Diffuse normolipemic plane xanthomas in a healthy male infant

Diffuse normolipemic plane xanthoma is characterized by the presence of yellowish-orange plaques on the eyelids, neck, upper trunk, buttocks and flexural surfaces of the extremities in patients with a normal lipid profile. It mainly affects adults of both sexes. Diffuse normolipemic plane xanthomas are usually associated with reticuloendothelial system disorders, such as multiple myeloma and monoclonal gammopathies. We report a case of diffuse plane xanthomas in an otherwise healthy 1-year-old male infant who developed multiple disseminated non-inflammatory yellowish-orange macules and patches that were not associated with any other symptoms..