h. darvish

Regulation of gene expression is performed by the promoter sequence resided upstream of genes. There are a group of class II gene promoters which lack any consensus sequences and bioinformatics studies have revealed that the frequency of exceptionally long repeats in these promoters are significantly more than other promoters. One of such promoters is the RIT2 gene promoter which includes an 11 GA repeat and its role in neurologic disorders such as Parkinson’s disease is the aim of this investigation. 

In this case control study we investigated the polymorphism of the GA repeat in 500 PD samples and 500 healthy controls, and also the role of the repeat sequence on gene expression using cloning technique.

We found that the GA repeat of the RIT2 gene shows monomorphism in human population. In expression study, we observed two fold expression level of luciferase in the presence of the GA repeat compared to its absence. 

Due to the important effect of the GA repeat in the RIT2 gene promoter and the important role of RIT2 gene in neuronal development, any alterations in repeat sequence is intolerable for cells and there is a strong conservation for this repeat.

Tiger-toothed croaker (Otolithes ruber) is one of the most important species that currently catch in the Northwest of Persian Gulf. A Generalized Additive Model (GAM) was fitted to Tiger-toothed croaker, Otolithes ruber, CPUE data (kg  per hour) from gillnet based in Northwest of Persian Gulf, Iran, between 2013 and 2018, with the aim to observe their relationship with environmental, spatial and temporal information. GAM model accounted for 36.4% of the variance in nominal CPUE. Stepwise GAM revealed the relative importance of two variables by decreasing magnitude, namely kd490 and month. The maximum and least CPUE rate occurred in Feb 2013 (42.62 kg/h) in Boseif station and November and December 2013 (1.13 kg/h) in Darvish station. This study considered the possible relationship of spatial, temporal and some satellite derived environmental variables on Otolithes ruber CPUE to finally help implementing of ecosystem based fisheries management for stock recovery program and management of this species. Results of this research revealed that latitude and longitude and year sampling have the greatest impact on Otolithes ruber CPUE. Since, the early step in ecosystem management is the sufficient knowledge on ecosystem and distribution of target species in relationship to environmental variables, therefore this research could help to implementing of ecosystem based management in this region.

Accurate and correct performance of controller in cruise control systems is important. Hence, in such systems, controller should optimize itself against noise and probable changes in system dynamic. As a matter of fact, in this article three approaches have been conducted to-ward this purpose MIT, direct estimation and indirect estimation. These approaches are used as controllers to track reference signal. First the performance of each of these three controllers is checked. comparison of performances indicated better behavior for indirect estimation than others. Also, it has less sensitivity against external noise. Finally, by using indirect estimation method as an adaptive control approach, two parallel separate controllers are designed for two inputs, gas and braking, and their performances are compared with recent studies. It shows improvement in performance of adaptive cruise control system to track reference signal.

The aim of thisstudy was to investigate the effect of the emotional intelligence on culture and organizational performance ofEducational Center of East Azerbaijan Agriculture. In this applied study the statistical population consist of 716 staff and students of theEducational Center,out of which 245 were chosen randomly.The reliability of questionnaire was estimated through Cronbach alpha. For the questionnaires of emotional intelligence, performance and organizational culture, the coefficients were x1 =0.823, x2=0.898 and x3= 0.877 respectively. The data were collected and analyzed through structural equations, t-student test, and factor analysis. Results showed that emotional intelligence has significant affect on organizational culture and organizational performance.