High Serum Levels of TGF-β in Iranians With Chronic HBV Infection
Author(s):
Abstract:
Introduction
The transforming growth factor-β (TGF-β) is an important cytokine with anti-inflammatory properties. The main purpose of this study was to compare the serum levels of TGF-β in a group of chronic HBV infected (CHB) patients as well as healthy individuals from South-East of Iran..Case Presentation
Sixty patients with CHB as well as sixty healthy individuals were enrolled in the study. ELISA technique was applied to measure the serum levels of TGF-β in both groups..Discussion
Our results revealed that the serum levels of TGF-β were significantly increased in CHB patients in compare to healthy controls. According to this result, it may be concluded that high serum levels of TGF-β may be a mechanism by which immune response against HBV is suppressed.Keywords:
Language:
English
Published:
Hepatitis Monthly, Volume:12 Issue: 11, Nov 2012
Page:
11
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