Tracheal intubation without muscle relaxant with propofol or sevoflurane in children

To compare intubating conditions and cardiovascular changes follow nduction of anesthesia and tracheal intubation in patients receiving either lidocaine-remifentanilpropofol or lidocaine-remifentanil-sevoflurane prior to induction. Methods and materials: In a randomized، double-blind study 75 healthy children patients were assigned to one of two groups: lidocaine 1. 5 mg·kg-1، remifentanil 2 μg·kg-1 and propofol 2 mg·kg-1 (Group P) or lidocaine 1. 5 mg·kg-1، remifentanil 2 μg·kg-1 and sevoflurane (Group S). Then laryngoscopy and tracheal intubation were attempted at BIS 40-50. Intubating conditions were assessed as excellent، good or poor on the basis of ease of ventilation، position of the vocal cords، and patient''s response to intubation and slow inflation of the tracheal cuff. The mean arterial pressure (MAP) and heart rate (HR) were measured before anesthetic agent administration، immediately after tracheal intubation، and five minutes after intubation. Excellent intubating conditions were obtained in 76% of Group P patients and 84% of Group S patients and were not significantly different between the two groups (p<0. 356). Cardiovascular changes following induction of anesthesia and tracheal intubation were not significantly different between the two groups. Lidocaine-remifentanil-sevoflurane is similar and safe like lidocaine-mifentanilpropofolfor tracheal intubation without muscle relaxants in children.