Comparing the Effects of Adding Pancoronium and Fentanyl to Lidocaine During Intravenous Regional Anesthesia

Many patients because of ischemic heart diseases, cerbral or pulmonary diseases are not appropriate candidates for general anesthesia in upper limb surgeries. Intravenous regional anesthesia (IVRA) is one of the anesthetic procedures for these patients. The aim of this study was to compare the effects of adding Pancronium and Fentanly to Lidocaine during IVRA.

In a single-blind clinical trial investigation, 46 patients-who were candidated for hand surgeries-were studied. The subjects were randomly classified into two groups. The first group who used 38 cc Lidocaine 0.5% and 2 cc sterile water (control group) and the second group who used 38 cc Lidocaine 0.5% besides 50 mgr Fentanyl and 0.5 mgr Pancronium (trial group) for sensory and motor blacking. Data analysis was performed by t-test through SPPS 10 software.

The average time for storing of sensory and motor block in trial group was significantly faster than control group. Additionaly, the average time for starting of sensory and motor block in control group was significantly lower than trial group.

This study revealed that adding of Fentanyl and Pancronium causes better motor and sensory block and provide better relaxation for muscles during surgery.