The comparative evaluation of the effects of new Antihistaminic drugs (Loratadin & Claritin Rhinitis treatment

Allergic Rhinitis-chlorpheniramine-loratadineclavitin is one of the most important disease that occure commonly in east IRAN specially northeast, Khorasan. Approximately 10-15% of general population suffers from it´ s signs and symtpms. One of the best methods of allergic rhinitis treatments, that most is the most usual, is the of classic antihistaminic drugs such as: Chlorpheniramine, Pyrilamine and Diphenhydramine.These are common in the consumption of classic antihistaminics. There is more than a decade that is showed the Non Sedating Anti Histaminic Drugs are free from these side effects and do not show the CNS and anticholinergic disorders. In this clinical study, the efficacy and adverse reactions of the Loratadine and it´ s registated product calles Claritin are compared with Chlorpheniramine on 90 patients. It has been performed in northeast IRAN and the study is a kind ofdouble blind, prospective studies. 30 patients have recieved Chlorpheniramine, as the same for Loratadine and Claritin. Then the results are compared together. The results suggest than in the geographic condition of IRAN likewise, Lorataddine & specially Claritin can use as the powerful and effective nonsedating antihistamines that do not cross the blood brain barrier to show advers disorders and will be successful treatment of Allergic Rhinitis in the first line, specially in patients whom are sensitive to other antihistaminic dregs. Between them Claritin by it´ s acceptable clinical efficacy & lower side effects is preferable than Loratadine.