Heparin Resistance During and Post-Intravenous Nitroglycerin Infusion
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Nitroglycerin has been reported to reduce activated partial thromboplastin time (aPTT) values in patients treated with concurrent heparin and nitroglycerin. However, studies have yielded conflicting results. To determine whether intravenous nitroglycerin alters the anticoagulant effect of heparin, we prospectively evaluated twenty patients admitted for coronary angioplasty by measuring their aPTT both before initiation and after addition of nitroglycerin to heparin therapy. The results showed that the mean of aPTT at the baseline when patients were on heparin alone was not significantly different from aPTT measured upon addition of nitroglycerin, and 30 min following the cessation of nitroglycerin infusion, when patients were still on the same dose of heparin. Therefore, no direct effect of nitroglycerin on the anticoagulant effect of heparin was observed in this study. Keywords: Heparin; Nitroglycerin; Resistance. Received: April 5, 2005; Accepted: May 29, 2005
Keywords:
Language:
English
Published:
Iranian Journal of Pharmaceutical Sciences, Volume:1 Issue: 2, Spring 2005
Pages:
77 to 80
magiran.com/p2131090
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!