Comparative Study of Emdogain and Connective Tissue Graft (CTG) in Treatment of gingival recession

The aim of this study was to clinically evaluate the use of Enamel matrix protein derivative(EMD) combined with the coronally positioned flap (CPF) to treat gingival recession compared to the subepithelial connective tissue graft (CTG). In this clinical trial study, thirteen patients each with two or more similar bilateral Miller clI or II) gingival recession(40 recessions) were randomly assigned to the test (EMD+CPF) or control group(CTG). Recession depth(RD), Recession width(RW), probing depth(PD), keratinized gingiva(KG), plaque index(PLI) were recorded at baseline and at 1,3,6 months after treatment. Results were analyzed by Kolmogrov-Smirnov, Wilcoxon,Friedman, Paired-samples T Test. The average percentages of root coverage for control and test groups were 63.3% and 55% respectively. Both groups showed significant (KG) increase (p<0.05). RD decreased significantly in both groups. The results of Friedman test were significant for clinical indices (p<0.05), except for PD in conrol group (p=0.166). EMD showed the same results as CTG with relatively easy procedure to perform and low patient morbidity.