amirpouya tanhaei

One of the secondary consequences of burnout is a significant reduction in cognitive functions, the most obvious and important of which is the cognitive function of attention and control, which can play a vital role in efficiency and prevention of errors at work in many occupations. On the other hand, a neurological examination is needed to understand better the relationship between burnout and its consequent depressive disorder regarding the cognitive function of the attention network of these individuals. Depressed people usually have neuropsychological disorders. Therefore, the present study aimed to investigate the cognitive performance of executive control of health care workers with shift jobs on the verge of burnout using the Attention Network Test (ANT) Event-Related Potential (ERP).

The sample included 26 health care providers on the verge of burnout in Rasoul Akram Hospital in Tehran (15 without depression and 11 with mild to moderate depression) selected by purposive sampling. The rate of burnout was assessed by the Maslach Scales (1981); depression was evaluated by the Depression, Anxiety and Stress Scale-21 (DASS-21); attention was assessed by the Network Attention Test (ANT) and simultaneously with the behavioral test. We investigated the event-related potential (ERP) indicators of attention processing. Independent t-test and paired t-test were used for data analysis.

The results of behavioral performance revealed no significant difference between the two groups in the three attention networks; however, Significant differences can be seen in ERP brain waves related to the executive function of attention, especially by increasing the SP wave and N2 wave component compared to normal individuals without depression

: Significant differences can be seen in ERP brain waves related to the executive function of attention, especially by increasing the SP wave and N2 wave component compared to normal individuals without depression. According to the study results, it can be stated that to improve cognitive performance in people's work environments, measures should be taken to reduce burnout and depression, and employees should perform their activities with better performance and help the quality growth of the work environment.

For centuries, spices have been consumed as food additives or medicinal agents. However, there is increasing evidence indicating the plant‑based foods in regular diet may lower the risk of neurodegenerative diseases including Alzheimer disease. Spices, as one of the most commonly used plant‑based food additives may provide more than just flavors, but as agents that may prevent or even halt neurodegenerative processes associated with aging. In this article, we review the role and application of five commonly used dietary spices including saffron turmeric, pepper family, zingiber, and cinnamon. Besides suppressing inflammatory pathways, these spices may act as antioxidant and inhibit acetyl cholinesterase and amyloid β aggregation. We summarized how spice‑derived nutraceuticals mediate such different effects and what their molecular targets might be. Finally, some directions for future research are briefly discussed.

The complexity of multiple sclerosis (MS) and the incompetence of a large number of promised treatments for MS urge us to plan new and more effective therapeutic approaches that aim to suppress ongoing autoimmune responses and induction of local endogenous regeneration. Emerging data propose that hematopoietic, mesenchymal, and neural stem cells have the potential to restore self‑tolerance, provide in situ immunomodulation and neuroprotection, as well as promote regeneration. Thus, in this article, we will first provide an overview of the cell sources for proposed mechanisms that contribute to the beneficial effects of stem cell transplantation, the ideal route and/or timing of stem cell‑based therapies for each main stem cell group, and finally, an overview of the current status of stem cell research in clinical trial stages in MS by comparable and healthy therapeutic effects of different stem cell therapies for MS patients.

Vitamin D insufficiency and serum calcium disturbance have been reported to be more common in Parkinson’s disease (PD) patients than in healthy control subjects, which may be due to a chronic disease or reduced mobility contributes to these relatively disturbances. Because of the high-vitamin D insufficiency in our population, we aimed to compare a biochemical levels which are related to bone metabolism, in PD patients in comparison with age-matched healthy controls, for the 1st time in a Middle East population. This case-control study was involved 105 (20 were excluded) PD patients, who were age- and -sex matched with 112 controls. 25-hydroxyvitamin D (25OHD) and parathyroid hormone analyzed by enzyme immunoassay; another laboratory data including, calcium, phosphorous, and alkaline phosphatase were performed by spectrophotometric methods. There was no significant difference in 25OHD between PD patients and control group (P = 0.071). 25OHD level was not significantly different in PD patients compared to controls {odds ratio 1.003, (confidence interval [CI], 0.98-1.02), P value 0.793}. None of the other biochemical levels did not induce more chance for PD, only we observed in men has more risk of PD than women (odds ratio 2.53, [CI, 1.27-5.03], P value 0.008). Our data do not support a possible role of vitamin D insufficiency in PD. Regarding to variable changes in biochemical markers in PD patients than in controls; further studies are suggested to determine any plausibility role of them as a causal relationship or as an outcome of PD.