d. zhang

Multimodal medical imaging plays a key role in the diagnosis and differential diagnosis of myocarditis, enabling a comprehensive assessment of cardiac structure and function.

We used multimodal medical imaging technology to diagnose and differential diagnose patients with myocarditis, and analyzed the patient data in detail.

Multimodal medical imaging techniques provide a wealth of information to help distinguish myocarditis from other heart diseases.

Multimodal medical imaging is of great value in the diagnosis and differential diagnosis of myocarditis, but there are still some challenges and limitations in its application.

Oil spill accidents in damaged submarine-buried pipelines cause tremendous economic losses and serious environmental pollution. The accurate prediction of oil spills from subsea pipelines is important for emergency response. In this study, the volume-of-fluid model, realizable k–ε turbulence model, and porous-medium model were employed to describe the process of an oil spill from a submarine pipeline to the sea surface. The effects of seawater density, seawater velocity, and pipeline buried depth on the transverse diffusion distance of crude oil and the time at which crude oil reaches the sea surface were obtained through numerical calculations. The calculation results show that, with a decrease in seawater density and an increase in seawater velocity and pipeline depth, the diffusion rate of crude oil decreases significantly, the maximum transverse diffusion distance increases and crude oil takes a long time to reach the sea surface. In particular, compared with a sea density of 1045 kg/m3, the transverse distance of a sea density of 1025 kg/m3 is increased by 0.091 m. When the seawater velocity is greater than 1.5 m/s, the diffusion of crude oil in seawater is significantly affected, the seawater velocity increases to 0.35 m/s, and the transverse diffusion distance of oil to the sea surface increases to 12.693 m. When the buried depth of the pipeline reaches 0.7 and 1.3 m compared to 0.1 m, the diffusion widths of crude oil in sea mud rise by 20% and 32.5%, respectively. The time required for crude oil to reach the sea surface and the transverse diffusion distance of crude oil migrating to the sea surface were analyzed using multiple regression, and the fitting formulas were obtained. The results provide theoretical support for accurately predicting the leakage range of submarine-buried pipelines and provide valuable guidance for submarine-buried pipeline leakage accident treatment schemes.

To investigate the use of uniportal video-assisted thoracoscopic surgery (U-VATS) in the treatment of non-small cell lung cancer (NSCLC).

A total of 82 patients with early NSCLC in our hospital from May 2019 to January 2021 were enrolled to this study. Forty-one patients treated with spontaneous breathing U-VATS were the research group (RG), and 41 with conventional thoracoscopy were the control group (CG). Fasting peripheral blood was drawn from patients before (T0), one (T1) and three days after surgery (T2), respectively. White blood cells (WBC), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), matrix metalloproteinase-9 (MMP-9) and T-lymphocyte subsets were measured in the blood. In addition, we counted the conversion rate to open chest and tracheal intubation in the RG, and compared the operation time, intraoperative bleeding, chest drainage, chest tube retention time, antibiotic application time, postoperative hospital stays and complications between groups. Finally, a 1-year prognostic follow-up was performed to record overall survival, chemotherapy rate, and recurrent metastasis rate.

At T1, WBC, IL-6, TNF-α, and MMP-9 were lower in the RG than in the CG, while immune function was better in the RG at T1 and T2 (P<0.05). Complication rates were lower in the RG than in the CG when compared (P>0.05). The prognosis of 1-year overall survival, chemotherapy rate, and recurrence rate were not different between the two groups (P>0.05).

Spontaneous breathing U-VATS can effectively reduce the inflammation and enhance the stability of immune function in NSCLC patients undergoing surgery.

Ultraviolet radiation is the main cause of photoaging, which can induce oxidative stress and cellular senescence in the skin. It has been demonstrated that platelet-rich plasma (PRP) can significantly improve skin photoaging. However, the mechanism by which PRP improves photoaging remains unclear.

In this study, UVA-induced SD rats were used as a skin photoaging model and administered with PRP treatment, aiming to elucidate the potential mechanism of its protection against photoaging.

They showed that PRP injection on the back of rats improved skin photoaging, oxidative stress, and inflammation, and inhibited skin cell apoptosis. In addition, RPR activated autophagy to inhibit NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome signaling pathway-related proteins.

Our experimental results suggest that PRP plays an anti-UVA photoaging role by inhibiting autophagy and NLRP3 signaling pathways. Our study is the first to suggest that PRP anti-skin photoaging is associated with autophagy and NLRP3, providing a potential therapeutic approach for skin photoaging.

To investigate the clinical efficacy of apatinib in combination with oxaliplatin + 5-fluorouracil + leucovorin in clinical chemotherapy for the advanced gastric cancer.

Between June 2016 and December 2018, we enrolled a total of 92 patients with advanced gastric cancer who were receiving 4500 cGy of radiation through the 5 weeks after resection of adenocarcinoma, and divided them into two groups as per the treatment strategies, with 46 patients in each group. Patients in the control group underwent the regular chemotherapy (oxaliplatin + 5-fluorouracil + leucovorin), while those in the observation group would additionally receive the medication of apatinib. We compared the efficacy, changes in the levels of high-sensitivity C-reactive protein (hs-CRP) and Tumor necrosis factor (TNF-α) in serum, prognosis and adverse reactions between two groups, or before and after treatment.

In the observation group, the total effectiveness rate was higher than that in the control group. Also, after treatment, significant decreases were found in levels of high-sensitivity C-reactive protein and TNF-α in serum of patients in the observation group, more evident than those in the control group. Moreover, progression-free survival and total survival durations of patients were significantly longer than those in the control group, while the incidence rate of adverse reaction was reduced sharply (all P < 0.05).

our study showed that apatinib combination with oxaliplatin + 5-fluorouracil + leucovorin seems to have promising efficacy, and is worthy of being studied as a new regimen of gastric cancer treatment.

To observe the efficacy of temozolomide in combination with radiotherapy against metastatic brain tumors.

This study was a prospective, observational, open-label study, conducted in clinical practice implanted for metastatic brain tumor patients. A total of 106 patients with metastatic brain tumors were enrolled in this study, and according to the sequence of admission, they were randomized into the experiment group (temozolomide + radiotherapy) and the control group (radiotherapy). During the 24 months of follow-up, we compared the clinical efficacy, recurrence time, survival time and quality, and the adverse reactions of the patients between two groups.

Short-term remission after treatment was higher in the experimental group compared to control (P<0.05). During the 24-month follow-up, we found that patients in the experiment group had longer recurrence time and survival time than their counterparts in the control group (P < 0.05). After treatment, the scores of the life quality of patients in the experiment group were better than those in the control group (P<0.05). Also, there was a lower rate of the incidence of the adverse reactions in the experiment group (P<0.05).

For metastatic brain tumors, temozolomide in combination with radiotherapy works better as a safe and reliable strategy in prolonging the survival time, increasing life quality while reducing the adverse reactions. The strength of this study was evaluating the quality of life as an important outcome of the chemotherapy+radiotherapy regimen.

In this paper, we introduce a general$(oplus,otimes)$-convex function based on semirings $([a,b],oplus, otimes)$ with pseudo-addition $oplus$ andpseudo-multiplication $otimes.$ The generalization of the finiteJensen's inequality, as well as pseudo-integral with respect to$(oplus,otimes)$-convex functions, is obtained. This also generalizes Jensen's inequalities for Lebesgue integral and the results of Pap and v{S}trboja cite{12}. Meanwhile, we also prove Jensen's inequalities for pseudo-integrals on semirings $([a,b], sup, otimes)$with respect to nondecreasing functions and present correspondingresults for generalized fuzzy integrals.

As the diploid progenitor of common wheat, Aegilops tauschii is used as a genetic resource for improving common wheat. In this study, the genetic differentiation index between Yellow River (Shaanxi and Henan) and Xinjiang groups (0.322, 0.377) were obviously higher than between the former and Central Asia groups (0.231, 0.289). Meanwhile, the genetic distances between Yellow River (Shaanxi and Henan) and Xinjiang groups (0.285, 0.329) exhibit larger values compared with those between the former and Central Asia groups (0.283, 0.321). These results reveal that the genetic constitution of Yellow River and Central Asia groups is of more similarity compared with Xinjiang group. The phylogenetic tree demonstrates that Ae. tauschii in Yellow River and part of that in Central Asia are firstly gathered to be a subset. Then the subset and Xinjiang group are classified into a clade, which could be assigned to Central Asia and Middle East populations, implying that Ae. tauschii in Yellow River has a closer relationship with part of that in Central Asia compared with Xinjiang. Our finding further clarifies that Ae. tauschii in Yellow River might be directly derived from one/several types from Central Asia such as Turkmenistan, Pakistan, and Afghanistan.