a. a. zad

Concomitant Helicobacter pylori (H. pylori) infection in patients with chronic kidney disease (CKD) may increase the risk of CKD progression. Maybe the eradication of Helicobacter pylori improves the Glomerular Filtration Rate (GFR), however, there is a challenge between studies. Therefore, this study aimed to demonstrate whether eradication of this infection improves GFR in CKD patients.

This is an interventional study on 270 CKD patients with GFR between 30 to 60 mL/min who were evaluated for H. pylori infection. A total of 79 patients were eligible for inclusion in the study. The patients underwent an early eradication treatment for H. pylori infection. The trend of changes in GFR was evaluated and compared in CKD patients in whom H. pylori infection was successfully eradicated (group A) to those whose infection had not been eradicated (group B) in a six-month follow-up period.

A total of 49 patients with chronic kidney disease (CKD) and a positive stool antigen test for H. pylori completed the study. In Group A, which received treatment for H. pylori infection, the mean glomerular filtration rate (GFR) showed an upward trend, rising from 48.54 ± 8.66 mL/min at baseline to 49.5±14.4 mL/min at six months. However, this increase was not statistically significant (P=0.18). In contrast, Group B exhibited a downward trend in GFR over the study period, decreasing from 45.77±7.92 mL/min at baseline to 45.48±14.33 mL/min at six months, with this change also not reaching statistical significance (p=0.48).

There is no significant difference in GFR between groups, however GFR in CKD patients with H. pylori infection eradication is increased.

The advancement of technology with an increasing population has led to the requirement for high-speed mobility trains. High-speed transportation by trains requires passing through soft soil conditions, which requires stability. High-speed trains are used nowadays in developed countries to reduce travel time. When the train moves at a critical speed, it can significantly increase the dynamic responses of the components on the railway lines. The present study examines the results of 3D numerical modeling, considering the impact of the high-speed train passing through the mechanical earth wall stabilized by plate anchors. Numerical modeling was carried out using Plaxis 3D finite element software. The impact of various factors such as the speed of the train (180, 200 & 250 Km/h), the number of plates (single, double, and triple), and the number of train tracks (1 & 2 tracks) have been investigated. The Hardening soil with small strain model has been used for modeling the behavior of the backfill soil. In this study, the geometrical characteristics of the Thalys high-speed train were used to model the train passing through the walls of 6 meters that were stabilized with plate anchors. From the results, it was concluded that Increasing train speed from 160 to 250 Km/h increases the settlement under the rails by 11% and increases the horizontal displacement of the wall by 13%. It was confirmed that increasing train speed will result in an increase in the settlement under the rails and increases the horizontal displacement of the wall in all investigated cases. Increasing the number of plates along with decreasing their dimensions has a positive effect on the wall’s performance with regard to the horizontal displacement of the wall. Also, it should be mentioned that by increasing the number of train tracks from 1 to 2, the settlement under the rails increased by 5%, and the horizontal displacement of the wall increased by 20%.

Saliva is one of the most important body fluids. The lack of this fluid has many outcomes for the patient. The aim of the present study was to detect objective and subjective dry mouth in individuals with no oro-dental complications in Shiraz, Iran and compare these factors to depression level, medication intake and level of education. 

In the present descriptive cross-sectional study conducted at Shiraz Dental School in 2018, 450 samples were selected from the Patients' companions referred to Shiraz Dental School over 18 years. In the present study, the Fox questionnaire was used to mentally assess dry mouth (zerostomia) and the Zong self-assessment scale was used to assess depression. Spitting method was used to evaluate the amount of stimulated and unstimulated saliva (objective dry mouth or hyposalivation). When saliva was less than 0.1 g/min, objective dry mouth was stimulated and when saliva was less than 0.7g/min, objective dry mouth was considered non-irritating. Data were analyzed using SPSS software and chi-square test.

In the present study, 399 patients (118 males, 280 females) were studied. Dry mouth (zerostomia) was found in 46% of the population. However, 18.5% had non-stimulated objective dry mouth and 12.3% had objectively stimulated dry mouth. Patients aged 30 to 45 years suffered more from mental and objective dry mouth compared to other age groups (p=0.048 and p=0.032). Depression, use of antihypertensive and antidiabetic drugs and low level of education were significantly associated with objective dry mouth (p<0.01, p<0.01 and p=0.038).

Mental dry mouth can occur apart from objective dry mouth. Correspondingly, dry mouth as an objective and mental symptom can be seen not only in the elderly but similarly in the young peoples. Physicians and dentists must deal with the factors that cause this complication, such as; depression, medications, and education levels as a disabling and destructive condition that affects all age groups.

Patients with chronic liver failure (CLF) faced serious medical conditions including the oral cavity.

To investigate the prevalence of oral mucosal lesions, saliva flow rate, and dental complications in candidates of liver transplant surgery.

In this cross-sectional study, oral and dental health of 77 patients with CLF and 77 healthy individuals were assessed for oral mucosal lesions, salivation rate, DMFT (decayed, missing, filled teeth) index, and bone level. To carefully determine the indices and examine the patients thoroughly, a panoramic radiography was also taken from each participant.

The frequency of oral mucosal lesions in patients was significantly (p<0.001) higher than the comparison group. The most frequent lesion identified was angular cheilitis followed by candidiasis. The mean saliva flow rate in the patients (0.85 g/min) was also significantly (p<0.001) lesser than that in healthy individuals (1.58 g/min). The DMFT index and bone level were not significantly different between the two groups. Nor was a correlation between the MELD score and each of DMFT index, bone loss, or oral mucosal lesions.

Mucosal lesions, especially fungal-related lesions, are more prevalent in the oral cavity of patients with CLF. The saliva production rate is reduced due to various medications used in this group. Patients with CLF are prone to oral infections and a thorough oro-dental examination is crucial in this group of patients. Vigorous oral hygiene instructions should be offered to liver cirrhosis individuals.

Conventional rehabilitation in stroke patients is more likely to use repetitive movements to improve motor function, which may be difficult for people with motor limitations. Mental imagery training can be done without moving the affected limbs, and this method is safe, cheap and accessible. The aim of this study is to investigate the effect of motor imagery training with sensory feedback on sensory-motor function of the upper extremity in patients with chronic stroke. In this non-randomized clinical trial, 30 stroke patients with level of upper extremity function according to Brunnsrom’s recovery ≥ 2, and cognitive function level according to MMSE ≥ 21 were selected through non-probability sampling from rehabilitation centers and randomly divided into intervention and control groups. Patients in the control group received conventional rehabilitation programs, and patients in the intervention group received motor imagery training with sensory feedback in 12 sessions (45 – 60 minutes), in addition to conventional rehabilitation programs. Before and after the interventions, sensory and motor functions were assessed using Box-Block test, Purde-Pegbord test, range of motion, FMA-UE total and FMA-UE coordination/speed, 2-point-discrimination, Nottingham-Sensory Assessment, Modified-Ashworth Scale and Stroke Impact Scale. FINDINGS: Mean percentage of changes in motor function and speed/coordination of upper extremity, shoulder and elbow range of motion and gross dexterity was higher in the interventional group (50%, 50%, 80%, 50% and 80%, respectively) compared with the conventional rehabilitation group (20%, 18%, 50%, 30% and 30%, respectively) (p≤0.05). However, both interventions had similar effect on sensory function, fine dexterity, muscle tone and activities of daily living. The results of the study showed that motor imagery training with sensory feedback along with conventional rehabilitation could enhance the motor function, gross dexterity and range of motion of the upper extremity in chronic stroke patients.

Let $G$ be a non-abelian group. The non-commuting graph $Gamma_G$ of $G$ is defined as the graph whose vertex set is the non-central elements of $G$ and two vertices are joined if and only if they do not commute.In this paper we study some properties of $Gamma_G$ and introduce $n$-regular $AC$-groups. Also we then obtain a formula for Szeged index of $Gamma_G$ in terms of $n$, $|Z(G)|$ and $|G|$. Moreover, we determine eccentric connectivity index of $Gamma_G$ for every non-abelian finite group $G$ in terms of the number of conjugacy classes $k(G)$ and the size of the group $G$.