The Effect of Fluorescein Angiography on Full-Field Electroretinography Parameters

To investigate the effect of simultaneously performed fluorescein angiography (FA) on full-field electroretinography (ffERG) parameters. Scotopic and photopic ffERG were performed immediately and 60 minutes after conventional FA in patients with retinal photoreceptor disorders; a-and b-wave amplitudes were compared between recordings obtained at the two time intervals in each patient. Ten eyes of five (3 male and 2 female) patients with mean age of 19.6±3.8 (range, 15-25) years were studied. Intravenous fluorescein administration caused an immediate reduction in ERG waves which was most prominent in rod and maximal combined responses. Mean a-wave amplitude in maximal combined response, rod response and cone response ERGs was 46.0±18.8, 8.0±7.0 and 5.1±2.0? v immediately after FA which was increased to 79.0±30.0, 21.5± 22.5 and 6.5±2.4? v 60 minutes afterwards, respectively (P)