Differential Scanning Calorimetery as a New Tool for Medical Diagnosis

Early detection, cost and time-consuming procedures were always considered in designing new tools for medical diagnosis for various diseases. Detecting biomarkers as important indicators of diseases are promising procedures. Although modern techniques such as proteomics have been solved many problems, they are both cost and time-consuming and also are not much able for detecting protein complexes. Differential scanning calorimetery (DSC) is one of the modern methods with high accuracy and sensitivity, which is capable of diagnosis for diseases at early stages through detecting biomarkers. Plasma & cerebrospinal Fluid (CSF) thermograms of the patients seem to act as specific biological signature that indicate total amount of changes occur in protein structure during the different stages of particular diseases. It is very soon to judge about DSC technique but current studies have revealed new hopes in diagnosis and investigation of the early stages of the diseases. In this article theoretical illustration and medical application of DSC is explained.