CGD presenting with lymphocytic bronchiolitis in an adult (A report of the first case)

CGD is a rare primary immune deficiency which was first described in children. This disease is mainly seen in children but occasional cases have also been reported in adults. We، hereby، report the first case of CGD associated with lymphocytic bronchiolitis in an adult. The patient is a 40 year old presenting with cough، purulent sputum، dyspnea، and weight loss who received two courses of anti mycobacterial treatment. Based on the findings of chest CT scan، an open lung biopsy was performed and a diagnosis of lymphocytic bronchiolitis was made and appropriate treatment was initiated. It is concluded that in patients with granulomatous lesions who lack strong evidence of tuberculosis، one should not start anti mycobacterial treatment and must always consider CGD in the differential diagnosis.