The response of serum Angiopoietin-like protein 8 (ANGPTL8) levels to acute exercise in physically active young men

Aim: Angiopoietin-like protein 8 (ANGPTL8) is a hepatocyte-derived circulating factor that regulates plasma triglycerides levels. The purpose of this study was to investigate the response of serum ANGPTL8 levels to acute exercise in physically active young men..
Eleven healthy, active young males (aged 24±3.63 years, BMI 22.98±2 kg/m2) volunteered for this study. Acute exercise protocol comprising 2 series of 6×10 s sprinting cycling with maximal effort and 10 min active rest (cycling with intensity 65%–75% HRmax).Blood samples were obtained at fasting state, pre-exercise (30 min after breakfast ~365 kcal), immediately, 15, 30 and 45 min after exercise for measuring serum variables. The repeated measures of ANOVA and Bonferroni post-hoc test used to evaluate changes of parameters in the different times. The relationship between variables was assessed using the Pearson correlation coefficient.
The results of present study showed that ANGPTL8, glucose, insulin, lactate, TG and LDL-C levels significantly changed in any time courses of this study (p