c. zhang

The vibration of water injection pipeline systems in oilfields creates challenges in terms of safe long-term operation. To fully understand the vibration mechanism of plunger-powered high-pressure water injection pipelines, we conducted fluid pressure pulsation calculations and fluid structure coupling modal evaluations using finite element analysis software to study the effects of pressure, pipe length, and pipe clamp on the vibrations. The results indicate that the total displacement increases with increasing pressure, although the magnitude of the increment gradually decreases. The pipe length has a significant impact on the natural frequency. Based on the findings of the present study, we proposed that pipe clamps could be introduced to reduce the vibrations in an existing high-pressure plunger pump water injection pipeline, and the overall design was optimized. Comparative modal analysis revealed the most practical number and position of the pipe clamps to be suitable for a pressure range of 42–70 MPa.

To explore the diagnosis and evaluation efficacy of liver iron concentration (LIC) based on magnetic resonance quantitative technique in liver iron overload in patients with long-term transfusion.

From November 2021 to January 2023, 30 chronic aplastic anemia (CAA) patients with long-term blood transfusion admitted to our hospital were included as the study group. Simultaneously, 20 healthy volunteers with matched gender and age were included in the control group. The serum ferritin (SF), serum iron, total iron binding capacity and transferrin saturation (TSAT) between the two groups was calculated and compared. LIC was evaluated using Liver Magnetic resonance imaging (MRI)-T2* map imaging. The correlation between LIC and SF and TSAT was analyzed, and the diagnosis value of LIC in hepatic iron overload was calculated. Low-risk patients (n=22) diagnosed with iron overload received continuous regular iron removal treatment and the SF, TSAT and LIC were measured after 6 months.

SF, TSAT and LIC were higher in CAA patients relative to the healthy controls (P<0.05). LIC was positively correlated with SF (r=0.74, P<0.001) and TSAT (r=0.67, P<0.001). The sensitivity and specificity of LIC in the diagnosis of hepatic iron overload were 80.00% and 100% based on SF, and 76.0% and 100% based on TSAT, respectively. Additionally, SF, TSAT and LIC were all declined after 6 months of treatment (P<0.05).

The detection of LIC based on MRI-T2* is an effective and non-invasive means for the assessment of liver iron load in patients with long-term transfusion.

Unsteady numerical simulation of single passage was carried out on NASA Rotor 35 to study the influence of the radial inclined angle of self-circulation casing treatment (SCT) on the performance and stability of a transonic compressor at 100% design speed. The radial inclined angles were set to 0°(D0), °(D30) and 60°(D60), respectively. The calculated result indicates an increase in the stall margin improvement (SMI) and the design efficiency improvement (DEI) as the radial inclined angle increases gradually. The SMI of the SCT with a 60° radial inclined angle is 12.5%, the biggest among the three SCTs, and the peak efficiency improvements (PEI) of the SCTs are almost the same. The radial inclined angle is provided with the effect of strengthening the self-circulation casing treatment effect, which further improves the stable working range of the compressor, and the efficiency loss is also lower than that of the 0° angle structure. The flow conditions inside the bleeding part can be improved by radially skewing the self-circulating structure toward the rotor rotating direction.

Epithelioid sarcoma (ES) is a rare soft tissue tumor that mainly occurs under the skin of the extremities. ES in the groin area may be easily misdiagnosed with undifferentiated pleomorphic sarcoma, leiomyosarcoma, rhabdomyosarcoma, and other mesenchymal tumors. Herein, we reported a single case of a patient with proximal-type epithelioid sarcoma of the groin, including its clinical and imaging findings. We also discussed some previously reported similar cases.

Our ES patient was a 24-year-old male who developed a subcutaneous nodule in the groin area 1 year before admission. After careful clinical and pathological examination, the patient was diagnosed with ES. He received chemotherapy (doxorubicin, ifosfamide plus cisplatin) and, later on, surgery. His symptoms improved, and he is still being followed up. In addition, we conducted a review of the literature and compared our data with 12 previously reported similar cases (including 17 patients with ES involving the groin).

ES is a highly invasive tumor prone to metastasis and postoperative recurrence. Surgery seems to be the most effective treatment for ES. The effectiveness of auxiliary and radiotherapy needs to be confirmed by a large amount of data. A systematic understanding of the clinical and imaging features of ES in the groin area may help clinical and imaging doctors to correctly diagnose the disease.

To evaluate structural variation of the parotid gland in post-radiotherapy oral carcinoma patients.

52 patients (33 males, 19 females) with histologically confirmed cancer of head and neck region were enrolled. All the patients underwent intensity modulated radiotherapy (IMRT) with linear accelerator. A quantitative analysis was conducted with the help of contrast enhanced computed tomography (CECT) scan regarding the changes in the volume and density of the parotid glands (PGs) along with the assessment of their interrelationship in relation to the mean dose applied to the glands. The evaluations were done immediately after radiotherapy, and after 2 and 3 years.

Parotid size reduction was observed in 77.77 % of cases immediately after radiotherapy with a mean dose of 26.66 Gy applied to the parotid glands. Parotid shrinkage reduced to 61.5 % cases three years post radiotherapy. High density changes were revealed by 69.2 % cases immediately after radiotherapy with a mean dose of 34.53 Gy applied to these parotid glands. Low density changes were revealed by 48.1 % cases after 2 years follow up which further reduced to 25 % at three years follow up.

There was evidence of structural variation in the PGs during the course of IMRT which was significantly related with the mean dose applied to them. There were high density changes and low density changes immediately after radiotherapy and 2-3 years post-radiotherapy respectively. Further there was volumetric shrinkage post-radiotherapy which shows recovery 2 and 3 years post-radiotherapy.

To observe the efficacy of temozolomide in combination with radiotherapy against metastatic brain tumors.

This study was a prospective, observational, open-label study, conducted in clinical practice implanted for metastatic brain tumor patients. A total of 106 patients with metastatic brain tumors were enrolled in this study, and according to the sequence of admission, they were randomized into the experiment group (temozolomide + radiotherapy) and the control group (radiotherapy). During the 24 months of follow-up, we compared the clinical efficacy, recurrence time, survival time and quality, and the adverse reactions of the patients between two groups.

Short-term remission after treatment was higher in the experimental group compared to control (P<0.05). During the 24-month follow-up, we found that patients in the experiment group had longer recurrence time and survival time than their counterparts in the control group (P < 0.05). After treatment, the scores of the life quality of patients in the experiment group were better than those in the control group (P<0.05). Also, there was a lower rate of the incidence of the adverse reactions in the experiment group (P<0.05).

For metastatic brain tumors, temozolomide in combination with radiotherapy works better as a safe and reliable strategy in prolonging the survival time, increasing life quality while reducing the adverse reactions. The strength of this study was evaluating the quality of life as an important outcome of the chemotherapy+radiotherapy regimen.

Market demand mostly possibly affected by the seller’s credit in many industrial practice, this study aims to investigate the beneficial performance of the supply chain considering the credit-linked demand under three different circumstance. We firstly develop a demand model which is a function of the trade credit period. Moreover, the supplier determines optimal trade credit period and the retailer determines optimal replenishment cycle time. Under these conditions, we first present optimal solutions for the centralized decision and the decentralized decision in Stackelberg models. Then, we develop a set of theorems to determine the optimal results. Finally, we provide a numerical example and sensitivity analysis to illustrate the efficiency of the proposed models and optimal solutions. The finding reveals that the trade credit period, replenishment cycle time, retailer’s profit, supplier’s profit and profit of the supply chain are strongly influenced by ordering cost, retail price, production cost, holding cost and the interest rate. In addition, we also find that under the condition of the trade credit, the supply chain that the supplier dominated has a better performance than that the retailer dominated. While when the supplier don’t provide the trade credit period, the result is the opposite.

This paper analyzes the effects of structures and loads on the static bending and free vibration problems of bilayer beams. Based on static mechanical equilibrium and energy equilibrium, the static and dynamic governing equations of bilayer beam are established. It is found that the value of the thickness ratio has a significant effect on the static and dynamic responses of the beam, and the structure factors have their own critical value. When the value of the relative thickness is lower than its critical value or the length thickness ratio is greater than its critical value, the static and dynamic responses of the beam increase obviously. The results reveal that a critical value exists in bilayer beam, the value has noticeable influence on the mechanical properties of bilayer beams. Therefore, investigators should predict the critical structures accurately, when they design the bilayer beam.

As the diploid progenitor of common wheat, Aegilops tauschii is used as a genetic resource for improving common wheat. In this study, the genetic differentiation index between Yellow River (Shaanxi and Henan) and Xinjiang groups (0.322, 0.377) were obviously higher than between the former and Central Asia groups (0.231, 0.289). Meanwhile, the genetic distances between Yellow River (Shaanxi and Henan) and Xinjiang groups (0.285, 0.329) exhibit larger values compared with those between the former and Central Asia groups (0.283, 0.321). These results reveal that the genetic constitution of Yellow River and Central Asia groups is of more similarity compared with Xinjiang group. The phylogenetic tree demonstrates that Ae. tauschii in Yellow River and part of that in Central Asia are firstly gathered to be a subset. Then the subset and Xinjiang group are classified into a clade, which could be assigned to Central Asia and Middle East populations, implying that Ae. tauschii in Yellow River has a closer relationship with part of that in Central Asia compared with Xinjiang. Our finding further clarifies that Ae. tauschii in Yellow River might be directly derived from one/several types from Central Asia such as Turkmenistan, Pakistan, and Afghanistan.