Synthesis of Fe(acac)3 nanoparticles as a modifier of carbon paste electrode for detection of acetaminophen

In the present work, a carbon paste electrode modified with tris (acetylacetonato) iron complex (Fe(acac)3) nanoparticles was used to fabricate a novel electrochemical sensor for the electrochemical determination of acetaminophen (AC). The synthesized Fe(acac)3 nanoparticles was characterized by Fourier transform infrared (FTIR) spectroscopy and the surface morphology and elemental composition of the fabricated electrode were analyzed by  field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray spectroscopy (EDS). Cyclic voltammetry and differential pulse voltammetry methods were used for evaluating the electrochemical behavior of the modified electrode. To optimize the measurement conditions, the effect of various parameters such as pH, deposition time, scan rate, potential, time, and interferences were successfully monitored. The modified electrode enhanced the peak currents relative to the bare carbon paste electrode. Moreover, the proposed electrochemical sensor showed good agreement with previously reported methods and was effectively employed for the quantification of acetaminophen in blood serum.