جستجوی مقالات مرتبط با کلیدواژه « Propargylamines » در نشریات گروه « علوم پایه »

Propargylamines derivatives have been reported to possess a wide range of pharmaceutical activities or can be converted to some compounds with similar properties In this project, sulfamic acid stabilized on silica coated Fe3O4 magnetic nano particles was prepareded and characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), thermal gravimetric analysis (TGA). Then this catalyst used as a magnetically retrievable catalyst in the synthesis of different propargylamines by the reaction of various aldehydes, secondary amines and terminal alkynes at 80 °C under solvent-free conditions in high yields. This method is not only high yields and low cost due to solvent free conditions, but also due to having magnetic core catalyst can be easily separated using an external magnetic field and reused up to five times. It is worth noting that the difference in yields between the first and fifth catalyst recycling was less than 12%.

In this report for the first time, gold nanoparticles were supported and stabilized on copper ferrite nanoparticles (CuFe2O4 NPs) and obtained compound was characterized by different techniques such as transmission electron microscopy (TEM), X-ray spectroscopy (EDS) mapping, X-ray photoelectron spectroscopy (XPS), thermogravimetric analysis (TGA) and X-ray diffraction (XRD) . Novel prepared material has been applied as a bimetallic and magnetic catalyst in successful coupling reaction of structurally different aldehydes, amines and alkynes for preparation of various propargylamines. Using this catalyst, corresponding propargylamines were obtained in high to excellent yields. Catalyst was successfully recovered by external magnetic field and reused for 6 consecutive runs without decreasing of activity.