Evaluation of the Clinical Signs, Paraclinical Findings and Between 2010 and 2011 Referred to Loghman Hakim Hospital Out Comes of Amphetamins Poisning in Children

Amphetamine intoxication is a new life threatening poisoning among children. This study was designed to eval-uate the clinical characteristics، laboratory findings and outcomes of children younger than 13 years due to exposure to derivatives of amphetamines referred to Loghman Hak-im hospital between 2010 and 2011. In this descriptive study، Children (lower than 13 years old) who poisoned with derivatives of amphet-amines and referred to Loghman Hakim hospital between 2010 and 2011 were studi-ed. Vital signs، neurologic، psychologic and gastrointestinal findings، laboratory results، electrocardiographic changes، and also their outcomes before discharge were gathered. Collectively، thirty children were studied. There found 96% agitation، 91%، repetitive movements، 69% insomnia، 60% logorrhea، 94% tachycardia، 84% midriasis، 81% increased deep tendon reflexes، 9% tachypnea، 9% seizures، and 3% hyperthe-rmia. 31 patients (97%) needed intravenous benzodiazepines (diazepam or midazolam). Of them، 12 patients (37. 5%) need to adm-inister one dose of intravenous benzodiaze-pines; 9 cases (28%) required second dose of intravenous benzodiazepines، and 10 cas-es (31. 3%) required repeated doses of int-ravenous benzodiazepines or benzodiaz-epine infusion or intravenous use of halop-eridol. Discussion & Symptoms and signs of poisoning with amphetamines may be mistaken with meningitis and brain hem-orrhage. Hence، knowing the signs and sy-mptoms of this type of poisoning can be treated early to prevent its dangerous side effects.