جستجوی مقالات مرتبط با کلیدواژه « cetrimide » در نشریات گروه « شیمی »

In this research, we develop and prepare some of the polymers based on polythioesters using cetrimide as an ionic liquid and phase transfer catalyst. All of the polymers were prepared through the reaction of 5,5'-methylenebis (1,3,4-oxadiazole-2-thiol) with five types of diacyl chloride derivatives in the presence of cetrimide as phase transfer catalyst in the mixture of water and chloroform at room temperature. The chemical structure of synthesized polymers was determined using 1H NMR and 13C NMR spectroscopy. The mechanical and thermal stability of the synthesized polymers were investigated. In addition, using DFT calculation, the chemical optimization of synthesized polymers was presented. Moreover, the catalytic activity of cetrimide was compared with four types of ionic liquid with phase transfer catalyst roles. Additionally, the application of synthesized polymers in bone cement was investigated.

This paper presents a comparative study between five ion selective electrode sensors which were constructed and validated to determine Cetrimide (CET) by direct potentiometry in pure drug and its mouthwash without sample pre-treatment. Precipitation based technique was used for sensors fabrication. The CET complexes with different types of polyvinylchloride matrix and different cationic exchangers, CET- carboxylated polyvinylchloride (sensor 1), CET- tetrakis (sensor 2), CET- phosphotungestate (sensor 3), CET-tetraphenylborate (sensor 4) and CET- carboxylated polyvinylchloride / tetrakis (sensor 5) were obtained in situ by soaking the PVC membranes in 1×10-4 M CET solution. Nitrophenyl octyl ether (NOPE) was used as plasticizer. Proposed sensors showed fast, stable Nernstian responses across a relatively wide CET concentration range of 7.81×10-6 M to 1×10-3 M (for sensor 1, 2 & 5) and 3.13×10-5 M to 1×10-3 M (for sensor 3 & 4) in the pH range of 1-10 (for sensors 1, 2 & 5) and 5-7 (for sensors 3 & 4). Suggested sensors were found to be stable for several weeks without any measurable change in sensitivity. Validation of the method according to IUPAC recommendations showed suitability and selectivity of the proposed electrodes for the use in quality control assessment of CET in presence of different interferents. Proposed sensors were successfully applied for CET determination in pure form and in its mouthwash where good responses were obtained regarding accuracy and precision.