Efficacy of levamisol hydrochloride against alimentary tract nematodes in sheep

In the present survey the efficacy of injectable Levamisol hydrochloride was evaluated in two sheep farms in the Gilan province. In addition, 10 sheep (4 and 6 sheep as control and case respectively) were examined. Each two groups were naturally infected with lung and alimentary tract nematodes and were treated according to their individual with the dose recommended by the manufacture (1ml/ 10kg BW).The feces samples were extracted directly from the rectum of each animal and stored in labelled plastic bags. Eggs per gram (EPG) were performed for each sample by the flotation method at 0, 4, 7, 14 days post-treatment following after treatment. Fifteen days after the treatment 10 sheep were slaughtered for worm recovery and determined species of helminthes in the case and control groups for each animal. The mean of EPG were 170-350 in hospital groups and 346-390 in farm groups. The mean EPG value at 14 days posttreatment was 0-2.5 in farms group. The mean EPG value at hospital group was 0 and 430 at 14 day post- treatment in case and control groups respectively. In count and identification of adult stages after carrying out the necropsied at the 15 day post-treatment not helminth observed in the case group (6 sheep) while in controlgroup (4 sheep) had different nematodes in alimentary canal including: Haemonchus contortus (300, in two sheep), Ostertagia spp. (250, in two sheep), Trichostrongylus spp.(250, in two sheep) and lung: Dictyocaulus filaria (15, in two sheep).The results of this survey shows an efficacy of 100% for injectable levacid against adult nematodes of lung and alimentary canal in sheep.