negin molazadeh

Kawasaki disease (KD) is an acute, self-limiting vasculitis that predominantly affects children under five years of age. It is recognized as the leading cause of acquired coronary artery disease in this age group.

This manuscript presents two cases of KD complicated by significant coronary artery abnormalities, which ultimately necessitated heart transplantation.

Emphasizing the importance of early diagnosis and treatment, this study underscores the critical need for continued research to improve outcomes for affected patients.

Electrical cardioversion (ECV) is a safe method for the treatment of atrial fibrillation. It seems that left atrial volume index (LAVI) could be a good marker in predicting the success of ECV. The purpose of this study is to assess of the significance of LAVI measurement before ECV in predicting the recurrence of the AF.
Fifty-one patients with AF, selected for ECV were studied in the cardiology department of Tabriz University of medical sciences. The clinical and demographic data of all the patients were obtained. Echocardiography was performed before and also three months after ECV. Patients were separated into two groups: those who maintained SR and those with relapse of AF diagnosed by clinical manifestations and electrocardiography (ECG).
Sinus rhythm (SR) was maintained in 76.5 percent of the patients following the three months after ECV. The age, sex and the body mass index (BMI) were not significantly different between SR and AF groups. Two groups showed no significant differences considering pre-ECV medical history including medications and systemic diseases. The initial LAVI of SR group was 42.21±12.4 mL/m2 and AF group was 96.08±52.21 mL/m2, the initial LAVI was significantly different between two groups (P = 0.000). The LAVI of SR group decreased significantly (5.69±0.74 mL/m2) after three months, LAVI decreased from 42.21 ± 12.4 ml/m2 to 37.51 ± 10.52 mL/m2. (P = 0.000). The cut-off point of LAVI value in predicting the maintenance of SR was 55 mL/m2.
The present study indicates that LAVI is a powerful forecaster of the recurrence of AF after ECV. The LAVI measurement could be a useful method in the selection of the patients with AF for ECV.

Superovulation and in vitro fertilization are widely used in laboratory mice. Different strains of mice have inherent genetic differences that cause them to respond differently to these technologies. In this study, we investigated the effects of superovulation on two different mouse strains. In this basic study, two strains of female mice, Balb/C and NMRI, were superovulated using PMSG and hCG. The resulting oocytes were counted and characterized morphologically and then fertilized in vitro. The following day, two-cell embryos were counted and the results were analyzed statistically. The response to the superovulation treatment varied among strains and ranged from 0 - 20 (Balb/c) to 0 - 60 (NMARI) normal oocytes per female. The number of oocyte (p<0.00) and dead oocyte (p<0.05) showed significant differences between two strains. The other items including fragmented and granular oocytes, and two-cell embryo didnt show significant differences. This study showed the effect of mouse strain response to superovulation. NMARI strain showed a better response to superovulation and in vitro fertilization than Bab/c.