جستجوی مقالات مرتبط با کلیدواژه « anxiety » در نشریات گروه « پزشکی »

The age of laboratory animals is an important variable at the time of the experiment. GABA is a neurotransmitter that is synthesized from the amino acid glutamate by the enzyme glutamate decarboxylase (GAD). GAD67 is the main enzyme responsible for the production of GABA and its reduction causes a decrease in GABA levels. Since the prefrontal cortex is one of the important brain structures in the neuronal circuits of anxiety and there has not been a comprehensive study related to anxiety and the change in gene expression of this enzyme in the prefrontal cortex at different ages, in this study, with the help of the elevated plus maze device, this assay was investigated.

Rats with three age groups of 21, 42 and 360 days were used. At each age, the grouping of animals was as follows: 1) control group, 2) innate anxiety group in which the rats were placed in the elevated maze test, 3) diazepam administration group + innate anxiety group. Immediately after the test, the medial prefrontal cortex of the animals was isolated and evaluated with the help of a real time PCR technique.

Our results showed that anxiety in 21-day-old mice were higher than other ages. GAD67 enzyme expression of the prefrontal cortex did not change in innate anxiety and age had no effect on it (p > 0.05).

It seems that in the prefrontal cortex, other components of the GABAergic system or other neurotransmitters such as serotonin, norepinephrine, etc. and their related mechanisms are involved in innate anxiety.

The respiratory disease Covid-19 was first detected in Wuhan, China and spread as a pandemic. The mental vulnerability of nursing students to the stress caused by professional challenges, especially during the corona virus pandemic, was one of the problems that had to be addressed. The purpose of this study is to investigate depression, anxiety and stress in nursing students of Tehran Islamic Azad University of Medical Sciences during the corona virus pandemic in 2021.

This research is a cross-sectional descriptive study that was conducted in the secend half of 2021 in the nursing faculty of Tehran Islamic Azad University of Medical Sciences among 108 nursing students. The data collection tool includes two parts of the demographic characteristic's questionnaire as well as the DASS-21 depression, anxiety and stress scale, which was provided to the students as an online questionnaire. For data analysis, SPSS software version 16 was used for descriptive statistics and chi-square test, and a significance level of less than 0.05 was considered.

Based on DASS-21, the average stress intensity of the participants was 8.40 ± 0.5, the average depression intensity of the participants was 6.41 ± 0.51, and the average anxiety intensity of the participants was 5.48 ± 0.41. There was no significant relationship between the background variables of age, gender, marriage and hospital employment with the level of depression, anxiety and stress of the students participating in the research.

According to the obtained results, the stress subscale had the highest intensity and the anxiety subscale had the lowest intensity among the participants. It seems that nationwide vaccination against covid-19 disease and paying attention to training nursing students to face similar critical cases and increasing personal protective equipment during the pandemic can be effective in preventing nursing students from depression, stress and anxiety.

More than 1 million colorectal cancers (CRC) are diagnosed annually. This cancer is the cause of 600,000 deaths, and many of these deaths can be reduced by screening. Colonoscopy is the best screening method and tool to diagnose CRC, but it causes anxiety and worry in patients. In addition, no appropriate tool has so far been introduced for assessing anxiety in these patients. Accordingly, the present study aimed to design and psychometrically evaluate a tool for assessing anxiety in patients undergoing colonoscopy.

This methodological study used a descriptive-cross-sectional approach to design a psychometric questionnaire. To this end, 106 patients participated in this research, and the questionnaire was completed online. The validity of the list and the analysis of its main components were determined through exploratory factor analysis with varimax rotation and confirmatory factor analysis. The reliability of the tool was also checked with Cronbach’s alpha.

Overall, 20 terms of the questionnaire were examined by exploratory analysis, and 5 factors explained 57.76% of the total variance. The internal consistency of the tool with Cronbach’s alpha was 0.91.

The findings of the research revealed that the tool for assessing anxiety in patients undergoing colonoscopy with 20 items and 5 factors has adequate validity and reliability and can be used to assess the anxiety of colonoscopy patients.

The results of this research can change policies in the field of treatment to reduce the anxiety of colonoscopy patients.

Accompanying sleep disorders such as insomnia, delayed sleep, and wakefulness, as well as anxiety and depression with obsessive-compulsive disorder, are common in patients with OCD. However, not much research has been done on the relationship between sleep disorders and the severity of symptoms in patients with OCD. This article examines the frequency and relationship between sleep disorders, depression, anxiety, and the severity of obsessive-compulsive symptoms in patients with OCD.

Convenience sampling was used in this cross-sectional research. The participants in the study were those who were referred to the clinic of a psychiatric hospital and the central clinic complex in Sari. Obsessive-compulsive disorder diagnosis of the participants was confirmed by a psychiatrist based on DSM-5 diagnostic criteria. Eighty-eight patients participated in the study after obtaining informed consent. Demographic questionnaires, Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), morning-evening questionnaire (MEQ), Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), WHO-5 well-being (Depression) Index, and Generalized Anxiety Disorder-7 (GAD-7). Data analysis was done with SPSS version 20 software.

Out of 88 patients, 65 (73.86%) were women 23 (26.14%) were men, 71.59% were married, 57.95% had under diploma degree, and 94.22% had no history of drug use. The average age of the patients was 44.48 ± 11.51 years. The duration of OCD was 11.28±14.60 years In terms of the severity of OCD symptoms, 1.1% was very mild, 19.32% was relatively mild, 42.45% was moderate, and 37.50% was severe. In the type of sleep schedule, 17.03% were inclined to evening or relative evening type. Four patients (4.62%) had daytime sleepiness. Also, 52 patients (61.90%) had some degree of insomnia. In terms of the severity of insomnia, 23.86% were mild, 28.40% were moderate and 6.81% were severe. The frequency of depression was 68% and anxiety was 79%. No statistically significant relationship was found between the severity of obsessive-compulsive disorder and hypersomnia, evening chronotype, anxiety, and depression. But insomnia (P= 0.046) and duration of illness (P= 0.004) were related to it. The Pearson correlation coefficient between age, duration of obsessive-compulsive disorder, and severity of obsessive-compulsive symptoms was 0.169 (P= 0.116) and 0.377 (P=0.001), respectively. Spearman's correlation coefficient between the severity of obsessive-compulsive symptoms with depression and anxiety was 0.090 (P=0.403) and 0.044 (P=0.685), respectively. The average severity of obsessive-compulsive symptoms was 23.48±7.87 in women and 20.04±5.88 in men, and no significant difference was seen in both sexes (P=0.060). In linear regression, the two factors affecting the severity of obsessive-compulsive symptoms were the duration of the illness and the severity of insomnia.

Considering the higher frequency of insomnia in patients with obsessive-compulsive disorder compared to the normal population and its role in the severity of obsessive-compulsive disorder symptoms, it is necessary to examine patients with obsessive-compulsive disorder in terms of insomnia. Also, older OCD patients should be examined more carefully in terms of the severity of obsessive-compulsive symptoms.

 Since the past, the use of medicinal plants in the treatment of many diseases has attracted people's attention. The outbreak of the Covid-19 disease since December 2019 may have led to stress and anxiety due to its unknown nature. The present study aims to investigat the recognition, amount of consumption, source of preparation and effectiveness of sedative medicinal plants in reducing stress caused by the spread of this disease from the perspective of the people of Khouzestan, Isfahan, Markazi and Chaharmahal and Bakhtiari provinces.

 The present research is an applied cross-sectional-analytical type that was conducted at one point in time (Spring 2019). The research tool was a researcher-made online questionnaire with 10 general items, 23 specialized items and 12 items regarding the names of commonly used plants. Questionnaires were randomly distributed in four selected provinces. Data was analysed by SPSS 22 software.

Ethical Considerations:

 In this study, criteria concerned with moral principles as confidentiality, personal satisfaction and freedom of participants in cooperation or non-cooperation during the study process have been observed.

The findings of one-sample t-test showed that the most effective factor in the use of sedative medicinal plants was the preference for the use and therir effectiveness compared to chemical drugs. The results showed that the residence province had a significant effect on the item"sedative medicinal plants had a significant effect in reducing the stress of the corona crisis in me" and the people of the Markazi province had the highest average. Ginger (3.61), thyme (3.43) and cinnamon (3.42) were the most consumed herbs among the people, which seems that in addition to the goal of reducing anxiety, increasing the immune system was also one of the reasons for using them which is also consistent to the results of t -test. Also, the findings showed that people considered Attari as the main source of supply.

 People in different provinces had different knowledge of sedative plants and used them to reduce the stress of this disease.

The spread of COVID-19 pandemic caused anxiety in the medical staff, especially nurses, which contributed to many physical and mental problems in them. The relationship between cognitive flexibility and COVID-19-related anxiety is still unknown. This study aims to measure the relationship between cognitive flexibility and COVID-19-related anxiety in nurses, and find the related factors.

This is a descriptive-analytical study with a cross-sectional design that was conducted in 2021 on 120 male and female nurses working in one of the hospitals affiliated to Arak University of Medical Sciences. Sampling was done using a stratified and random sampling method for three months. The cognitive flexibility inventory (CFI) and the corona disease anxiety scale (CDAS) were employed to collect data. Data analysis was performed in SPSS software, version 23, using independent t-test, analysis of variance (ANOVA) , and Pearson correlation test.

The mean total score of CDAS was 21.09±3.96, ranged from 12 to 32. The mean total score of CFI was 52.78±9.97, ranged from 30 to 81. Based on Pearson’s correlation test results, there was no significant relationship between cognitive flexibility and COVID-19-related anxiety (p>0.05). The mean scores of CFI and CDAS were not significantly different based on age, number of children, work experience, physical activity level, and educational level; however, nurses with permanent employment (P=0.007) and female nurses (P=0.03) had higher cognitive flexibility, and married nurses had lower anxiety (P=0.021).

There is no significant relationship between cognitive flexibility and COVID-19-related anxiety in nurses. The personality traits such as cognitive flexibility is not enough to reduce the high level of anxiety caused the pandemics such as COVID-19 and it requires multiple measures and strategies.

A healthy and vibrant society depends on the presence of citizens with a positive and motivated spirit. Achieving such a society requires that social well-being be realized as a form of mental, individual, and social health in today's communities. Given the novelty of the concept of social well-being, there is yet to be full consensus among researchers on its dimensions and indicators. The widespread interest in social well-being in Iran and globally stems from its conceptual attractiveness as it can delineate prevailing social conditions and serve as a valuable analytical tool for scholars and policymakers in this field. Disorders in social health, such as anxiety, depression, addiction, divorce, and suicide, are crucial issues in contemporary society that warrant extensive study. By investigating their causes and consequences, strategies can be proposed for their prevention and reduction. This study begins with defining the key concepts of social health and the abnormalities resulting from disorders within it. It proceeds to provide statistical insights into these disorders worldwide and in Iran, utilizing keywords such as social health, social disorders, depression, anxiety, addiction, divorce, and suicide, as found in recently published books and articles. The components and indicators of social problems are reviewed, and solutions are proposed for the prevention and mitigation of each social disorder. Research findings indicate that among mortality and disability factors in Iran, depression ranks 4th and anxiety 7th and there is a close relationship between the occurrence of depression, stress, and anxiety in individuals. Globally, 2% of the population suffers from substance use disorders, and the daily smoking rate in Iran is estimated at 10.7%. Moreover, the divorce rate in Iran is reported at 14%, with the highest rates in Alborz, Mazandaran, Semnan, Tehran, and Markazi provinces. Suicide rates in Iran show Ilam, Hamadan, and Kermanshah provinces as having the highest rates. Ilam province is one of the most dangerous regions in Iran, where 28.94 deaths occur due to suicide in every hundred thousand cases. The results indicate significant overlap among these social harms in many aspects, where the occurrence of one can pave the way for another. Thus, preventing social problems such as anxiety and depression can effectively contribute to preventing other social issues such as addiction, divorce, and suicide, thereby enhancing social Health. Therefore, conducting national surveys in this area and making evidence-based decisions can substantially aid in preventing social harm.

Many studies have shown that imagining God is effective in internalizing the emotional control of anxiety. The present study was conducted with the aim of further investigating the effect of this variable.

In this semi-experimental study, 60 patients were selected from the patients who were candidates for heart surgery, admitted to the surgical departments (30 in the experimental group, 30 in the control group). Beck's anxiety questionnaires, God image inventory and researcher-made attributive questionnaire form C (reconstruction of Wiener scale) were used. People in the intervention group, in addition to drug treatment, with cognitive-behavioral method with emphasis on Islamic thoughts, two group discussion sessions; They received problem solving training based on spiritual skills, but the control group only received drug treatment. The data obtained from the pre-test, after the end of the training session and follow-up one month after open heart surgery, were analyzed through SPSS software.

Data analysis showed that the perception of God has a positive correlation with the locus of control (r = 0.723 **), but the locus of control has a negative correlation with the emotion score (r = -0.597). Also, the results showed that the average anxiety scores in the experimental group in the post-test and follow-up phase were significantly different from before the intervention compared to the control group (P=0.0001). Also, the analysis showed that there is a significant difference between the average scores of the control position and the average of the subscales of perception of God (influence, divine providence, acceptance, presence, challenge, benevolence) in the two experimental and control groups in the follow-up phase (P=0.0001).

Designing and implementing group logotherapy can be an effective approach to reduce anxiety before heart surgery and increase the place of internal control and subscales of perception of God.

Diabetes is one of the five common chronic diseases all over the world, which can cause many complications if not treated and controlled. Mental health is an important factor against diseases that can even lead to improvement of physical health in people. The anxiety caused by the coronavirus has led to the fact that the mental health of people with underlying diseases such as diabetes is at risk, and their physical health is also affected by it. Considering the spread of the coronavirus epidemic, the purpose of the present study was to compare the anxiety and depression of patients with diabetes with average individuals during the spread of the coronavirus epidemic.

The present descriptive-analytical and comparative causal study included 300 people (150 diabetic patients, 150 normal people) who were selected by purposive sampling. The data of the present study was collected electronically using a 9-question patient health questionnaire and a 7-question general anxiety questionnaire. The collected data were analyzed using Klomogrov-Smirnov, independent t, t-test and chi-square statistical tests.

In the present study, the average age of the participants was 27.48 years. Moreover, 191 female participants and 109 male participants, and the majority were university educated and married. The special findings of the study indicated that patients with diabetes experienced higher anxiety (t298=3.15, p<0.05) and depression (t298=2.23, p<0.05) than average individuals during the outbreak of corona disease and a statistically significant difference was observed between the two groups in the analysis of these two variables.

The results obtained from the present study indicated that the high level of anxiety and depression during the outbreak of the Corona epidemic made patients with diabetes more vulnerable to psychological problems.

This study aims to investigate the impacts of online prenatal education classes on the Mental health indicators of pregnant women.

This is a randomized quasi-experimental intervention study (one-group pretest-post test). Among the pregnant women referring to the health centers of Esfarayen City, 28 women at 16 to 20 weeks gestation with a low-risk pregnancy were selected by multistage cluster sampling. Six sessions of Skyroom software-based online prenatal classes were conducted for these women in the second trimester. The Depression Anxiety and Stress Scale 21 (DASS-21), a self-report scale, was used to measure anxiety, stress, and depression. Participants complete the questionnaire before the intervention and one month after the last session.

The results showed that the average scores of depression (P < 0.01) and stress (P = 0.02) in pregnant women significantly decreased one month after the Online prenatal education classes. However, no significant change was observed in the average score of anxiety (P > 0.05). There was no significant relationship between demographic and mental health indicators before and after the intervention (P > 0.05).

Online prenatal education classes were successful in lowering pregnant women's levels of stress and depression.  Although more study needs to concentrate on pregnant women’s mental health by providing a more diverse population, the results from this study clearly show the importance of online support for pregnant women.