جستجوی مقالات مرتبط با کلیدواژه « ApoA » در نشریات گروه « تربیت بدنی »

Back grand: Early obesity and its transfer to the adult, increases likelihood incidence of coronary artery disease (CAD). ATP-binding cassette transporter) ABCA1) as a member of the ABC transporters family plays a crucial role in reverse cholesterol transport and CAD prevention. The purpose of this study was to investigate ABCA1 expression in lymphocytes, plasma apolipoprotein A-I and lipid profiles in response to eight weeks interval aerobic endurance exercise as rope training. Thirty students (17.3±1.1yr, 85.73± 11.68 kg and 28.41± 2.36 kg / m²) volunteered and randomly were assigned into training (n = 15) and control (n =15) groups. Exercise protocol was endurance rope training (8 wk, 4 d/wk and 40 min/d). cell hemolysis and sensitive Elisa method was used for Lymphocyte ABAC1 protein expression.T-student test was employed and data were analyzed by SPSS software (version 16). The independent-samples T-Test results were showed that after 8 weeks interval rope endurance training, the levels of lymphocyte ABCA1 expression(p=0/000) and VO2max(p=0/000) were significantly increased and plasma levels of TG(p=0.017), TC(p=0.001), LDL-c/HDL-c(0.026),TC/HDL-c(p=0.002) and measures of BF%(p=0/015)and BMI(p=0.042) as anthropometric indicators were decreased. Changes of other variables such increasing in Apo A-I, HDL-c, LDL-c and decreasing in body weight, were not significant. Significant level (p>0.05) was considered. The findings of this study proved that 8-week interval aerobic endurance exercise as rope training can be have positive effects on lymphocyte ABCA1 protein expression(as goalkeeper of reverse cholesterol process) and lipid profiles and ultimately in prevention of arteriosclerosis among overweight and obesity adolescents.

Adipocyte fatty acid-binding protein (A-FABP), a member of FABPs family, plays an essential regulatory role in energy metabolism and inflammation, and apolipoprotein A-1 (apoA1) is the major HDL-associated apolipoprotein. The purpose of this study was to investigate the effect of resistance training with progressive load on serum A-FABP and apoA-I levels. Sixteen male Wister rats (12-14 weeks’ old) were randomly divided into control (n=8) and training (n=8) groups. The training group was subjected to a resistance training program with the use of a ladder (3 days/wk, for 4 wk). Fasting serum levels of FABP and apoA-I concentrations and lipid profile levels in serum and liver were measured. After four weeks resistance training serum FABP and apoA-I levels in training group were significantly higher than control group (respectively, P= 0.026 & P= 0.028). We did not find any significant difference in serum and liver lipid profile between groups. These results indicated that resistance training with suitable intensity could increase serum A-FABP and apoA-I levels.