Investigation of the Association between FGL1 Expression and Prognosis in Gastric Cancer Patients

Gastric cancer is the fourth most common cancer worldwide, and it ranks second leading cause of cancer deaths. Several studies have shown that FGL2 contributes to the pathogenesis of a number of infectious diseases. However, little is known about its biological functions in cancer development and metastasis. In this study, the association between FGL1 expression and prognosis was investigated in GC patients. Gastric cancer and adjacent normal tissues (n=20) were obtained from patients diagnosed with gastric cancer aged between 30 and 50. Total RNA was extracted, reverse transcription and qPCR were performed, and Relative expression level was calculated using the 2-∆∆Cq method. It was found that FGL1 expression in gastric cancer tissues was obviously higher than adjacent tissues at mRNA levels (P<0.003).