Evaluation of antibiotic resistance in pediatric urinary tract infection during 2016-2017 in Shahid Beheshti university hospitals

Urinary tract infection (UTI) is one of the most common and important diseases in childhood, and if it not be diagnosed and treated properly, it may lead to some complications such as acute pyelonephritis, renal scaring and renal failure. Nowadays, the antibiotic resistance rate has been increased because of unnecessary antibiotic consumption. In order to prescribe an appropriate drug as empirical therapy, it is necessary to know about prevalence rate of pathogenes causing UTI and their antibiotic resistance rate in the community. So we attempted to present an appropriate guideline for UTI empirical therapy by evaluating the rate of antibiotic resistance in hospitalized patient’s samples, suffering from UTI.

Materials & methods:

This was a retrospective descriptive analytical study on 130 children with UTI during 2016-2017 in Shahid Beheshti University hospitals who had antibiogram in their medical records and the relative information was recorded and analyzed.

In these 130 patient’s sample, 73/07% were girls and 26/92% were boys. About 50 % of patients were under1 year old, 33/07 % were 1-3 years old and 16/15% were over 3 years old. The detected pathogens were: E.coli 63/07%, Enterococcus14/61%, Klebsiella 13/07%, Pseudomonas aeruginosa 5/38%, Entrobacter 3/84%.

Based on the data of the present study, prescribing Ampicillin, Co-trimoxazole and First generation Cefalosporins are not appropriate enough in UTI empirical therapy.