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فهرست مطالب نویسنده:

j. malekzadeh

  • E. Masnavi, S. Hassanzadeh*, K. Karimi, J. Malekzadeh, S.S. Khoramrooz
    Aims

    Every year around the world, hospital infections and resistance to antibiotics lead to many complications in hospitalized patients. This study aimed to determine and compare the antibacterial effect of hydroalcoholic extract of Rosa canina plant (Rosa canina L) on Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus bacteria isolated from surgical wounds in Yasuj hospitals.

    Materials & Methods

    In this cross-sectional study, the effect of Rosa canina L hydroalcoholic extract on 20 samples of Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus was investigated. The Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and zone of inhibition (ZOI) of each clinical sample were investigated and compared with the standard sample. The results were statistically analyzed by SPSS 16 software.

    Findings

    Rosa canina L hydroalcoholic extract had no antibacterial effect on Pseudomonas aeruginosa. The lowest inhibitory concentration was related to Staphylococcus aureus 125 µg/ml, Escherichia coli 325 µg/ml and Klebsiella pneumoniae 350 µg/ml, respectively. The difference in minimum MIC, MBC and ZOI between clinical and standard samples was not statistically significant. The ZOI diameter of Klebsiella pneumoniae and Escherichia coli clinical samples were equal (9.8 mm).

    Conclusion

    The hydroalcoholic extract of Rosa canina L has a better antimicrobial effect on Staphylococcus aureus than the other 3 investigated bacteria and has no effect on Pseudomonas aeruginosa. There is no difference between the effect of the examined extract on clinical and standard samples, and the effect of this extract on different bacteria is different.

    Keywords: Plant Extracts, Rosa, Anti-Bacterial Agents, Bacteria
  • N. Hashemi Mohammad-Abad, L. Hoseiniyan, J. Malekzadeh*
    Aims

    Depression is a common mental disorder. This study aimed to evaluate the relationship between serum lipid profiles and serum serotonin with depressive disorder.

    Materials & Methods

    This study was carried out on patients with depressive disorders referred to Shahid Mofteh Clinic in Yasuj, Iran, in 2016. The total serum cholesterol, LDL-C, HDL-C, and serum serotonin of 45 patients with the depressive disorder as a case group and 45 normal people without depressive disorder as a control group was measured. Age, sex, weight, and height were matched in both groups. Diagnosis of depression was conducted using both the Beck and Hamilton depression rating scale, followed by an interview by a psychiatrist. Data were analyzed using the SPSS 19 software by sample t-test and the chi-square test.

    Findings

    The LDL-C serum concentrations of the case group was higher than the control group (121.1±30.9 vs107.9±36.9; p=0.07); moreover, the HDL-C serum of the case group was significantly lower than the control group (52.6±11.9 vs. 34.4±9; p<0.0001). The Serum serotonin of the case group was higher than the control group, but this difference was not statistically significant (455.9±393 vs. 418.1±224.4; p=0.58). The total cholesterol and Triglyceride of the case group were higher than the control group, but these differences were not statistically significant (178±37.8 vs. 191.2±47 and 127.4±56.2 vs. 148.5±88.4 respectively; p=0.14).

    Conclusion

    The serum HDL-C concentration of depressed patients is lower than normal people, and the serum LDL-C concentration of depressed patients is higher than normal people.

    Keywords: Depression, Cholesterol, Serotonin, LDL-C, HDL-C.
  • H. Sadeghi Mansoorkhani, M. Alamdari, S. Hasanzadeh*, S. Jokar, E. Panahi Kokhdan, J. Malekzadeh, R. Abassi
    Aims

    Constipation is an important problem and dysfunction of the digestive system. In the traditional beliefs of different parts of the world, especially Iran, Rosa damascene Mill. has several properties, including sedative, anti-inflammatory, anti-seizure, anti-depressant, and laxative effects. This study aimed to evaluate the effect of hydroalcoholic extract of Rosa damascene Mill. in treating chronic constipation in adults.

    Materials & Methods

    This randomized clinical trial was performed in 2018 in Shahid Mofteh Specialized Clinic of Yasouj on 160 patients with chronic constipation referred to internal medicine and gastroenterologists. Extracted hydroalcoholic extract of Rosa damascene Mill. and lactulose syrup was used; The control group received 20cc of lactulose syrup twice a day, and the intervention group received a hydroalcoholic extract of Rosa damascene Mill. two times a day in the form of 500mg capsules twice a day for one month. Data were analyzed using SPSS 19 software and T and chi-square tests with 95% confidence interval.

    Findings

    During the intervention process, 16 people did not refer to the necessary follow-up, and the necessary information was collected from 144 patients with chronic constipation. Sixty-eight patients (4.2%) were male, and 76 (52.8%) were female. The mean age of patients was 43.18±13.67, and the age range was 18 to 75 years. There was no statistically significant difference between the two groups' mean age and sex under Rosa damascene Mill.'s intervention. Hydroalcoholic extract and lactulose (p<0.05). Also, there was no statistically significant difference between the variables of frequency and ease of defecation between the two groups receiving lactulose and Rosa damascene Mill. hydroalcoholic extract before and after the intervention (p<0.05).

    Conclusion

    Hydroalcoholic extract of Rosa damascene Mill. has a similar effect to lactulose in the treatment of chronic constipation in adults.

    Keywords: Chronic Constipation, Hydroalcoholic Extract Of Rosa Damascene Mill, Lactulose
  • جواد ملک زاده، تکتم اعتضادی جمع*، سید رضامظلوم، علیرضا تسعیری
    پیش زمینه و هدف

    ارتباط ضعیف مابین مراقبین سلامتی از جمله عوامل خطری است که در برنامه پایش خطاهای دارویی و خطاهای مربوط به خطوط وریدی همیشه مدنظر سیستم های مراقبت سلامتی قرار می گیرد. یکی از مواقعی که ارتباط و انتقال اطلاعات نقش محوری در ارتقاء ایمنی بیمار بازی می کند هنگام تعویض نوبت کاری پرستاران است که انجام صحیح آن در قالب یک دستورالعمل استاندارد و مدون باعث ارتقاء عملکرد مراقبتی پرستاران در حوزه ایمنی و پیشگیری از وقوع خطاهای دارویی و مراقبت بهتر از خطوط وریدی توسط پرستاران می شود. این مطالعه با هدف تعیین تاثیر اجرای دستورالعمل مدون تحویل نوبت کاری پرستاری بر عملکرد ایمن پرستاران در حیطه مراقبت های مرتبط یا خطوط وریدی و دادن داروها در بخش های مراقبت ویژه انجام شد.

    مواد و روش ها

    این پژوهش یک طرح نیمه تجربی یک گروهی قبل و بعد با شرکت 56 پرستار شاغل در بخش های ویژه بیمارستان قائم(عج) بود که به روش آسان انتخاب شدند. میزان عملکرد مراقبتی پرستاران در حیطه مراقبت های مرتبط با دادن داروها در حوزه ایمنی قبل و بعد از اجرای دستورالعمل مدون نوبت کاری با سیاهه ارزیابی عملکرد مراقبتی پرستاران که روایی و پایایی آن با شاخص روایی محتوی و توافق مشاهده گران (95/0 = r) تایید شده بود، جمع آوری گردید.

    یافته ها

    مقایسه میانگین نمره کل عملکرد مراقبتی پرستاران در دو مرحله قبل و بعد از مداخله با آزمون تی زوج نشان داد بین دو گروه از نظر آماری تفاوت معنی داری وجود دارد(001/0> p). نتایج آزمون ویلکاکسون نشان داد که این تفاوت معنی دار در هر2 حیطه مراقبت های پرستاری مرتبط با دادن داروها و مراقبت از خطوط وریدی وجود داشت.

    بحث و نتیجه گیری

    تهیه، تدوین و اجرای یک روش قانونمند، جامع و کاربردی جهت انتقال اطلاعات مراقبتی بیمار در قالب یک دستورالعمل استاندارد تحویل نوبت کاری باعث کاهش بروز خطاهای دارویی می شود.

    کلید واژگان: تحویل نوبت کاری پرستاری، ایمنی بیمار در بخش های ویژه، عملکرد مراقبتی پرستاران، خطای دارویی
    J. Malekzadeh, T. Etezadi Jam, Sr Mazlom, Ar Taseiri
    Background and Aims

    Poor communication among health care providers includes risk factors that should always take into account in monitoring of medication errors and intravenous lines. Information exchange happens repeatedly among healthcare providers. An instance of such communication and exchange of information that plays a pivotal role in improving patient safety is during the nursing shift handovers. They should be done in a standard procedure، and they should be documented to improve the performance in the areas of safety and preventing medication errors and intravenous lines. This study was accomplished to investigate the effect of a standardized shift handover protocol on the safe performance of nurses in the areas of care of intravenous lines and medications.

    Materials and Methods

    This was a quasi-experimental، one group pretest/posttest study on 56 nurses working in intensive care unit in Qhaem Hospital who were conveniently selected. The safety performance level of nursing care were evaluated before and after implementation of written guideline using self-structured checklist of performance evaluation of nursing care. Validity and reliability of this instrument was determined by Content Validity Index and Inter Rater Reliability (r=0. 95).

    Results

    Study findings revealed that nurses’ mean score on the Safe Practice Evaluation Checklist increased significantly (p<0. 001). Wilcoxon test showed that there is a significant difference in the two areas related to the nursing care of medication and intravenous lines.

    Conclusion

    Development of a rule-based approach، comprehensive and practical standard protocol to transmit crucial and relevant information related to the patient care will improve safe performances of nurses in the area of medication and intravenous lines nursing care.

    Keywords: Shift Handover, Patient Safety, Nursing Care, Intensive Care Unit, Medication Errors
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