Frequency and Resistance Patterns of Bacterial Isolates from Burn Wounds Infections in Isfahan, Iran

Bacterial infections and antibiotic resistance of their etiologic agents are among the most important challenges facing the burn units. Updated information of bacterial agents causing infection and their resistance patterns has an important role in control and empirical treatment of burn infections. The aim of this study was to determine the frequency and resistance patterns of bacterial isolates from burn wounds infections in hospitalized patients in Emam Mousa Kazem Burn Center in Isfahan، Iran. In a descriptive study of a five-month period، 227 clinical specimens from hospitalized patients in Emam Mousa Kazem Burn Center were examined. Identification of isolates was done using standard method in bacteriology. The susceptibility of the isolates toward antibiotics was tested by agar disk diffusion method. A total of 227 burn wound samples were collected from 131 (57. 7%) men and 96 (42. 3%) women. Pseudomonas aeruginosa (44. 69%) was the most common microorganism causing infection and Acinetobacter spp. (18. 5%) and Staphylococcus aureus (11. 01%) were in next places. According to the results of antimicrobial sensitivity test، 81% of isolates were multidrug resistant (MDR) and high resistance of isolates observed toward co-trimoxazole. This study showed high frequency of infection in burn wounds، specifically، the rising incidence of Acinetobacter infections. Also، high levels of antibiotics resistance of isolates were shown; so، strategies to control the spread of multidrug-resistant strains and review of treatment of burn infection have to be designed and evaluated.