Architectural fabrication of multifunctional janus nanostructures for biomedical applications

The domain of Janus nanoparticles (JNPs) has seen a surge in research and development during the last decade. JNPs are anisotropic composite innovations with remarkable characteristics that depict a peculiar class of particles, which integrate the features and functions of multiple materials into a single unit. Janus particles are superior prospects for several high-end applications due to their possible modifications by “click chemistry”. JNPs offer new possibilities by combining the features of components. Janus nanoparticles can pack multiple pharmaceuticals and imaging contrast agents simultaneously since they have a distinct chemical configuration on different sides. As a result, they become ideal for administration and bioimaging at once. They have sparked interest due to their exceptional architecture and their potential implications in science and engineering, biological application, and most notably, theranostics. The emphasis of this review is on the latest advancement in the fabrication and implementation of innovative Janus nanoparticles, along with their spectacular performance in therapeutic delivery applications.