Enhancement of Hydrophilicity in Poly-lactic Glycolic Acid Electrospun Nanofibrous Web

In this study plasma technology was applied on poly-lactic glycolic acid scaffolds to improve their hydrophilicity. The structure of nanofibrous web is modified using a high speed collector is electrospinning process. The general electrospun scaffold was compared with two types of plasma modified and structure modified scaffolds in hydrophilicity view point. Two types of solvents were used for electrospinning solution. The first was pure chloroform and the second was chloroform-dimethyl formaldehyde. We found that the samples that were electrospun with higher collector speed show lower contact angle and consequently higher hydrophilicity. The high speed of collector causes an aligned and regular web formation that improves the hydrophilicity of the electrospun nanofibous scaffold. The results of ATRFTIR spectra showed that the samples modified by plasma shows enhancement in C=O and C-O groups that can be the reason of hydrophilicity enhancement of scaffolds.