Evaluation of Physical Properties of nanocrystal HAp/P3HB composite scaffold for Bone Tissue Engineering

Hydroxyapatite (HAp) has an important role play in the bone tissue engineering because of ability for bone regeneration. In this paper, first, hydroxyapatite nanocrystal powder has been made of bovine bone by thermal analysis at 900°C and then HAp porous with 40, 50 and 60%wt produced by polyurethane sponge replication method. Then scaffolds have been coated by poly-hydroxybutyrate (P3HB) in 30sec and 1min times. In terms of phased studies, morphology and specifying agent groups, it has been used of characterization devices as XRD, SEM, TEM and FT-IR, respectively. Finaly has been presented a scaffold with 90% of porous level in size numbers of 100 and 400mm. As the porosity and morphology of scaffold have indicated, the most excellent scaffold was of 50%wt of HAp which can be utilized in bone tissue engineering.