asghar pirzadeh

More studies showed that diagnosis of cancer lead to occurrence of emotional problems in patient and his family. Fluoxetine is an anti-depression drug that used for treatment of Depression, Obsessive compulsive disorder, Panic disorder and nervous incontinence. The aim of this study was investigate the effect of fluoxetine on quality of life in patients with solid cancers. This is a randomized controlled clinical trial that has been done on two groups of patients each with 70 patients. One group received fluoxetine for 12 weeks and another group received placebo. In baseline and end of study, SF36 questionnaire were completed for all patients and results analyzed by statistical methods in SPSS.16. The most prevalent malignancy in case and control groups was gastric cancer with 40% and 42.9%, respectively. There wasn’t significant difference in QOL of patients in baseline between two groups but in the end of study, emotional-psychological health and vitality scores in case group was better than control group. In terms of physical symptoms and depression, the case group was better than control group. In start and end of study, in QOL score only difference was seen in physical activity which was better in case group than control group. Results showed that fluoxetine prescription in patients could recovery some dimensions of QOL and general health but not effect on some dimensions which probably related to short duration of fluoxetine prescription in patients

Venous thromboembolism (VTE) is one of the three causes of mortality made by cardiovascular disease and pulmonary embolism is the most common preventable causes of mortality among hospitalized patients. Considering high prevalence, the importance of etiologic studies of diseases and different previous reports regarding the role of blood groups on occurrence of diseases such as VTE, this study was carried out to determine the blood groups of the hospitalized patients with diagnosis of VTE. This cross-sectional study was carried out on 200 hospitalized patients with the diagnosis of deep vein thrombosis (DVT) and pulmonary embolism (PE) in Imam, Fatemi and Alavi hospitals in Ardebil. The final diagnosis was made by c olour D oppler ultrasound and pulmonary CT angiography and blood groups and risk factors were determined. Results of this study analysed along with the previous epidemiologic reports related with blood groups in Ardebil and Iran population using chi-square and t-test and SPSS software. Of 200 patients with VTE, 140 patients were affected with DVT and 60 patients with PE. In this study, 92 patients were males and 108 were females. The mean age of patients was 52 ± 19 years. The most prevalent blood group was type A with a rate of 47.5%. There was no correlation between the diseases namely DVT or PE and blood groups (P=0.55). Frequency of type A (OR: 2.914) and B (OR: 1.608) in patients with VTE was more than Ardebil and Iran population but the type O (OR: 0.632) was less than those population. These differences were statistically significant. The frequency of type AB was similar in all groups. The Correlation between blood groups and venous thromboembolism, which have been discussed in many studies, have been investigated in Iran and at medical centres of Ardebil University of Medical Science for first time. It seems the type of blood groups (A and B) is effective in frequency of VTE. More studies are needed on the correlation between blood groups and VTE.

Extramedullary plasmacytomas are rare solitary soft tissue tumors that arise from proliferations of malignant transformed monoclonal plasma cell. Though they are closely related to multiple myelomas, they have better prognosis. The tumor is eradicated by surgery or local radiation therapy. This is a case-report study of solitary plasmacytoma tumor which involved left side maxillary sinus and underwent excisional biopsy confirmed by IHC.