Vitamin D in Mild to Moderate COVID-19: A Retrospective Cross-Sectional Study

Vitamin D linkage with COVID-19 is investigated in many studies, but there is still no single summation. Thus, this study aimed to evaluate the relationship between Vitamin D levels and clinical characteristics of COVID-19.

This was a retrospective cross-sectional study on floor admitted COVID-19 patients in the Jahrom province of Iran in 2020. The patients in this study were divided into different groups based on vitamin D status after the definitive diagnosis of COVID-19. Demographic and clinical characteristics of COVID-19 patients were analyzed based on the COVID-19 status. 

Vitamin D levels were normal for almost half of the patients (51.7%) and the rest were insufficient (25.9%) or deficient (22.4%). Serum vitamin D levels did not correlate with vital sign data and venous blood gas results (P> 0.05). Vitamin D status was not different among patients with different symptoms of COVID-19 (P> 0.05).

Our results revealed that vitamin D levels is not correlated to clinical characteristics in COVID-19 patients. In addition, well-designed studies with a good sample size are required to draw conclusions.