 weeks for a period of 3 months. At the end of the third month HbA1C were also measured. Based on HbA1C, patients were divided into three groups. Data were analyzed by SPSS software. There was a relationship between fasting, 2 hours post-breakfast and 4pm blood glucose and HbA1C. Correlation coefficient was r = 0.49 (p<0.0001) for fasting blood glucose, (r=0.754, p<0.0001) for 2 hours post-breakfast and (r=0.811,p<0.001) for 4pm blood glucose. Also there were a relationship between duration of the disease (r=0.363,p<0.0001) and type of treatment(r=0.338,p<0.0001) with HbA1C. There was no relationship between age, sex, BMI, family history of diabetes and education with HbA1C. The results of this study showed that there was a relationship between fasting and 2 hours post-breakfast and 4pm blood glucose with HbA1C but, the most relationship was found between 4pm blood glucose with HbA1C. Therefore, fasting blood glucose is not a good character for diabetes control and postprandial blood glucose measurement should be carried out for better control of diabetes.