zahra maleki

Uterine cancer ranks among the leading causes of mortality in women, particularly prevalent in countries with low to moderate income levels. Present treatment and healthcare success rates are assessed by the survival rate index. This study aimed to determine the uterine cancer survival rate in Asia.

Five international databases were analyzed to perform this systematic review: Medline/PubMed, ProQuest, Scopus, Web of Knowledge, and Google Scholar, until the end of August 2021. The Newcastle-Ottawa quality assessment form was utilized in the evaluation of quality for cohort studies. “I2 statistic and Cochran test were used to check the analysis process and assess the heterogeneity among the studies. Also, the study year was used as the basis for a meta-regression analysis.

The study covered 75 papers in total. The survival rates of uterine cancer after one, three, five, and seven years are 76.68% (95% CI, 66.76–78.61), 63.56% (95% CI, 58.60–68.37), 59.04% (95% CI, 55.62–62.43), and 57.86% (95% CI, 51.16–64.42) according to the random model. Furthermore, according to the outcomes of the meta-regression, there was no correlation found between the study year and the survival rate.

Compared to European and American countries, Asian countries have a poorer uterine cancer survival rate, which makes it crucial to improve the survival rate of patients through ensuring early diagnosis of the disease in its early stages and providing new diagnostic methods, modified surgical techniques, and targeted therapies.

 Cyclodextrin based nanosponge (CDNS) as a novel delivery system has not been compared in terms of antioxidant and cytotoxicity potentials with its individual components. Given that oxidative stress and cytotoxicity play pivotal roles in various diseases, the authors sought to evaluate the properties of the synthesized CDNSs and their components, β-cyclodextrin (β-CD) and carbonyldiimidazole (CDI). These carriers have been widely used in pharmaceutical sciences for various purposes. Demonstrating their remarkable characteristics can guide researchers in making accurate applications and selections.

 Two types of CDNSs were synthesized with different cross-linker ratios. The analysis involved dynamic light scattering (DLS), differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), and solid-state NMR methods. The antioxidant activity was determined through DPPH scavenging activity, glutathione peroxidase assay, and detection of reactive oxygen species levels. Additionally, the cellular cytotoxicity of the materials was characterized using the MTT test.

 The results confirmed the synthesis of CDNSs with 1:2 and 1:4 β-CD:CDI molar ratios. The antioxidant results revealed that β-CD and CDI exhibited higher antioxidant activity compared to CDNSs with 1:2 and 1:4 ratios. Based on the MTT results, all four compounds demonstrated almost complete cytocompatibility with at least 50% cell viability.

 Following the successful synthesis of CDNSs, it can be inferred that these materials are non-toxic. However, the process of nanosponging did not enhance the antioxidant activity of β-CD and CDI.

As of 2020, prostate cancer is the fifth most common cause of fatalities due to cancer in males and is also the second most common type of cancer overall. The purpose of this study was to look into the patterns of prostate cancer-related mortality and years of life lost (YLL) in the province of Fars.

Data on all prostate cancer-related fatalities in the province of Fars were gathered for this cross-sectional investigation via the electronic population-based death registration system (EDRS). We calculated the crude mortality rate, age-standardized mortality rate (ASMR), years of life lost (YLL), and YLL rate. The JoinPoint Regression method was used to analyze the patterns over time.

During the 16-year study period from 2004 to 2019, there were 1,836 deaths from prostate cancer in Fars province. The crude and standardized mortality rates showed an increasing trend over this period. The total number of years of life lost (YLL) due to prostate cancer during these 16 years was 15,785. The highest number of YLL occurred in the age group of 70-79 years, while the lowest was observed in individuals under 30. According to join point regression analysis, the YLL rate due to premature mortality increased over the 16 years, with an annual percent change (APC) of 2.3% (95% CI 0.2 to 4.4, p=0.034).

Prostate cancer-related death and YLL are on the rise, according to the study's findings. Therefore, it is necessary to improve diagnostic and therapeutic measures; more studies in this field are also recommended.

The effect of COVID-19 vaccination coverage on the role of social capital as an essential dimension in disease prevention is undeniable. This study investigated the correlation between Covid-19 vaccination coverage and social capital. This ecological study used aggregate data from 130 countries. A fully vaccinated index was used to cover the COVID-19 vaccination. The main variable was the cumulative fully COVID-19 vaccinated population share data, which was retrieved from Our World in Data repository. The data related to social capital was retrieved from the global sustainable competitiveness databases. Cumulative fully vaccinated population shares related to COVID-19 were 46.83%. The higher rate of cumulative fully vaccinated population shares related to Covid-19 was reported in the United Arab Emirates (90.28%), Portugal (88.98%), and Singapore (87.00%), and also the lower rate of cumulative fully vaccinated population shares related to Covid-19 were reported from Burundi (0.02), Chad (0.48), and Haiti (0.61). There was a positive significant association between cumulative fully vaccinated population shares and social capital (r=0.74, p<0.001). A positive significant association between cumulative fully vaccinated population shares and social capital was found in 39 high-income countries (r=0.33, p=0.03), 36 upper-middle-income countries (r=035, p=0.04), and 36 lower-middle-income countries (r=0.51, p=0.002). A strong positive association between cumulative fully vaccinated population shares and social capital in the countries was observed. Appropriate interventions are needed to increase the level of social capital and its components in countries to increase access to vaccination and health status in countries in the conditions of a pandemic.

Impulse waves are among the natural phenomena that are caused by the impact or transfer of energy from a mass to still water. These waves are widely observed in nature and engineering environments and have multiple effects on the surrounding structures and environments. Masses’ sliding into still water is one of the common situations in creating impulse waves that can occur in different scenarios, such as floods, landslides or sudden entry of materials into water. In recent years, many researches have been conducted in this field, each of which has investigated specific aspects of this phenomenon. The importance of studying impulse waves, especially in the fields of marine engineering and environmental protection, is clearly visible. These waves can cause serious damage to marine structures and aquatic ecosystems, and for this reason, a more accurate understanding of their characteristics and behavior can be effective in better design and more appropriate management of these environments. This article was written with the aim of providing a comprehensive framework for future research in this field. Presenting a comprehensive review of the studies conducted in the field of impulse waves caused by the sliding of masses into still water. In this regard, the results of various tests, data analysis and comparison of the results will be discussed.

The phenomenon of impulse waves caused by soil mass sliding into water is one of the important issues in geotechnical and hydrodynamic engineering, which can have destructive consequences on the environment and coastal structures. These waves are widely observed in nature and engineering environments and have multiple effects on the surrounding structures and environments. These waves are caused by the sudden entry of the soil mass into the water, and their investigation is of great importance, especially using numerical methods. In this study, a comprehensive review of the numerical researches conducted in the field of impulse waves caused by landslides is presented. This article examines different numerical models, key parameters affecting wave generation and validation of numerical results compared to experimental data. Also, the challenges in the numerical simulation of this phenomenon and the proposed solutions to improve the accuracy of the modeling have been investigated. The results of this study can help to improve the understanding of this phenomenon and develop new simulation methods.

In recent years, metakaolin is used in concrete to improve the short-term and long-term properties of concrete. Considering the importance of compressive strength and bonding between concrete and rebar in reinforced concrete structures, a new method for evaluating bonding strength between concrete and reinforcement is presented in this research. Also, the optimal percentage of metakaolin along with steel fibers has been determined in order to achieve maximum bonding and compressive strength. In this research, 20 different mixing designs with four different percentages of metakaolin (0%, 10%, 15% and 20%) and five different percentages of steel fibers (0%, 0.75%, 1%, 1.5% and 2%) were considered and slump test on fresh concrete and compressive strength and bonding strength tests on 28-day samples were conducted. The results showed that the new method presented for measuring the bonding strength between concrete and rebar is very practical. Also, minor addition of metakaolin and steel fibers significantly reduced the compressive strength, and by increasing the percentage of fibers, the compressive strength was increased and then decreased. Also, adding metakaolin up to 15% significantly increased the bonding strength of concrete, but by increasing the amount of metakaolin up to 20%, bonding strength of concrete was decreased. On the other hand, both metakaolin and steel fiber reduced the flowability of fresh concrete. Finally, the sample containing 15% metakaolin and 1.5% steel fibers showed the highest bonding strength.

In the current era, following the occurrence of environmental crises, the destruction of resources and the creation of obstacles on the way to sustainable development, it is necessary to carry out programs based on the recognition and assessment of ecological potential so that exploitation in It should be fed continuously from the environment and the natural values of the environment should be preserved. Therefore, after formulating development strategies and implementing social economic programs, geographical survey of the region and recognition of its environmental capabilities and then determining the ecological potential of the land for different uses with the aim of continuous exploitation with the least Destruction and preservation of the environment is an inevitable necessity. The ecological capacity of the land allows the planner to determine the direction and solutions of the region's development based on the region's capabilities, and provide a plan that fits the conditions of the region. Evaluation of the ecological potential is an effective step and a suitable tool to direct the current activities and uses in the land towards sustainable development. FAO defines "land suitability assessment" as an assessment process that considers the performance of land when used for a specific purpose. The assessment process is directed towards optimal land use by providing important information about the opportunities and constraints in using a given land.

According to the review of various library sources as well as the conditions of the region, 10 criteria of Elevation, slope, Aspect, distance to main roads, distance to waterways, distance to fault, distance to landslide points, distance to flood plains, Normalized Difference Vegetation Index (NDVI) and land use were investigated as different criteria for capacity measurement. To study the capacity of the studied area and to prepare suitable areas for the development of Ecotourism, the following steps were carried out; A): Assessment of land suitability to check the capacity of the region for tourism development using the MCE method First step) defining the set of evaluation criteria (information layers),  The second step) standardizing the criteria, The third step) defining the weights of each criterion, Fourth step) preparation of the final map: in the last step, the obtained weights were multiplied in the required layers and then added together. The fifth step) using the final desirability layer produced at the end of the fourth step, places that have a higher value than other areas, using the location method based on suitability and area (ZLS) as suitable places. They are selected for the development of nature tourism. B): Selection of the most important socio-economic parameters and ranking of the spots: the values of these indicators were extracted for the selected spots and at the end, the rank of each spot was determined using the TOPSIS method.

The results of the AHP questionnaire show that the Criteria of slope, Elevation and NDVI are the most important Criteria affecting the development of Ecotourism in this region. The results obtained for the development of Ecotourism in the studied area show that 21,269 (8.63%) hectares of the area are without capacity, and 6634 (2.70%) hectares are of the area with very high capacity. Due to the fact that a minimum area is required for the development of concentrated Ecotourism, in this study, seven areas with areas of at least 100 hectares were selected from the very high capacity category. Based on the results obtained from the AHP method, respectively, the indicators of the diversity of the area, the amount of pristine, the distance to road, the total population within 5 kilometers of the area and the average suitable map have the most importance on the selection of the best area for the development of Ecotourism. The results of the TOPSIS method show that region 2 is the best place for the development of Ecotourism in this watershed with a score of 0.8188. Then regions 5 and 1 were selected as the second and third regions with scores of 0.7868 and 0.6506 respectively. The places with the lowest rank are regions No. 4 and 3 with a score of 0.3197 and 0.0464 respectively.

Among the different capabilities of each region, tourist attractions are one of the most important natural resources in each region, and are important factors in attracting tourists and attracting capital, and thus are the main basis for sustainable development for the region. The results of the survey show that all three selected final regions are in the central part of Noor city and region 2 has the largest area (370.759 hectares) in terms of area. Also, according to the average map, it is equal to 0.928 and in terms of access, it is 144 meters away from the main road, and its virginity is 80%. Various studies (Balist et al., 2019), (Zarei et al., 2013), (Pour Ahmed et al., 2013) in the world show the superiority of this model (the combination of AHP method and TOPSIS method) over other models confirmed in their studies.

It seems that the study and investigation of topographical landforms and the pattern of the drainage network system, based on geomorphic indicators, can evaluate the status of active tectonic performance. However, the basic structure of the earth, the type of rock and the local factors that determine the microclimate are not taken into consideration. Asymmetry factor (AF) is used to measure the asymmetry of the drainage basin. This research was conducted with the aim of evaluating the tectonic activity of Golpayegan area using the asymmetry index of the drainage basin. The scope of this research is located in the Golpayegan area and in the structural zone of Sanandaj-Sirjan. The results obtained from the research show that Gudjan, Shah Enayat, Hazar Jarib Gharbi, Chehlkhane, Vanshan Gharbi and Vanshan basins are classified in tectonic class 1 and the rest of the basin in class 2 (moderate) to class 3 (relative tectonic activity) below) are shown. The calculated values ​​of the transverse topographic symmetry index are in good agreement with the calculated values ​​of the asymmetry index, and the values ​​related to the asymmetry index confirm well the values ​​of the transverse topographic symmetry.

Given the strategic importance of pure titanium in sensitive industries, such as healthcare, and the existing weaknesses in the mechanical and physical properties of this metal, the present study aims to investigate the enhancement of its mechanical properties through the composite fabrication of pure titanium with Reduced Graphene Oxide (RGO) nanoparticles based on Spark Plasma Sintering (SPS) method. During the fabrication process, the mechanical properties of the samples were evaluated and compared using specialized tests. Composite fabrication is one of the effective and common methods for improving the material properties. As demonstrated in the results obtained in this study, the SPS method can be proposed as a reliable method for producing high-quality composites. Further evaluation of the mechanical properties of the samples reinforced with RGO indicates that the optimal presence of this reinforcement significantly enhances the mechanical properties compared to those of the pure samples. Moreover, the analysis of the behavior of the produced samples during the sintering process indicates a significant increase in the force and pressure in samples containing reduced graphene oxide, with no observed significant changes in displacement and temperature.

Oil contamination of soil is a significant environmental issue that various countries, including Iran, have encountered. Leakage and the spread of oil contamination in different sectors of the oil industry, such as oil production areas, refineries, and transportation lines, lead to extensive soil contamination. The physicochemical processes occurring between the pollutant and the soil alter the geotechnical behavior of soil. Nanoparticles, due to their small size and filling properties, can enhance soil density and resistance. This article investigates the impact of nano-clay as a novel additive on gasoline-contaminated soils, revealing that with increasing contamination levels, both optimum moisture content and maximum dry density decrease. Moreover, higher contamination percentages result in reduced soil plasticity limits; as gasoline content increases, the Atterberg limits decrease. Hence, Therefore, in order to achieve greater soil resistance, adding different clay nanoparticles with percentages of 0.25, 0.5, 1 to the soil contaminated with diesel oil increases the amount of leaf ether and hardens the soil.

There are various methods to prevent river bank erosion, one of them is groin. These structures are used to control the natural movement of the bed and reduce the movement of sediments by reducing the power of the water flow. Groins are divided into permeable and impermeable types, the permeable form of which is used in rivers where the amount of suspended load is high. By reducing the speed of the flow in the groin field, the sedimentary materials are quickly deposited. This process and then creating a thick sedimentary layer, keeping the erosion flow away from the groin area and it provides the stable conditions necessary to protect the banks. In this study, the performance of parallel permeable groin and single permeable groin has been compared. For this purpose, a flume with a length of 5 meters, width of 30 cm and height of 30 cm has been used. Experiments have been conducted with 60 and 40% permeability rates in clear water conditions, and the observations from the experiments have been made in relation to the maximum scour depth and the changes in the topography of the flume bed have been compared.

Groins are one of the ways to protect river banks against erosion. These structures prevent their erosion by diverting the flow from the river bank. In this study, a new arrangement of permeable groin is presented, which are called radial groin. In order to investigate the behavior and performance of this type of groin, a flume with a length of 5 meters, width of 30 cm and height of 30 cm was used. The experiments were conducted with a permeability rate of 60% in clear water conditions and in the back to the flow state, and the observations from the experiments were made in relation to the maximum scouring depth and the changes in the topography of the flume bed with straight and parallel arrangement of scours with the same permeability has been compared. The results show that the radial arrangement has performed better than the parallel and direct arrangement and has been more successful in creating scour pits with less depth.

In a laboratory study, a new arrangement for permeable groin has been presented in which the form and number of groin bars are different compared to the conventional direct form, and the effect of this new arrangement on the maximum depth of the scour hole was investigated at the groin nose. The permeability values of the groin group are considered equal to 40, 60 and 80% and the tests were performed in clear water conditions. The flow rate and bed conditions are considered the same in all tests and the behavior of groin to deal with local scouring of the nose under the change in permeability and the number of bars in the groin group in both radial absorbing and direct forms has been investigated and compared. The results show that among the tests conducted, the maximum depth of the erosion hole decreased with the increase in permeability, and also the performance of the provided radial absorbent arrangement is better and more effective than the direct arrangement in controlling the maximum depth of the erosion hole.

The scouring phenomenon is one of the issues that are always important in the design of various types of hydraulic structures; among these structures is the groin. These structures prevent their erosion by diverting the flow from the river bank. The flow mechanism in rivers at the locations of groin is such that the bed of a river undergoes changes and erosion over time. In this study, the performance of the permeable radial groin with different numbers was investigated. Also this groin was comparison with the double and single direct permeable arrangement. For this purpose, a flume with 5, 0.3, 0.3 meter long, wide and high was used, respectively. The experiments were conducted with a permeability rate of 40% in clear water conditions. The observations from the experiments regarding the maximum scour depth created in the flume bed show that the number of groin in a radial arrangement has an effect on the maximum scour hole depth.

The construction of water structures such as groin is done to protect the beaches and prevent their erosion. These structures disrupt the uniform regime of flow and sediment transport. In most cases, these conditions lead to local scouring of the bed. In order to protect the bed and minimize the depth of the scour hole, various arrangements for the groins have been proposed and tested. In this study, the influence of the angle of circulation in the radial arrangement of the permeable groin and its comparison with the direct permeable groin has been investigated. For this purpose, a flume with a length of 5 meters, a width of 30 cm and a height of 30 cm was used, and tests were performed with three different permeability rates of 40, 60 and 80% in clear water conditions. The results show that in the radial arrangement, the maximum depth of the scour hole at the toe of the groin and its width have decreased compared to the direct arrangement, and the radial arrangement has a better performance to prevent the erosion of the river bed.

One of the solutions for architecture sustainable development is industrial implementation of buildings systems with sustainable architecture principles. Industrialization is increasing the use of human resources, raw materials and capital in order to respond to the housing needs of the society and economic productivity by using new and sustainable technologies that are organized and coherent in a regular and modular structure. Today, with the development in the construction industry and the ever-increasing need to buildings, we need solutions with the goal of sustainable architecture planning, management and coordinated growth of related industries. In this research, the introduction of Tronco system, its construction method and technical specifications including structural elements, architectural features, safety and its strengths and weaknesses have been discussed. With regard to sustainable urban development, it can be concluded that the Tronco system has the ability to become a sustainable system. Also, this system has a favorable level of energy consumption optimization and brings sustainable development in architecture.

The influence of academic support on students’ academic and personal development has been previously demonstrated. Therefore, this research conducted with the aim of validating the Persian version of the Perceived Academic Support Questionnaire (PASQ) for adolescents. Four hundred adolescents (200 girls and 200 boys), selected using a convenience sampling method, responded to the Perceived Academic Support Questionnaire (Reyes & et al., 2022), the Academic Interest Scale for adolescents (Luo & et al., 2019), the Brief Regulation of Motivation Scale (Kim & et al., 2018) and the Motivational Persistence Scale (Constantin & et al., 2012). The results of the confirmatory factor analysis showed that the PASQ had good factorial validity with a three-factor structure consisting of academic support from teachers, family, and peers. In addition, the results related to the correlation between the dimensions of academic support with motivational regulation, motivational persistence and academic interest supported the criterion validity of the Persian version of the PASQ. The results of multi-group confirmatory factor analysis revealed the cross-group invariance of factorial structure, factor loadings, and factor variances and covariances of the PASQ across male and female adolescents. Internal consistency for the academic support from family, teachers and peers subscales was 0/90, 0/83 & 0/83, respectively. The validation results of the Persian version of the academic support questionnaire for adolescents showed that this scale has good validity and reliability and can used in future studies

Based on the research results and tectonic indicators, the region is in an average tectonic state. One of the threatening factors in the region is the effect of the Minab fault on the rise of the region, which increases the slope of the region in the northern parts. This, in turn, causes an increase in water flow and flooding of rivers in the downstream areas and causes slope instability and landslides in the region. The purpose of this research is to provide valuable insights about the influence of the geological structures of the region on the future geological and environmental challenges. By calculating morphotectonic parameters and morphometric indices in order to estimate the tectonic risks of Minab fault, its role on geological-environmental risks has been discussed. Based on this, the effect of the Minab fault on the rise of the region can increase the slope of the region in the northern parts and lead to an increase in water flow and river flooding in the downstream areas. This can cause slope instability and landslides in the region. In terms of tectonic risks, the existence of the Minab fault and its related tectonic activity can lead to various tectonic risks, including earthquakes. As a result, while the Minab fault and related tectonic activities can create significant environmental challenges, with proper planning and understanding of tectonic conditions, these challenges can be reduced and lead to sustainable development. The area helped.

Employees' work behavior patterns are associated with their psychological status, especially in the face of work stressors. Among employees with healthy and unhealthy work behavior patterns, the present study aimed to compare psychological disorders and their symptoms in an industrial organization in Mashhad. Through convenience sampling, 144 employees were selected and responded to demographic information questionnaires, work-related behavior and experience patterns questionnaire (AVEM), and Symptom Checklist-90 (SCL-90). Data analysis was performed using a one-way analysis of variance in SPSS software version 26. The findings indicated that psychological symptoms and disorders were significantly higher in employees with unhealthy work behavior patterns, especially the burnout pattern, than in employees with healthy work behavior patterns. The findings highlight the importance of focusing on the mental health of employees who adopt unhealthy work behavior patterns in the face of occupational stressors. In line with existing research evidence, psychological intervention programs that include training in adopting healthy work behavior patterns and enhancing mental health impact employees' well-being and demand further research. Developing and implementing prevention policies and mental health programs in the workplace in favor of employees' well-being is associated with increased organizational productivity and community welfare.

The Zagros fold-thrust belt's Fars region is crucial for the placement of enormous gas reserves in Permo-Triassic carbonate sediments. Therefore, it's important to investigate the potential impact of the Hendurabi fault on the expansion of hydrocarbon traps in the inner Fars region. This will help advance the exploration goals of hydrocarbon materials. The study area is located in the inner Fars region of the Zagros thrust belt. In this research, maps of equal thickness have been prepared, analyzed, and evaluated based on drilling well data in the region, using ArcGIS software. Given the importance of changes and evolutions of the hydrocarbon system in the exploration of hydrocarbon resources, the function of the main basement faults with the role of controlling the bottom of the sedimentary basins, along with the changes that have occurred, can change the nature of a hydrocarbon system and the created hydrocarbon traps. Overall, the activity of the Hendurabi fault has caused thickness changes on the sides of the fault, confirmed by the uplifts and subsidence’s created on the sides of the Hendurabi fault at the same time as the deposition of some formations such as Dashtak. The activity of this fault as a controlling fault of the sedimentary basin floor during the sedimentation of formations like Dashtak is confirmed. Based on the obtained results, the southeastern area of the studied area, containing hydrocarbon traps, is suitable for exploration due to the adequate and appropriate thickness and suitable depth of the Kangan reservoir horizon and Dashtak caprock.

One of the most important things in decision-making and economic growth is the existence of quality, correct and reliable information. A significant amount of this information can be extracted from the accounting information system and financial statements. Financial statements provide a real and visible picture of the real business situation of a given company. It is important to pay attention to financial statements as a model for decision making. that different users should know how to benefit from this information. Managers should be proficient in accounting science so that they can make the best decision from the information collected by accountants. The contents of financial statements provide a large number of different tools and analysis, a way to understand the business. Access to financial statements and financial information is one of the important assumptions of quality and successful business.

In addition to higher carrying capacity, ballastless railways require lower maintenance costs than ballasted ones. Nevertheless, the rail seat abrasion (RSA) is one of the most important factors of damage to the slab railways. In this study, the effect of RSA on the performance of prestressed concrete slabs has been investigated using finite element method. For this purpose, the loss of prestressing force without considering abrasion, abrasion of 5.12, 25 and 37.5 mm with different values of loss of prestressing force, abrasion of 5.37 mm with different values of compressive strength and different values of abrasion along with the removal of prestressing force in the longitudinal direction in the structure has been checked. The results showed that due to the linear behavior of concrete under the range of loading and the absence of cracks in the structure, changes in prestressing force, removal of prestressing force in the longitudinal direction have minor effect on the mid-span displacement (<2%). However, with increasing the prestressing force drop from 10% to 20%, the displacement is reduced by 50%. In general, it can be found that increased abrasion reduces the capacity of railway. The effect of increasing the abrasion on the maximum mid-span displacement in prestressed concrete slab line is not linear and the higher the amount of abrasion, the greater the amount of displacement increases.

Development refers to the progressive enhancement of skills and functional capacity, i.e., qualitative changes in the child’s functions. The process of development begins before birth and continues throughout life. The present study aims to evaluate the effectiveness of the “Care for Child Development (CCD)” program on 4-42 months children’s developmental skills in orphanages.

In this study, two orphanages in the capitals of East and West Azerbaijan provinces were selected using the convenience sampling technique, and thirty children were included. Then, they were randomly divided into two intervention and control groups (each group, N=15). Next, after obtaining consent from the head of the orphanages, a group of volunteers from the healthcare center performed the CCD program, considering children’s chronological ages (4 to 42 months), for three sessions a week, with each session lasting two hours and it lasted for three months. At the end of the intervention process, the Bayley Scale of Infant and Toddler Development 3rd version (BSID-III) and the Ages and Stages Questionnaire-II (ASQ) were completed for the two intervention and control groups to compare them in the cognitive, motor, communication, and personal-social domains.

Comparing the two control and intervention groups using the T-test (difference in mean) indicates that except for the domain of cognitive skills (Bayley: P-value = 0.176), there was statistically a significant difference between the two groups in communication (ASQ: P-value= 0.001; Bayley: P-value = 0.003), motor (ASQ: P-value = 0.000; Bayley: P-value = 0.009), and personal-social (ASQ: P-value <0.000)skills.

In the present study, it was concluded that it is required to apply interventions, including standard ones such as the CCD program in environments like orphanages, to enhance the developmental skills of those children living in them

In this research, the deposits of the Oligocene-Miocene Qom Formation in Kuh-e Charkheh (Natanz), Western Zefreh and Varton sections, northeastern Isfahan were studied. According to the field observations and thin section analysis in Carbonate part of the mentioned sections, 8 microfacies were identified, which were deposited from shallow part of lagoon to open marine and the sedimentary environment of 3 sections due to absence of reef and presence of bioclastic barrier and absence of spillage, the homoclinal carbonate ramp was detected. According to the sequence stratigraphic studies, each of the studied sections has two 3rd sequences. In Kuh-e Charkheh section, both sequences include of TST and HST, which are separated by sequence boundary SB2. In the western Zefreh section, the first sequence includes of TST and HST that is separated from the second sequence (include of LST, TST and HST) with sequence boundary SB1. In the Varton section, the first sequence is aggredation type and separated from the second sequence, which include TST and HST by a sequence boundary SB2.