Frequency of Mitral Regurgitation in Patients with Acute First ST-Elevation Myocardial Infarction and Its Relationship with Location of Myocardial Infarction

Ischemic mitral regurgitation (MR) is frequently seen after the first acute ST-elevation myocardial infarction (MI) and is an independent predictive factor for long-term cardiovascular mortality after MI. Timing and severity of MR after MI is relevant to the location and extent of MI. We sought to evaluate the severity of post-MI ischemic MR and evaluate its relationship with the type of MI. In our case-control study, we enrolled 80 patients with first MI. The patients were divided into two groups: one without MR or with mild ischemic MR (control group) and one with? moderate ischemic MR (case group). Echocardiographic evaluation was done on the third day after MI in both groups, and the severity of ischemic MR was determined based on the American Echocardiographic Association’s guideline. The mean age was significantly higher in the case group (p value < 0.05). The prevalence rates of anterior and inferior-inferolateral MI in the control group were 31 and 66%, respectively. This was seen in 51 and 39% in the case group (p value < 0.05). The main pathology in the case group was mono or bi-leaflet tethering. In addition, ejection fraction was lower in the case group (p value < 0.05). Our findings showed that significant ischemic MR was prevalent in patients with anterior MI