The Effect of 8-week Resistance Training on Preptin, Irisin and Insulin Resistance in Obese Women

The aim of the present study was to determine the effect of 8-week resistance training on irisin, preptin and insulin resistance in obese women.

In this quasi-experimental study, 20 obese women aged 30-45 years were selected and randomly divided into two groups of resistance training (n = 10) and control (n = 10). The method of the study was that 24 hours before the beginning of the exercises, the individual characteristics of the subjects and the research variables (insulin resistance, Glucagon-like peptide-1(GLP-1), Dipeptidyl peptidase-4 (DPP-4)) were measured in the pre-test. Subsequently, the subjects in the resistance training group performed their training program, which was initially 1RM using the Berziki formula. Subjects then began their workouts for 8 weeks, three sessions per week at 40% intensity and 5 repetitions in the first week, and gradually increased intensity to reach 90% at week 8 with 5 repetitions. Paired-sample t-test, two-way ANOVA and Bonferroni post-hoc analysis were used for data analysis.

The results showed that  resistance training had an effect on the levels of peptin, irisin and insulin resistance in obese women. Resistance training, time, and the interactive effect of exercises and time have an impact on the levels of preptin, irisin, and insulin resistance in obese women( p=0.01). There was also a significant difference between pre-test and post-test on one hand and exercises and no practice on the other(p=0.01)

According to the findings of this study, it can be suggested that resistance training can be a suitable solution to weight control and obesity and prevent their complications.