Design and Simulation of Two-Dimensional Photonic Crystal-Based Sensor for Detecting Colon Cancer Cells

Designing and simulating two-dimensional photonic crystal-based biosensors is essential for the early and accurate detection of cancers. These biosensors can measure changes in the refractive index of cancer cells, which occur due to the increased concentration of proteins in these cells. In this research work, two-dimensional photonic crystal-based biosensors with dielectric rods made of germanium designed and simulated. The results indicate that the designed two-dimensional photonic crystal-based biosensor exhibited high sensitivity and accuracy in detecting colon cancer cells. The proposed biosensor, designed to detect colon cancer cells known as LoVo, demonstrated a sensitivity of 567 nm/RIU and a quality factor of 10615, indicating its effective performance in identifying colon cancer cells. This sensor has the potential to be used in medical applications.