فهرست مطالب

Jentashapir Journal of Cellular and Molecular Biology
Volume:5 Issue: 1, Feb 2014

  • تاریخ انتشار: 1392/11/04
  • تعداد عناوین: 11
|
  • Fereydoun Farrahi, Mostafa Feghhi, Farshad Ostadian, Arash Alivand Pages 429-435
    Background
    To evaluate the effect of silicone oil (SO) on bestcorrected visual acuity in phakic and pseudophakic vitrectomizied eyes.
    Material And Methods
    This prospective comparative case-control study evaluated the best-corrected visual acuity (BCVA) in SO filled vitrectomizied eyes (case group 64 eyes) compared to the vitrectomizied eyes without SO injection (control group 46 eyes). The preoperative and postoperative BCVA evaluated by Snellen chart were compared between two groups. Exclusion criteria was consist of aphakia, any degree of anterior chamber inflammation, SO bubbles in anterior chamber and increased intraocular pressure in postoperative period.
    Results
    In the silicone oil group mean ±SD preoperative log MAR of BCVA was 1.76 ± 0.60 compared to 1.82 ± 0.52 in control group (P= 0.655), and mean postoperative log MAR of BCVA was 1.68 ± 0.56 compared to 1.55 ± 0.63 in control group (P = 0.23). There were no significant differences among groups.
    Conclusion
    SO in vitreous cavity of phakic and pseudophakic eyes could change vision in some of the patients. In this study, improvement of visual outcome occurred at the end of six months in both groups and SO per se has not been found to be an attributable factor for reduction of BCVA in patients.
    Keywords: pars plana vitrectomy, silicone oil, BCVA
  • Maryam Parsanahad, Majid Karandish, Nahid Shahbazian, Mohammad Hossein Haghighizadeh Pages 437-443
    Background
    Substantial evidence indicates that diet can influence glucose homeostasis. Therefore modification of diet may have beneficial effects on diabetes risk. Limited studies have been published about the association between egg consumption and diabetes mellitus but studies about such association during pregnancy are very limited. The aim of this study was to investigate the association between egg consumption during pregnancy and risk of gestational diabetes mellitus (GDM) in Ahvaz.
    Material And Methods
    In this case - control study, 123 pregnant women with GDM and 130 healthy pregnant women were compared. Usual egg consumption during pregnancy was determined by a food frequency questionnaire. Participants were classified into three groups according to usual egg consumption, as follows: low (<1 per week), moderate (1 to less than 4 per week) and high (≥ 4 per week). Data were analyzed by logistic regression test.
    Results
    After adjustment for the possible confounding factors (age, prepregnancy body mass index, monthly weight gain, parity, abortion in previous pregnancies, macrosomia in previous pregnancies, history of GDM, diabetes or GDM in the first-degree relatives, hypertension, education and spouse''s education, gestational age) odds ratios for moderate and high egg consumption compared to low consumption were 1.602 and 1.345; (p=0.297 & p=0.573), respectively.
    Conclusion
    According to findings of this case-control study there was no association between egg consumption during pregnancy and risk of GDM.
    Keywords: diabetes, gestational diabetes mellitus, egg consumption
  • Zahra Zamanian, Hadi Daneshmandi, Fariba Khosravi Mazidi, Alireza Darabinejad, Abdollah Haghayegh Pages 445-450
    Background
    One of the valuable experiences that can be useful educational centers is using the various aspects of educational technology and recognition of importance and application training aides in learning process. This study was conducted with the objective of determination of training aids and lighting effects (video projector and white board) on the eye fatigue among students.
    Material And Methods
    In this cross-sectional study، students in health and nutrition school (Shiraz University of Medical Sciences) (n=200)، voluntarily participated (17-30 years old). A questionnaire consisted of three parts was used as data collecting tool. In the first part، demographic characteristics، in the second part، questions about specific symptoms of eye fatigue and in the third part questions related to the public eye fatigue were included.
    Results
    Results showed that between eye fatigue and the use of video projector and white board there is a significant relationship. Also، results showed that there is relationship between eye fatigue and use of glasses. According to these results، there is no significant relationship between eye fatigue with age and sex.
    Conclusion
    The results showed mean of lighting in classroom in use of video projector is lower than Iran Standard Lighting، but this parameter in use of white board taken in standard limit. Eye fatigue had association with application of video projector and using the glasses.
    Keywords: eye fatigue, training aids, students
  • Nematollah Jaafarzadeh, Nezamaddin Mengelizadeh Pages 451-459
    Background
    The release of large quantities of zinc(Zn) and nickel(Ni) into the natural environment cause some environmental problems. The aim of this research was investigation the effect of chitosan biopolymer as a natural fluctuant in order to remove Zn2+ and Ni2+ from aqueous solutions.
    Material And Methods
    Experiment in batch system as the half experiment study with change in effective parameters such as pH (6-9), dose of coagulant (10-100 mg/l), settling time and initial amount of metal was investigated.
    Results
    Results of this study showed that Zn2+ and Ni2+ removal increases with pH increases. The optimal amount of coagulant used for this study was defined between 60 - 100 mg / l respectively. So the results of this study also showed that initial concentration of metal had inverse relation with Zn and Ni removal efficiencies in coagulation and flocculation processes.
    Conclusion
    Due to chitosan properties such as biocompatibility, biodegradability, ability to remove heavy metals and also having amine, hydroxyl and carboxylic function groups it can be use as a coagulant and/or flocculant to remove heavy metals from aqueous solutions.
    Keywords: chitosan, coagulation, flocculation, zinc, nickel
  • Abdolhossein Shakurnia, Mohammad Ali Assarehzadegan, Alireza Mozaffari, Ali Khodadadi, Ghodratollah Shakerinejad, Naji Maneshdavi Pages 461-468
    Background
    Asthma is a chronic inflammatory disease of the airways which is associated with the triad of cough, wheezing and dyspnea. Different allergens can cause allergic symptoms. Identification of allergens was essential in each region for the prevention and treatment of allergic diseases. The purpose of this study was to determine sensitivity to common aeroallergens by skin prick test.
    Material And Methods
    In this cross sectional study, 111 volunteers with the sign and symptoms of allergic diseases who referred to Ahvaz Jahad-e-daneshgahi polyclinic during 2010-2011 were investigated. All patients were subjected to skin prick test with 24 common allergenic extracts. Data were analyzed by SPSS-18 software using Chi square test.
    Results
    Ninety nine patients (89.2%) had positive skin test to at least one of the aeroallergens. Common outdoor allergens (88%) were higher than indoor allergens (73%). Outdoor allergens with lots of weeds (86%) were the most common allergens. And also among the weeds, Salsola kali were the highest frequency (86.2%); and among the indoor allergen, mites were the highest frequency (40.8%). The average concentration of total serum IgE levels in patients with positive reactions was 156 IU / ml.
    Conclusion
    Weeds and mites were the most common cause of asthmatic diseases in Ahvaz. Identifying and determining the most common allergens in the region can provide the necessary recommendations to Patients took an important step in controlling and preventing disease.
    Keywords: asthma, skin prick test, allergen
  • Saeed Saeedinia, Hajieh Shahbazian, Zivar Shirinpour Pages 469-475
    Background
    The aim of this study was the evaluation of the result of two treatment methods (radioactive iodine and surgery), recurrence rate and hypothyroidism after treatment and side effects in Toxic Multi Nodular Goiter
    Material And Methods
    In this retrospective study 354 cases of toxic multi nodular toxic goiter patients that referred to endocrine clinic and treated with one of the above-mentioned treatment method were evaluated. Demographic data, thyroid examination, recurrence of hyperthyroidism, incidence of hypothyroidism after treatment and side effects of treatment were collected.
    Results
    From 326 cases, 20% were male and 80% were female. Mean age was 4814. From 326 patients treated with radioactive iodine, only 34 cases (10%) relapsed after treatment and 186 patients (57%) showed hypothyroidism after treatment.From 28 patients underwent surgery, only 2 patients (7%) had recurrence of hyperthyroidism, but hypothyroidism after surgery was seen in half of patients and in 10 patients (36%) long-term surgical complications such as laryngeal nerve damage and hyporparathyroidism were seen. Euthyroid cases without permanent side effects had not significant difference in these two treatment methods (33% in surgery versus 29% in radioactive iodine (P>0.05).
    Conclusion
    surgery in patients with TMNG does not have any advantage on radioactive iodine. Surgery can lead to lifelong complications in patient.
    Keywords: nodular goiter, hyperthyroidism, hypothyroidism, iodine therapy, thyroid surgery
  • Mohammad Shojaei, Keramatollah Rahmanian, Mohammad Moayedi, Rad Pages 477-482
    Background
    Rose angina increased the risk of coronary heart disease and death. This research was designed to determine the prevalence of Rose angina and its relationship with cardiovascular risk factors.
    Material And Methods
    In this cross-sectional study, persons with 30 years old or older were participated in Jahrom. Rose angina was assessed with Rose questionnaire. Fasting blood lipids and sugar, blood pressure, weight and height were measured. Data were analyzed by chi squared and logistic regression tests.
    Results
    The prevalence of Rose angina was 21.1%. Women had Rose angina 12.4% more than men (26.5% in women, 14.3% in men; p<0.001). Logistic regression results showed that there was an association only between obesity (OR=1.72; CI 95%:1.07-2.74) and type 2 diabetes mellitus (OR=2.19; CI 95%: 1.24-3.87) among women and Rose angina.
    Conclusion
    Rose angina was higher in women with overweight or obesity and diabetes mellitus. Therefore, regarding to the high prevalence of Rose angina should be paid more attention to cardiovascular disease and preventable risk factors seem to be necessary.
    Keywords: risk factor, rose angina, rose questionnaire, gender
  • Fatemeh Nadi Najafabadi, Akram Nazari Chegeni, Soodabeh Bassaknejad Pages 483-494
    Background
    The purpose of this study examined the relationship between negative life events and mental health with social support and resiliency mediation in female medical sciences students at Jundishapour University of Ahvaz.
    Material And Methods
    The study consisted of Ahvaz Jundishapour University, female students, among which, 188 persons were selected by random sampling. Variable measuring instruments were General Health Questionnaire (GHQ), Social Support Scale (SS-A), Connor & Davidson Resiliency questionnaire (CD-RISC) and Life Events Scale (LES).
    Results
    The results indicated that the level of resiliency and social support (p≤0/001) mediator between negative life events and mental health. Also, no relationship was found between resiliency and mental health.
    Conclusions
    Social support, negative life events and stressful events in a person''s support, reduce stress and lead to a mental health of the individual. Also, due to decrease negative emotions and increase resiliency and mental health as a resource to facilitate overcoming the stress of negative life events and eliminate the psychological effects are known.
    Keywords: resiliency, social events, negative life events, mental health
  • Hamid Reza Oreyzi Samani, Fatemeh Ahmadi Pages 495-507
    Background
    How to do the job and its design is a variable that influences the job related stress. Fatigue and job burnout are the most common side effects due to the stress at workplace. In addition, recent evidences are linked the relationship between psychological stress and exhaustion with a variety of physical symptoms and diseases like high blood pressure, elevated blood cholesterol and cardiovascular diseases. The aim of the current research was to investigate the relation between compose of job-burnout, fatigue, depression and job overload as psychological variables with cholesterol and triglyceride increments and investigate moderator role of demand-control imbalance.
    Material And Methods
    Statistical populations for this study were personal of Isfahan Gas Distributor Company in 2011. The instruments were Burnout Questionnaire of Maslach, Fatigue Questionnaire of Shirom, Overload Questionnaire of Shirom, The Epidemiologic Studies Depression Scale (CES-D) and demand control Questionnaire of Karasek. Plasma lipid was measured as dependent variable.
    Results
    Findings indicated that there were significant differences among all psychological variables (except for depersonalization) between the two appropriate and inappropriate job design groups and medical variables. It was also observed a higher level of serum lipid in the inappropriate job design group.
    Conclusion
    The high demand developed personal emotional exhaustion which in turn caused increased the blood serum lipid. However, the control on the job acted as a supportive shield preventing the individual against the developing of job burnout.
    Keywords: burnout, cardiovascular diseases, depression, fatigue, job design, lipid serum
  • Parisa Azimi Pages 509-515
    The present study developed a user-friendly computerized medical records database base on Japanese Orthopedic Association Back Pain Evaluation Questionnaire (JOABPEQ) for low back pain disorders. The JOABPEQ questionnaire contains five scales: Low back pain, lumbar function, walking ability, social life function and mental health. A computerized database called low back pain database software (LBPDS) was written with Visual C++ language software. The LBPDS is including: demographics, lumbar spinal stenosis, spondolysthesis, thoracolumbar fracture, disc herniation, chronic low back pain, morphology of the dural sac on MRI, thoracolumbar injury classification system (TLICS), and lumbar levels. The data of LBPDS stored in the Microsoft Excel, and the ability to transfer SPSS software environment would be possible. Multi-center low back pain studies would be conceivable. A total of 96 patient’s data with aged 46 ± 8 (17 to 82 years) were entered into the LBPDS and subjected to various analyses. Overall the LBPDS demonstrated acceptable reliability and validity. The LBPDS be used in departments of neurosurgery, orthopedic and physiotherapy. It seems that the low back pain database software is certified. The use of this software is recommended.
    Keywords: japanese orthopedic association back pain evaluation questionnaire, low back pain, low back pain software, low back pain database
  • Majid Reza Farrokhi, Fardin Ranjbar, Mohammad Ali Mashari, Mohammad Ardeshiri Pages 517-520
    Primary malignant sarcomas of the spine are extremely rare. Because of biological heterogeneity، these tumors have variable sensitivity to radiation and chemotherapy. Adequate local control through complete tumor removal is an important therapeutic goal. However، aggressive resection of tumors in the spinal column must be coupled with restoration of spinal column stability and minimization of neural deficits. The balance of these factors makes treatment of primary sarcomas of the spine challenging، and dictates an individual approach to treatment. We report a 17 years old lady with chief compliant of low back pain and saddle anesthesia the clinical picture and imaging characteristics were analyzed as well as the management modalities and outcome.
    Keywords: Ewing´s sarcoma, primary spine tumor